Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   C4N11_RS10150 Genome accession   NZ_CP026670
Coordinates   1902268..1903524 (-) Length   418 a.a.
NCBI ID   WP_000642705.1    Uniprot ID   A0A0T7I3F9
Organism   Streptococcus pneumoniae strain endophthalmitis isolate 335     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1897268..1908524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4N11_RS10120 (C4N11_10120) - 1897325..1897531 (-) 207 WP_000366093.1 hypothetical protein -
  C4N11_RS10125 (C4N11_10125) - 1897518..1897679 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  C4N11_RS10130 (C4N11_10130) lytA 1898038..1898994 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  C4N11_RS10135 (C4N11_10135) - 1899370..1900740 (-) 1371 WP_001036278.1 MATE family efflux transporter -
  C4N11_RS10145 (C4N11_10145) recA 1901047..1902213 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  C4N11_RS10150 (C4N11_10150) cinA 1902268..1903524 (-) 1257 WP_000642705.1 competence/damage-inducible protein A Machinery gene
  C4N11_RS10155 (C4N11_10155) - 1903609..1904625 (-) 1017 WP_000239284.1 LCP family protein -
  C4N11_RS10160 (C4N11_10160) - 1904633..1905151 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  C4N11_RS10165 (C4N11_10165) tsaE 1905141..1905584 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  C4N11_RS10170 (C4N11_10170) comM 1905670..1906290 (-) 621 WP_000839908.1 hypothetical protein Regulator
  C4N11_RS10180 (C4N11_10180) - 1906673..1907536 (-) 864 WP_001093641.1 helix-turn-helix domain-containing protein -
  C4N11_RS12695 (C4N11_10185) - 1907728..1907898 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  C4N11_RS10190 (C4N11_10190) pneA1 1908001..1908225 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  C4N11_RS10195 (C4N11_10195) pneA2 1908232..1908420 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45047.43 Da        Isoelectric Point: 4.6064

>NTDB_id=271455 C4N11_RS10150 WP_000642705.1 1902268..1903524(-) (cinA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=271455 C4N11_RS10150 WP_000642705.1 1902268..1903524(-) (cinA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTAACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T7I3F9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus pneumoniae Rx1

99.043

100

0.99
  cinA Streptococcus pneumoniae R6

99.043

100

0.99
  cinA Streptococcus pneumoniae D39

98.804

100

0.988
  cinA Streptococcus mitis SK321

94.258

100

0.943
  cinA Streptococcus mitis NCTC 12261

94.019

100

0.94
  cinA Streptococcus mutans UA159

71.292

100

0.713
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment