Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CU052_RS05915 Genome accession   NZ_CP025537
Coordinates   1255848..1256957 (+) Length   369 a.a.
NCBI ID   WP_005450977.1    Uniprot ID   A0A8B3DBR0
Organism   Vibrio harveyi strain 345     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1250848..1261957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU052_RS05895 (CU052_06300) rsmB 1251767..1253050 (-) 1284 WP_005450981.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CU052_RS05900 (CU052_06305) fmt 1253132..1254079 (-) 948 WP_009701851.1 methionyl-tRNA formyltransferase -
  CU052_RS05905 (CU052_06310) def 1254113..1254631 (-) 519 WP_005450979.1 peptide deformylase -
  CU052_RS05910 (CU052_06315) - 1254770..1255864 (+) 1095 WP_101904381.1 LysM peptidoglycan-binding domain-containing protein -
  CU052_RS05915 (CU052_06320) dprA 1255848..1256957 (+) 1110 WP_005450977.1 DNA-processing protein DprA Machinery gene
  CU052_RS05920 (CU052_06325) - 1256960..1257439 (+) 480 WP_005429833.1 DUF494 family protein -
  CU052_RS05925 (CU052_06330) - 1257463..1258032 (+) 570 WP_005450974.1 type I DNA topoisomerase -
  CU052_RS05930 (CU052_06335) - 1258096..1259229 (-) 1134 WP_005450972.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  CU052_RS05935 (CU052_06340) purE 1259234..1259719 (-) 486 WP_005440742.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  CU052_RS05940 (CU052_06345) - 1259919..1260476 (+) 558 WP_101904382.1 L-threonylcarbamoyladenylate synthase -
  CU052_RS05945 (CU052_06350) hemF 1260511..1261428 (+) 918 WP_005450967.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 369 a.a.        Molecular weight: 39779.49 Da        Isoelectric Point: 6.0412

>NTDB_id=262390 CU052_RS05915 WP_005450977.1 1255848..1256957(+) (dprA) [Vibrio harveyi strain 345]
MKLRNDTDLAAWLKLSCLPGIGGVKMNKLLSKDTPSNIVGYSTEQLQLLGFTTKQLQAWSEVDKEVDACLTWVSASSHHH
IVTLADTLYPPLLKQTVAPPPLLFIKGEASCLSQPQIAMVGSRNASVDGLQHARQFAADLVKHDLIVTSGLALGIDGHAH
DGALQADGKTIAVLGSGLEQVYPARHRGLARRVMENGALVSEFRPDAKPRAENFPRRNRIISGLSLGVLVVEAAEKSGSL
ITARYALEQDREVFAIPASINAPNASGGNQLIRNGACLVQNTQEVLNEIQSLLDWSINQSLDLFSTPIDEEELPFPQLLA
NVGNEATPVDILASRTNIPVQEVMMQLLELELSGHVVAVSGGYIRKGRG

Nucleotide


Download         Length: 1110 bp        

>NTDB_id=262390 CU052_RS05915 WP_005450977.1 1255848..1256957(+) (dprA) [Vibrio harveyi strain 345]
ATGAAACTACGCAATGATACTGACCTCGCCGCCTGGTTAAAGCTGAGCTGCTTGCCAGGCATTGGCGGGGTGAAGATGAA
TAAGCTGCTGAGTAAAGATACGCCAAGCAATATTGTCGGATACTCAACTGAGCAGCTTCAGCTTTTGGGTTTTACCACGA
AGCAACTGCAAGCATGGTCTGAGGTCGATAAAGAAGTCGACGCTTGTCTTACTTGGGTTAGCGCCTCATCTCATCATCAT
ATTGTTACTTTGGCGGATACTCTGTATCCCCCACTTCTCAAACAAACGGTCGCTCCACCTCCTTTACTATTTATAAAGGG
AGAAGCGAGTTGTTTGTCTCAACCTCAAATTGCCATGGTCGGCAGCCGTAATGCTAGTGTTGATGGGCTTCAACACGCAC
GTCAGTTCGCTGCAGATTTGGTGAAACATGATCTGATTGTTACCAGTGGTTTGGCTTTGGGTATCGATGGACACGCTCAT
GATGGTGCTTTGCAAGCGGACGGTAAAACCATTGCGGTATTGGGTTCAGGGTTAGAGCAAGTTTATCCAGCCCGTCACCG
AGGTTTAGCGCGGCGAGTGATGGAAAACGGTGCGTTAGTCTCTGAGTTTCGCCCAGATGCGAAACCTCGAGCAGAAAACT
TCCCACGACGTAATCGAATCATTAGTGGTTTGTCGCTTGGCGTGTTGGTTGTCGAAGCAGCAGAAAAGAGTGGCTCATTA
ATCACCGCTCGCTACGCTCTTGAGCAAGACCGTGAAGTTTTCGCTATACCAGCTTCGATTAATGCTCCCAATGCCAGTGG
TGGTAATCAGTTGATTCGTAATGGGGCTTGTCTCGTACAAAACACTCAAGAGGTGTTGAATGAAATACAGTCTTTGCTCG
ACTGGTCTATTAATCAGAGCTTGGATTTATTTTCTACGCCAATTGATGAAGAAGAATTGCCATTTCCTCAGCTGTTAGCT
AACGTAGGAAATGAGGCTACACCAGTTGATATTCTTGCAAGCAGGACCAATATACCTGTCCAAGAAGTCATGATGCAGCT
CTTAGAGCTTGAGCTTTCAGGGCATGTTGTTGCAGTATCCGGTGGCTATATTCGAAAGGGGAGGGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(78-280)

DprA winged helix domain (DprA_WH)

(314-362)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A8B3DBR0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

93.225

100

0.932
  dprA Vibrio cholerae strain A1552

58.649

100

0.588
  dprA Glaesserella parasuis strain SC1401

46.667

100

0.474
  dprA Haemophilus influenzae Rd KW20

44.706

92.141

0.412
  dprA Legionella pneumophila strain ERS1305867

49.324

80.217

0.396
  dprA Neisseria meningitidis strain C311

36.829

100

0.39
  dprA Neisseria meningitidis MC58

36.829

100

0.39
  dprA Neisseria gonorrhoeae MS11

35.659

100

0.374
  dprA Neisseria gonorrhoeae strain FA1090

35.401

100

0.371

Multiple sequence alignment