Detailed information
Bioinformatically predicted
Overview
| Name | pilC | Type | Machinery gene |
| Locus tag | CRN80_RS03705 | Genome accession | NZ_CP023969 |
| Coordinates | 774810..776018 (+) | Length | 402 a.a. |
| NCBI ID | WP_098949596.1 | Uniprot ID | A0A921NKX7 |
| Organism | Pseudomonas sp. FDAARGOS_380 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 718776..801573 | 774810..776018 | within | 0 |
Gene organization within MGE regions
Location: 718776..801573
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CRN80_RS03500 (CRN80_03500) | - | 718776..720500 (-) | 1725 | WP_098949576.1 | ABC transporter ATP-binding protein/permease | - |
| CRN80_RS03505 (CRN80_03505) | - | 720601..721161 (-) | 561 | WP_003171731.1 | response regulator transcription factor | - |
| CRN80_RS03510 (CRN80_03510) | - | 721154..722416 (-) | 1263 | WP_003188495.1 | ATP-binding protein | - |
| CRN80_RS03515 (CRN80_03515) | - | 722622..723335 (+) | 714 | WP_032893587.1 | SIMPL domain-containing protein | - |
| CRN80_RS03520 (CRN80_03520) | - | 723518..726874 (+) | 3357 | WP_098949577.1 | dermonecrotic toxin domain-containing protein | - |
| CRN80_RS03525 (CRN80_03525) | - | 726955..728556 (+) | 1602 | WP_032893590.1 | ABC transporter substrate-binding protein | - |
| CRN80_RS03530 (CRN80_03530) | - | 728815..730443 (+) | 1629 | WP_003188490.1 | ABC transporter substrate-binding protein | - |
| CRN80_RS03535 (CRN80_03535) | - | 730810..732354 (+) | 1545 | WP_370874668.1 | ABC transporter substrate-binding protein | - |
| CRN80_RS03540 (CRN80_03540) | - | 732525..733919 (+) | 1395 | WP_003188488.1 | OprD family outer membrane porin | - |
| CRN80_RS03545 (CRN80_03545) | - | 734000..735598 (+) | 1599 | WP_032893592.1 | ABC transporter substrate-binding protein | - |
| CRN80_RS03550 (CRN80_03550) | - | 735675..736685 (+) | 1011 | WP_003171721.1 | ABC transporter permease subunit | - |
| CRN80_RS03555 (CRN80_03555) | - | 736696..737607 (+) | 912 | WP_003188486.1 | ABC transporter permease subunit | - |
| CRN80_RS03560 (CRN80_03560) | - | 737618..738586 (+) | 969 | WP_034126279.1 | ABC transporter ATP-binding protein | - |
| CRN80_RS03565 (CRN80_03565) | - | 738586..739557 (+) | 972 | WP_003188483.1 | peptide ABC transporter ATP-binding protein | - |
| CRN80_RS03570 (CRN80_03570) | - | 739982..742240 (+) | 2259 | WP_098949578.1 | TonB-dependent siderophore receptor | - |
| CRN80_RS03575 (CRN80_03575) | - | 742324..742578 (-) | 255 | WP_098949579.1 | hypothetical protein | - |
| CRN80_RS03580 (CRN80_03580) | - | 742852..744435 (-) | 1584 | WP_003188476.1 | peptide chain release factor 3 | - |
| CRN80_RS03585 (CRN80_03585) | - | 744768..745484 (+) | 717 | WP_098949580.1 | ABC transporter permease | - |
