Detailed information NTG0258036

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CWI35_RS12195
• Genome accession: NZ_CP025074
• Coordinates: 2364248..2365429 (+)
• Length: 393 a.a.
• NCBI ID: WP_023633632.1
• Uniprot ID: A0A7U9JCE3
• Organism: [Bacillus] caldolyticus strain NEB414
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2359248..2370429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWI35_RS12180 (CWI35_12150)	-	2359658..2362105 (-)	2448	WP_119877809.1	SH3 domain-containing protein	-
CWI35_RS12185 (CWI35_12155)	-	2362347..2363354 (-)	1008	WP_023633631.1	LCP family protein	-
CWI35_RS12190 (CWI35_12160)	-	2363387..2364028 (-)	642	WP_014196788.1	YigZ family protein	-
CWI35_RS12195 (CWI35_12165)	degS	2364248..2365429 (+)	1182	WP_023633632.1	sensor histidine kinase	Regulator
CWI35_RS12200 (CWI35_12170)	degU	2365426..2366100 (+)	675	WP_020278885.1	response regulator transcription factor	Regulator
CWI35_RS12205 (CWI35_12175)	-	2366356..2367201 (+)	846	WP_011232619.1	DegV family protein	-
CWI35_RS12215 (CWI35_12185)	-	2368061..2369452 (+)	1392	WP_119877810.1	DEAD/DEAH box helicase	-
CWI35_RS12220 (CWI35_12190)	-	2369449..2370141 (+)	693	WP_014196780.1	ComF family protein	-

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 45666.30 Da
• Isoelectric Point: 7.2271

>NTDB_id=258036 CWI35_RS12195 WP_023633632.1 2364248..2365429(+) (degS) [[Bacillus] caldolyticus strain NEB414]
MAEAKQWDVKQLDRIVEKMIDTVQHSKDEIFRIGEQSRQEHDHLLRELEEVKQLTVQAIEEADQLEMKARQARRRLSEVS
QNFSTHSEQDIREAYEAAHELHMKLTMVREREKQLRLRRDELERRLASLAQIIERADYLVGQITVVLHYLNSDFRQVGEL
IEGAKQKQEFGLKIIEAQEEERRRLSREIHDGPAQLLAHVLLRSDLVEKVIKERGTEAAIAEIRDFRKMVRSALSEVRRI
IYDLRPMALDDLGLVPTLKKYLQTTEEYNKGVHISFVHIGEEIRLPSRMEAAVFRLVQESVQNALKHAEARHIDVKMEVT
CHHLLVSVKDDGKGFDPSVKKENAFGLIGMRERVELLGGTLDIRSKIGSGTTVFIRVPLDRSTDKTNKEERKR

Nucleotide

• Length: 1182 bp

>NTDB_id=258036 CWI35_RS12195 WP_023633632.1 2364248..2365429(+) (degS) [[Bacillus] caldolyticus strain NEB414]
ATGGCTGAGGCAAAACAGTGGGACGTGAAGCAATTAGATCGGATTGTCGAAAAAATGATCGACACCGTTCAACACAGCAA
AGACGAAATTTTCCGCATCGGGGAGCAGTCGCGTCAAGAGCACGACCATTTGCTTCGCGAACTCGAGGAGGTGAAGCAGC
TGACCGTGCAGGCGATCGAAGAAGCGGATCAGCTGGAAATGAAGGCGCGTCAGGCGCGCCGCCGCCTGTCGGAAGTGAGT
CAAAACTTTTCCACCCACTCGGAGCAAGATATTCGCGAGGCGTATGAAGCGGCGCATGAGTTGCATATGAAGCTGACGAT
GGTGCGCGAGCGGGAGAAACAGCTGCGGCTGCGCCGCGACGAGCTCGAGCGGAGATTGGCGAGCCTTGCGCAAATTATCG
AACGCGCCGATTATTTAGTTGGACAAATTACGGTCGTGCTCCACTACTTAAACAGCGATTTCCGCCAGGTCGGCGAGCTT
ATTGAAGGAGCGAAGCAAAAGCAGGAATTTGGGCTGAAAATCATCGAAGCCCAGGAAGAAGAGCGGCGGCGGCTGTCGCG
GGAAATCCATGACGGCCCGGCGCAGCTGCTCGCTCACGTCCTTCTTCGGTCTGATTTGGTCGAAAAGGTGATCAAAGAGC
GAGGGACAGAGGCGGCGATCGCCGAGATTCGTGATTTTCGCAAAATGGTGCGTTCGGCTTTGTCCGAAGTGCGCCGCATC
ATTTACGATTTGCGGCCGATGGCGCTTGATGATTTAGGATTGGTTCCGACGCTAAAAAAATACTTGCAAACGACCGAAGA
ATATAACAAGGGAGTCCACATTTCCTTTGTACATATCGGCGAAGAAATTCGGCTGCCGTCGCGGATGGAGGCGGCCGTGT
TTCGGCTTGTCCAAGAATCGGTGCAAAACGCCTTGAAGCATGCCGAAGCGCGCCATATCGACGTCAAAATGGAAGTGACG
TGCCACCATCTGCTTGTCAGTGTCAAAGACGATGGCAAAGGATTTGATCCATCGGTCAAAAAAGAAAATGCGTTCGGCTT
GATTGGAATGCGGGAGCGGGTGGAGCTGCTCGGCGGCACGCTCGACATCCGCTCAAAGATTGGCAGCGGAACGACCGTGT
TCATTCGCGTTCCGCTCGACCGTTCGACTGACAAAACGAACAAGGAGGAAAGGAAACGATGA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (292-380)

• Histidine kinase (HisKA_3) (181-249)

• Sensor protein DegS (DegS) (13-171)

3D structure

• AlphaFold DB: A0A7U9JCE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	58.839	96.438	0.567