Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SSA_RS10980 Genome accession   NC_009009
Coordinates   2241258..2242514 (-) Length   418 a.a.
NCBI ID   WP_033179233.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2243408..2255512 2241258..2242514 flank 894


Gene organization within MGE regions


Location: 2241258..2255512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS10980 (SSA_2246) cinA 2241258..2242514 (-) 1257 WP_033179233.1 competence/damage-inducible protein A Machinery gene
  SSA_RS10985 (SSA_2247) - 2242785..2243195 (+) 411 WP_011837640.1 helix-turn-helix domain-containing protein -
  SSA_RS10990 (SSA_2248) - 2243408..2243899 (-) 492 WP_011837641.1 hypothetical protein -
  SSA_RS10995 (SSA_2249) - 2243896..2244519 (-) 624 WP_011837642.1 ATP-binding cassette domain-containing protein -
  SSA_RS11000 (SSA_2250) - 2244519..2246501 (-) 1983 WP_011837643.1 peptide ABC transporter permease -
  SSA_RS11005 - 2246569..2246907 (-) 339 WP_002894090.1 hypothetical protein -
  SSA_RS11010 (SSA_2251) - 2247209..2248057 (+) 849 WP_011837644.1 helix-turn-helix domain-containing protein -
  SSA_RS11015 - 2248067..2248174 (-) 108 Protein_2141 DNA-3-methyladenine glycosylase I -
  SSA_RS11020 (SSA_2252) - 2248302..2248955 (-) 654 Protein_2142 CPBP family intramembrane glutamic endopeptidase -
  SSA_RS11025 (SSA_2253) - 2248960..2249514 (-) 555 WP_011837646.1 DNA-3-methyladenine glycosylase I -
  SSA_RS11030 (SSA_2254) ruvA 2249524..2250114 (-) 591 WP_011837647.1 Holliday junction branch migration protein RuvA -
  SSA_RS11035 (SSA_2255) - 2250284..2250790 (+) 507 WP_011837648.1 helix-turn-helix domain-containing protein -
  SSA_RS11040 (SSA_2256) - 2250774..2251295 (+) 522 WP_033179235.1 RDD family protein -
  SSA_RS11045 (SSA_2257) mutL 2251331..2253274 (-) 1944 WP_011837650.1 DNA mismatch repair endonuclease MutL -
  SSA_RS11050 (SSA_2258) - 2253479..2254789 (-) 1311 WP_011837651.1 SPFH domain-containing protein -
  SSA_RS11055 (SSA_2259) - 2254817..2255512 (-) 696 WP_011837652.1 zinc ribbon domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44801.86 Da        Isoelectric Point: 4.6948

>NTDB_id=27552 SSA_RS10980 WP_033179233.1 2241258..2242514(-) (cinA) [Streptococcus sanguinis SK36]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSVLEIAQGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELNFDSQAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLLEVDGVSYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIEQQSDPTIAPYAKTGEVTLRLSTKALSQAEADTKFEAVEKEI
LSHKTFEGQSLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DITLRDLEKNGVVSAFTAGKMAEQARKLTQSDLAVSLTGVAGPESLEGHPAGTVFIGLASAAGTETIEVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=27552 SSA_RS10980 WP_033179233.1 2241258..2242514(-) (cinA) [Streptococcus sanguinis SK36]
ATGAAAGCAGAAATTATTGCTGTGGGCACTGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
AAAACTTGCGAGTCTGGGGATTGATGTTTATTTTCAGACAGCAGTAGGGGACAATGAAAATCGTCTCCTATCTGTTTTGG
AAATTGCTCAAGGGCGCAGTAATCTGATTATCCTGACAGGAGGCTTGGGTCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTCTTAGGGCGTGAGCTCAATTTTGACTCACAGGCTGTGGAAAAGTTGGATCGCTTTTTTGCTAGTCGACC
AGATTATGCTCGAACGCCCAATAATGAGCGTCAGGCCCAGCTGGTCGAAGGCTCGACGCCGTTACCAAATGCGACCGGCT
TAGCAGTCGGTGGCTTGCTAGAAGTTGATGGAGTAAGCTATGTAGTCTTGCCTGGCCCGCCTAGTGAGCTCAAGCCCATG
GTCAATAACGAGCTGGTTCCCCTCTTATCCACAGGCCAGAAATTGTATTCACGGGTGCTGCGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGAGCAGCAGAGTGACCCCACCATTGCTCCTTATGCAAAGACAGGAG
AAGTTACCCTACGACTGTCTACCAAGGCTCTGAGTCAGGCAGAAGCCGACACTAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGTCCCATAAGACTTTTGAGGGACAGTCACTGTCAGAGATTTTCTATGGTTACGGGGATGACAATTCCTTGGCACAGGT
GGCTTTTGACTTGCTGAAGAGTCAAGGAAAGACGATTTCGGCGGCGGAGAGTCTGACAGCAGGGCTCTTTCAGGCGACCT
TGGCTGATTTTGCTGGAGCCTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAAGAAAAGAGCCGGATGCTG
GATATTACGTTGAGAGACCTGGAGAAGAACGGAGTCGTTTCAGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACTCAGAGTGACTTGGCTGTCAGTCTGACAGGTGTGGCAGGCCCAGAGTCACTGGAAGGTCATCCAGCAGGGACCG
TTTTTATCGGCTTAGCAAGTGCTGCTGGAACAGAAACTATTGAGGTCAATATTGCTGGACGAAGTCGGCGTGATGTGCGG
AAAATTGCTGTTCTGCACGCCTTCAACCTAGTACGAAAAACTTTATTAAATAGCTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.938

99.761

0.778
  cinA Streptococcus mitis NCTC 12261

77.458

99.761

0.773
  cinA Streptococcus pneumoniae TIGR4

76.499

99.761

0.763
  cinA Streptococcus pneumoniae Rx1

76.499

99.761

0.763
  cinA Streptococcus pneumoniae R6

76.499

99.761

0.763
  cinA Streptococcus pneumoniae D39

76.259

99.761

0.761
  cinA Streptococcus mutans UA159

74.163

100

0.742
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

100

0.469

Multiple sequence alignment