Detailed information    

insolico Bioinformatically predicted

Overview

Name   degU   Type   Regulator
Locus tag   CWI35_RS12200 Genome accession   NZ_CP025074
Coordinates   2365426..2366100 (+) Length   224 a.a.
NCBI ID   WP_020278885.1    Uniprot ID   U2X4C2
Organism   [Bacillus] caldolyticus strain NEB414     
Function   activation of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2360426..2371100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI35_RS12185 (CWI35_12155) - 2362347..2363354 (-) 1008 WP_023633631.1 LCP family protein -
  CWI35_RS12190 (CWI35_12160) - 2363387..2364028 (-) 642 WP_014196788.1 YigZ family protein -
  CWI35_RS12195 (CWI35_12165) degS 2364248..2365429 (+) 1182 WP_023633632.1 sensor histidine kinase Regulator
  CWI35_RS12200 (CWI35_12170) degU 2365426..2366100 (+) 675 WP_020278885.1 response regulator transcription factor Regulator
  CWI35_RS12205 (CWI35_12175) - 2366356..2367201 (+) 846 WP_011232619.1 DegV family protein -
  CWI35_RS12215 (CWI35_12185) - 2368061..2369452 (+) 1392 WP_119877810.1 DEAD/DEAH box helicase -
  CWI35_RS12220 (CWI35_12190) - 2369449..2370141 (+) 693 WP_014196780.1 ComF family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25206.92 Da        Isoelectric Point: 5.6709

>NTDB_id=258037 CWI35_RS12200 WP_020278885.1 2365426..2366100(+) (degU) [[Bacillus] caldolyticus strain NEB414]
MKTRIAIIDDHQLFREGIKRILEFEGDFEVVAEGSDGSEALSIVETYRPDLVLMDINMPDINGVEATKQLIEAYPDTKVV
VLSIHDDENYVMRALQTGATGYLLKEMDADTLIEAVRIVAEGGSYLHPKVTHNLIREYRRLTTEKGGAVVKQEVRRPLHL
LTRRECEVLQLLADGKSNRAIGEALYISEKTVKNHVSSILQKLNVNDRTQAVVVAIKNGWVEVR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=258037 CWI35_RS12200 WP_020278885.1 2365426..2366100(+) (degU) [[Bacillus] caldolyticus strain NEB414]
ATGAAAACACGCATCGCGATTATCGACGATCACCAGCTGTTTCGCGAGGGCATCAAGCGCATTTTGGAATTTGAGGGCGA
TTTTGAAGTCGTGGCGGAAGGAAGCGACGGAAGCGAAGCGCTTTCAATCGTCGAAACATACCGACCCGATTTGGTGCTGA
TGGACATTAACATGCCGGACATCAACGGCGTTGAGGCGACGAAACAGCTGATTGAAGCTTACCCTGATACGAAAGTCGTC
GTGCTGTCGATTCATGACGATGAAAACTATGTCATGCGCGCCTTGCAGACGGGAGCGACCGGGTATTTGTTGAAGGAGAT
GGACGCCGATACACTCATTGAGGCGGTGAGAATCGTCGCGGAAGGCGGTTCGTACTTGCATCCGAAAGTGACGCACAACT
TGATTCGCGAATACCGCCGATTGACGACGGAAAAAGGCGGCGCAGTGGTTAAGCAGGAGGTGCGCCGCCCGCTTCATTTG
CTGACGCGGCGCGAGTGCGAAGTGCTGCAGCTGTTGGCTGACGGCAAAAGCAACCGCGCCATCGGCGAGGCGCTTTACAT
TAGCGAAAAAACGGTGAAAAACCATGTCAGCAGCATCCTGCAAAAGTTAAACGTCAACGACCGGACGCAAGCCGTTGTGG
TTGCGATCAAAAACGGCTGGGTGGAAGTGCGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(160-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2X4C2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degU Bacillus subtilis subsp. subtilis str. 168

76.652

100

0.777
  vraR Staphylococcus aureus N315

39.462

99.554

0.393

Multiple sequence alignment