| CRN80_RS03590 (CRN80_03590) | - | 745504..746397 (+) | 894 | WP_032893595.1 | glycine betaine ABC transporter substrate-binding protein | - |
| CRN80_RS03595 (CRN80_03595) | - | 746410..747063 (+) | 654 | WP_003188473.1 | ABC transporter permease | - |
| CRN80_RS03600 (CRN80_03600) | - | 747060..748217 (+) | 1158 | WP_003188471.1 | betaine/proline/choline family ABC transporter ATP-binding protein | - |
| CRN80_RS03605 (CRN80_03605) | - | 748677..749840 (+) | 1164 | WP_032893596.1 | type III PLP-dependent enzyme | - |
| CRN80_RS03610 (CRN80_03610) | - | 749962..750705 (-) | 744 | WP_098949581.1 | tetratricopeptide repeat protein | - |
| CRN80_RS03615 (CRN80_03615) | - | 750708..751388 (-) | 681 | WP_003188464.1 | Fe2+-dependent dioxygenase | - |
| CRN80_RS03620 (CRN80_03620) | - | 751594..753909 (+) | 2316 | WP_098949582.1 | TonB-dependent siderophore receptor | - |
| CRN80_RS03625 (CRN80_03625) | - | 754033..756558 (+) | 2526 | WP_098949583.1 | sulfite reductase flavoprotein subunit alpha | - |
| CRN80_RS03630 (CRN80_03630) | - | 756696..758237 (-) | 1542 | WP_098949584.1 | alkaline phosphatase | - |
| CRN80_RS03635 (CRN80_03635) | - | 758444..760153 (-) | 1710 | WP_032893606.1 | PTS fructose-like transporter subunit IIB | - |
| CRN80_RS03640 (CRN80_03640) | pfkB | 760165..761085 (-) | 921 | WP_098949585.1 | 1-phosphofructokinase | - |
| CRN80_RS03645 (CRN80_03645) | ptsP | 761086..763944 (-) | 2859 | WP_098949586.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| CRN80_RS03650 (CRN80_03650) | cra | 764229..765224 (+) | 996 | WP_098949587.1 | catabolite repressor/activator | - |
| CRN80_RS03655 (CRN80_03655) | - | 765227..766003 (+) | 777 | WP_098949588.1 | TatD family hydrolase | - |
| CRN80_RS03660 (CRN80_03660) | - | 765950..766378 (-) | 429 | WP_098949589.1 | hypothetical protein | - |
| CRN80_RS32035 | - | 766504..767433 (-) | 930 | WP_371861808.1 | methyl-accepting chemotaxis protein | - |
| CRN80_RS32040 | - | 767410..768501 (-) | 1092 | Protein_701 | methyl-accepting chemotaxis protein | - |
| CRN80_RS03670 (CRN80_03670) | ampE | 768779..769615 (-) | 837 | WP_098949591.1 | regulatory signaling modulator protein AmpE | - |
| CRN80_RS03675 (CRN80_03675) | ampD | 769612..770175 (-) | 564 | WP_098949592.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| CRN80_RS03680 (CRN80_03680) | - | 770237..772384 (-) | 2148 | WP_098949593.1 | DUF1631 domain-containing protein | - |
| CRN80_RS03685 (CRN80_03685) | nadC | 772632..773480 (+) | 849 | WP_098949594.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| CRN80_RS03690 (CRN80_03690) | - | 773600..773905 (-) | 306 | WP_032893620.1 | DUF6388 family protein | - |
