Detailed information NTG0258034

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: DK235_RS00770
• Genome accession: NZ_CP030017
• Coordinates: 121993..122400 (+)
• Length: 135 a.a.
• NCBI ID: WP_011921721.1
• Uniprot ID: A0A0H3MT39
• Organism: Streptococcus suis strain ISU1606
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 116993..127400

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK235_RS00745 (DK235_00795)	-	118401..118766 (+)	366	WP_002936568.1	DUF1033 family protein	-
DK235_RS00750 (DK235_00800)	-	118801..119744 (-)	944	Protein_115	S66 peptidase family protein	-
DK235_RS00755 (DK235_00805)	comGA	119830..120780 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
DK235_RS00760 (DK235_00810)	comGB	120692..121729 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK235_RS00765 (DK235_00815)	comGC	121731..122012 (+)	282	WP_053865943.1	competence type IV pilus major pilin ComGC	Machinery gene
DK235_RS00770 (DK235_00820)	comGD	121993..122400 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	Machinery gene
DK235_RS00775 (DK235_00825)	comGE	122372..122665 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK235_RS00780 (DK235_00830)	comGF/cglF	122652..123086 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK235_RS00785 (DK235_00835)	comGG	123064..123474 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	Machinery gene
DK235_RS00790 (DK235_00840)	comGH	123531..124484 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
DK235_RS00795 (DK235_00845)	-	124534..125721 (+)	1188	WP_012775422.1	acetate kinase	-
DK235_RS00800 (DK235_00850)	-	126036..126587 (+)	552	WP_012774908.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 135 a.a.
• Molecular weight: 15367.59 Da
• Isoelectric Point: 8.3926

>NTDB_id=258034 DK235_RS00770 WP_011921721.1 121993..122400(+) (comGD) [Streptococcus suis strain ISU1606]
MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIFLWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQ
AVEVPRNVEVLEEKTIQFEEDGGNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE

Nucleotide

• Length: 408 bp

>NTDB_id=258034 DK235_RS00770 WP_011921721.1 121993..122400(+) (comGD) [Streptococcus suis strain ISU1606]
ATGCTACGGCGAAAAAATAAGGCTTTTACCCTGTTTGAAAGCCTGCTGACCTTGTTGGTTGTCAGTTTTTTAGCTGTTTC
CTTATCAGGAACAGTACAAACGGTCTTTCGGTCTGTTCAGGAAGAAATTTTTCTCTGGGAATTTGAGGCCATCTATAAAG
ACAGTCAGAAATTAGCAGCCAGTTCCCACAAAAAAGTGAACCTTGCTATCGGTGGACAGGAGGTTACAAATGGTTATCAG
GCTGTAGAGGTGCCCAGAAACGTAGAGGTCTTAGAGGAGAAAACTATTCAGTTTGAAGAAGATGGTGGAAATTCTTCTCT
GACCAAGATTCGTTTTCACCTTAGTCAAAAAATAGTCACGTATCAATTATATATAGGGAGTGGTCGCTATAAGAAAACAG
AAGAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0H3MT39

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus gordonii str. Challis substr. CH1	48.031	94.074	0.452
comGD	Streptococcus mutans UA140	46.512	95.556	0.444
comGD	Streptococcus mutans UA159	46.512	95.556	0.444
comGD/cglD	Streptococcus pneumoniae TIGR4	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae R6	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae Rx1	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae D39	44.961	95.556	0.43
comGD/cglD	Streptococcus mitis NCTC 12261	44.186	95.556	0.422
comGD/cglD	Streptococcus mitis SK321	43.411	95.556	0.415
comGD	Lactococcus lactis subsp. cremoris KW2	39.062	94.815	0.37