| CRN80_RS03700 (CRN80_03700) | - | 774195..774608 (-) | 414 | WP_098949595.1 | pilin | - |
| CRN80_RS03705 (CRN80_03705) | pilC | 774810..776018 (+) | 1209 | WP_098949596.1 | type II secretion system F family protein | Machinery gene |
| CRN80_RS03710 (CRN80_03710) | pilD | 776015..776881 (+) | 867 | WP_098949597.1 | A24 family peptidase | Machinery gene |
| CRN80_RS03715 (CRN80_03715) | coaE | 776878..777501 (+) | 624 | WP_032893625.1 | dephospho-CoA kinase | - |
| CRN80_RS03720 (CRN80_03720) | yacG | 777498..777698 (+) | 201 | WP_003188437.1 | DNA gyrase inhibitor YacG | - |
| CRN80_RS03725 (CRN80_03725) | - | 777695..777910 (-) | 216 | WP_003171680.1 | hypothetical protein | - |
| CRN80_RS03730 (CRN80_03730) | - | 777975..778664 (-) | 690 | WP_098949598.1 | energy-coupling factor ABC transporter permease | - |
| CRN80_RS03735 (CRN80_03735) | - | 778793..779422 (+) | 630 | WP_098949599.1 | DUF1780 domain-containing protein | - |
| CRN80_RS03740 (CRN80_03740) | - | 779477..779650 (+) | 174 | WP_032893628.1 | DUF3094 family protein | - |
| CRN80_RS03745 (CRN80_03745) | - | 779711..781009 (+) | 1299 | WP_014716868.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| CRN80_RS03755 (CRN80_03755) | - | 781525..782385 (+) | 861 | WP_008437313.1 | ParA family protein | - |
| CRN80_RS03760 (CRN80_03760) | - | 782387..783145 (+) | 759 | WP_008437314.1 | hypothetical protein | - |
| CRN80_RS03765 (CRN80_03765) | - | 783142..783843 (+) | 702 | WP_008437315.1 | DUF2786 domain-containing protein | - |
| CRN80_RS03770 (CRN80_03770) | - | 783840..784559 (+) | 720 | WP_020301295.1 | HNH endonuclease signature motif containing protein | - |
| CRN80_RS03775 (CRN80_03775) | - | 784543..784761 (+) | 219 | WP_008437317.1 | hypothetical protein | - |
| CRN80_RS03780 (CRN80_03780) | dnaB | 784758..786107 (+) | 1350 | WP_008437319.1 | replicative DNA helicase | - |
| CRN80_RS03790 (CRN80_03790) | - | 786288..786809 (+) | 522 | WP_008437321.1 | hypothetical protein | - |
| CRN80_RS31460 (CRN80_03795) | - | 786806..787045 (+) | 240 | WP_008437325.1 | type II toxin-antitoxin system HicA family toxin | - |
| CRN80_RS03800 (CRN80_03800) | yejK | 787045..788046 (+) | 1002 | WP_008437326.1 | nucleoid-associated protein YejK | - |
| CRN80_RS31970 (CRN80_03805) | - | 788080..788316 (+) | 237 | WP_008437327.1 | Arc family DNA-binding protein | - |
| CRN80_RS03810 (CRN80_03810) | - | 788313..790079 (+) | 1767 | WP_008437328.1 | ParB family protein | - |
| CRN80_RS03815 (CRN80_03815) | - | 790108..790803 (+) | 696 | WP_008437329.1 | DUF2857 domain-containing protein | - |
| CRN80_RS03820 (CRN80_03820) | - | 790800..792101 (+) | 1302 | WP_019816979.1 | STY4528 family pathogenicity island replication protein | - |
| CRN80_RS30400 | - | 792155..792895 (+) | 741 | WP_138183495.1 | hypothetical protein | - |
| CRN80_RS03825 (CRN80_03825) | - | 792964..793689 (+) | 726 | WP_008437331.1 | PFL_4669 family integrating conjugative element protein | - |
| CRN80_RS03830 (CRN80_03830) | - | 793695..794234 (+) | 540 | WP_008437334.1 | DUF3158 family protein | - |
| CRN80_RS03835 (CRN80_03835) | - | 794250..794714 (+) | 465 | WP_008437336.1 | single-stranded DNA-binding protein | - |
| CRN80_RS03840 (CRN80_03840) | - | 794825..795250 (+) | 426 | WP_008437339.1 | hypothetical protein | - |
| CRN80_RS03845 (CRN80_03845) | - | 795429..795626 (+) | 198 | WP_073845721.1 | CrpP family ICE-associated protein | - |
| CRN80_RS03850 (CRN80_03850) | topA | 795726..797630 (+) | 1905 | WP_008437341.1 | type I DNA topoisomerase | - |
| CRN80_RS03855 (CRN80_03855) | - | 797741..799621 (+) | 1881 | WP_019818088.1 | hypothetical protein | - |
| CRN80_RS03860 (CRN80_03860) | - | 799618..801573 (+) | 1956 | WP_024073377.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 402 a.a. Molecular weight: 43512.11 Da Isoelectric Point: 10.2936
>NTDB_id=251002 CRN80_RS03705 WP_098949596.1 774810..776018(+) (pilC) [Pseudomonas sp. FDAARGOS_380]
MNDTPTIYAWEGINRKGRRVSGQIAGHNLALIKVQLRQQGICPERVRKKSCALPTFKTRITPVDIALFTRQLATLLKAGI
PLLQAFDIISEGVENPQLRELVKALKQHIASGHPLAAALRQYPRHFDELYCNLVAAGEMAGALETLLERVAIHLEKSQRL
KTRIKKAMTYPIAVLVIATGVSTVLLIHVVPQFQNLFAGVNGQLPGFTLGVIALSELLQQAWWMLGLGVGAALVAGRHAY
RTHPGFRHGWAAGLLKVPVAGKLLHKSAVARYARTLSTTFAAGVPLVQALGSVAGAVGHGPFKQAIERMRHDVSTGMQLN
QSMHNSGLFPGMAIQMTAIGEESGTLDRMLEKVANHYESDVDTLVDNLTSLMEPLIMVVLGGIVGALVVAMYLPVFQLGT
AF
MNDTPTIYAWEGINRKGRRVSGQIAGHNLALIKVQLRQQGICPERVRKKSCALPTFKTRITPVDIALFTRQLATLLKAGI
PLLQAFDIISEGVENPQLRELVKALKQHIASGHPLAAALRQYPRHFDELYCNLVAAGEMAGALETLLERVAIHLEKSQRL
KTRIKKAMTYPIAVLVIATGVSTVLLIHVVPQFQNLFAGVNGQLPGFTLGVIALSELLQQAWWMLGLGVGAALVAGRHAY
RTHPGFRHGWAAGLLKVPVAGKLLHKSAVARYARTLSTTFAAGVPLVQALGSVAGAVGHGPFKQAIERMRHDVSTGMQLN
QSMHNSGLFPGMAIQMTAIGEESGTLDRMLEKVANHYESDVDTLVDNLTSLMEPLIMVVLGGIVGALVVAMYLPVFQLGT
AF
Nucleotide
Download Length: 1209 bp
>NTDB_id=251002 CRN80_RS03705 WP_098949596.1 774810..776018(+) (pilC) [Pseudomonas sp. FDAARGOS_380]
ATGAACGACACTCCAACAATCTATGCCTGGGAGGGCATCAACCGCAAAGGGCGCCGGGTATCCGGGCAAATCGCCGGGCA
TAACCTTGCGCTGATCAAGGTACAACTTCGCCAGCAAGGGATCTGCCCCGAGCGTGTGCGCAAAAAATCTTGTGCACTGC
CAACCTTCAAGACGCGCATAACGCCTGTGGATATCGCCCTGTTCACTCGCCAGTTGGCCACCTTGCTCAAGGCCGGCATC
CCGCTGCTGCAAGCCTTCGACATCATCAGTGAAGGCGTCGAAAACCCACAGCTGCGCGAACTGGTGAAGGCGTTGAAACA
GCATATTGCCAGCGGCCACCCGTTGGCCGCTGCCCTGCGTCAGTATCCCCGCCACTTCGATGAGCTGTACTGCAATCTGG
TAGCGGCTGGCGAAATGGCCGGTGCCTTGGAAACCCTACTGGAGCGCGTGGCGATTCATCTGGAAAAAAGCCAACGGCTC
AAAACCAGGATCAAGAAAGCCATGACCTACCCTATCGCAGTACTGGTAATTGCCACAGGGGTGAGCACAGTGCTGTTGAT
CCATGTGGTGCCGCAATTCCAGAACTTGTTCGCCGGGGTCAACGGCCAATTGCCGGGGTTTACCTTGGGGGTCATCGCGC
TGTCGGAACTGCTGCAACAGGCGTGGTGGATGCTGGGGCTGGGTGTGGGCGCGGCGCTGGTTGCGGGGCGCCACGCCTAC
CGGACTCACCCGGGGTTTCGCCATGGGTGGGCAGCAGGTTTGTTGAAAGTGCCCGTGGCAGGCAAACTGCTGCACAAATC
TGCGGTCGCCCGCTACGCACGCACGCTATCCACTACCTTTGCGGCGGGCGTTCCTCTGGTACAGGCATTGGGTTCGGTGG
CTGGCGCCGTCGGTCATGGCCCCTTTAAACAGGCAATCGAACGTATGCGCCACGATGTATCCACAGGCATGCAGTTGAAT
CAATCGATGCATAACAGCGGCCTGTTCCCAGGCATGGCAATCCAGATGACCGCAATCGGTGAGGAGTCCGGCACCCTGGA
CCGCATGCTGGAAAAAGTCGCGAACCACTACGAGTCAGACGTGGACACCTTGGTCGACAACCTCACCAGCCTGATGGAGC
CGCTGATCATGGTGGTATTGGGGGGGATTGTCGGCGCGCTGGTAGTCGCCATGTACTTGCCGGTATTCCAATTGGGGACG
GCGTTTTGA
ATGAACGACACTCCAACAATCTATGCCTGGGAGGGCATCAACCGCAAAGGGCGCCGGGTATCCGGGCAAATCGCCGGGCA
TAACCTTGCGCTGATCAAGGTACAACTTCGCCAGCAAGGGATCTGCCCCGAGCGTGTGCGCAAAAAATCTTGTGCACTGC
CAACCTTCAAGACGCGCATAACGCCTGTGGATATCGCCCTGTTCACTCGCCAGTTGGCCACCTTGCTCAAGGCCGGCATC
CCGCTGCTGCAAGCCTTCGACATCATCAGTGAAGGCGTCGAAAACCCACAGCTGCGCGAACTGGTGAAGGCGTTGAAACA
GCATATTGCCAGCGGCCACCCGTTGGCCGCTGCCCTGCGTCAGTATCCCCGCCACTTCGATGAGCTGTACTGCAATCTGG
TAGCGGCTGGCGAAATGGCCGGTGCCTTGGAAACCCTACTGGAGCGCGTGGCGATTCATCTGGAAAAAAGCCAACGGCTC
AAAACCAGGATCAAGAAAGCCATGACCTACCCTATCGCAGTACTGGTAATTGCCACAGGGGTGAGCACAGTGCTGTTGAT
CCATGTGGTGCCGCAATTCCAGAACTTGTTCGCCGGGGTCAACGGCCAATTGCCGGGGTTTACCTTGGGGGTCATCGCGC
TGTCGGAACTGCTGCAACAGGCGTGGTGGATGCTGGGGCTGGGTGTGGGCGCGGCGCTGGTTGCGGGGCGCCACGCCTAC
CGGACTCACCCGGGGTTTCGCCATGGGTGGGCAGCAGGTTTGTTGAAAGTGCCCGTGGCAGGCAAACTGCTGCACAAATC
TGCGGTCGCCCGCTACGCACGCACGCTATCCACTACCTTTGCGGCGGGCGTTCCTCTGGTACAGGCATTGGGTTCGGTGG
CTGGCGCCGTCGGTCATGGCCCCTTTAAACAGGCAATCGAACGTATGCGCCACGATGTATCCACAGGCATGCAGTTGAAT
CAATCGATGCATAACAGCGGCCTGTTCCCAGGCATGGCAATCCAGATGACCGCAATCGGTGAGGAGTCCGGCACCCTGGA
CCGCATGCTGGAAAAAGTCGCGAACCACTACGAGTCAGACGTGGACACCTTGGTCGACAACCTCACCAGCCTGATGGAGC
CGCTGATCATGGTGGTATTGGGGGGGATTGTCGGCGCGCTGGTAGTCGCCATGTACTTGCCGGTATTCCAATTGGGGACG
GCGTTTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilC | Pseudomonas stutzeri DSM 10701 |
57.683 |
98.756 |
0.57 |
| pilC | Acinetobacter baumannii D1279779 |
50.754 |
99.005 |
0.502 |
| pilC | Acinetobacter baylyi ADP1 |
50.505 |
98.507 |
0.498 |
| pilC | Legionella pneumophila strain ERS1305867 |
47.761 |
100 |
0.478 |
| pilC | Vibrio cholerae strain A1552 |
39.949 |
97.761 |
0.391 |
| pilG | Neisseria gonorrhoeae MS11 |
39.791 |
95.025 |
0.378 |
| pilC | Thermus thermophilus HB27 |
37.75 |
99.502 |
0.376 |
| pilG | Neisseria meningitidis 44/76-A |
39.267 |
95.025 |
0.373 |
| pilC | Vibrio campbellii strain DS40M4 |
38.265 |
97.512 |
0.373 |