Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CO687_RS03565 Genome accession   NZ_CP023511
Coordinates   720483..721739 (+) Length   418 a.a.
NCBI ID   WP_045634772.1    Uniprot ID   A0AB35FWR5
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 715483..726739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS03535 (CO687_03535) - 716752..717273 (-) 522 WP_061596048.1 RDD family protein -
  CO687_RS03540 (CO687_03540) - 717257..717763 (-) 507 WP_045634808.1 helix-turn-helix transcriptional regulator -
  CO687_RS03545 (CO687_03545) ruvA 717931..718524 (+) 594 WP_045634768.1 Holliday junction branch migration protein RuvA -
  CO687_RS03550 (CO687_03550) - 718534..719088 (+) 555 WP_045634769.1 DNA-3-methyladenine glycosylase I -
  CO687_RS03555 (CO687_03555) - 719093..719752 (+) 660 WP_045634770.1 type II CAAX endopeptidase family protein -
  CO687_RS03560 (CO687_03560) - 719803..720213 (-) 411 WP_045634771.1 helix-turn-helix transcriptional regulator -
  CO687_RS03565 (CO687_03565) cinA 720483..721739 (+) 1257 WP_045634772.1 competence/damage-inducible protein A Machinery gene
  CO687_RS03570 (CO687_03570) recA 721798..722949 (+) 1152 WP_012131014.1 recombinase RecA Machinery gene
  CO687_RS03575 (CO687_03575) spx 723036..723434 (+) 399 WP_008809970.1 transcriptional regulator Spx -
  CO687_RS03580 (CO687_03580) - 723582..724154 (+) 573 WP_045634773.1 SP0191 family lipoprotein -
  CO687_RS03585 (CO687_03585) - 724266..724532 (+) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  CO687_RS03590 (CO687_03590) ruvX 724532..724951 (+) 420 WP_012131012.1 Holliday junction resolvase RuvX -
  CO687_RS03595 (CO687_03595) - 724973..725284 (+) 312 WP_008809966.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44736.69 Da        Isoelectric Point: 4.5259

>NTDB_id=247949 CO687_RS03565 WP_045634772.1 720483..721739(+) (cinA) [Streptococcus gordonii strain FDAARGOS_371]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELSFDPDAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLVEDNGVTYVVLPGPPSELKPM
VNNELVPILSTGQKLYSRVLRFFGIGESQLVTILSEMIDQQSDPTIAPYAKTGEVTLRLSTKALSQAEADTKFDAVEKEI
LSHKTFEDQSLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSRML
DIPLGELEEHGVVSAFTAGEMAEQARKLTESDLAVSLTGVAGPDSLEGHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=247949 CO687_RS03565 WP_045634772.1 720483..721739(+) (cinA) [Streptococcus gordonii strain FDAARGOS_371]
ATGAAAGCAGAAATTATTGCTGTGGGCACCGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
GAAACTGGCTAGTCTGGGGATTGATGTCTATTTTCAGACAGCTGTAGGGGACAATGAAAATCGTCTCCTCTCTATCCTAG
AGATTGCAAAAGGACGTAGTAATCTAATTATCTTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTAGGTCGAGAGTTGAGTTTCGACCCTGATGCTGTGGAAAAGTTGGATCGTTTTTTTGCCAGCCGACC
AGATTATGCTCGAACGCCCAACAATGAGCGTCAGGCCCAGCTAGTCGAAGGATCAACTCCTTTACCAAATGCGACTGGTT
TAGCTGTTGGCGGTTTAGTAGAAGATAATGGGGTGACTTATGTAGTTCTGCCTGGTCCGCCTAGCGAGCTCAAACCTATG
GTCAATAACGAGTTGGTTCCCATCTTATCCACAGGTCAAAAGTTGTACTCACGAGTGTTGCGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGATCAGCAAAGTGACCCCACCATTGCTCCTTATGCAAAGACAGGGG
AAGTTACCCTACGACTGTCCACCAAGGCCTTGAGTCAGGCAGAAGCCGACACCAAGTTTGATGCTGTGGAAAAGGAAATT
TTGTCACATAAGACTTTTGAAGACCAGTCTCTGTCAGAGATTTTCTATGGTTATGGGGATGACAATTCCTTGGCTCAGGT
GGCTTTTGACTTGCTCAAGAGTCAAGGAAAGACGATTTCAGCAGCAGAGAGTCTGACAGCAGGTCTCTTCCAAGCGACTT
TGGCAGATTTTGCTGGAGCTTCAGCTATTTTTTCAGGTGGCTTCGTCACCTATAGCATGGAGGAAAAGAGCCGGATGCTG
GACATTCCGCTGGGAGAGCTGGAGGAACATGGGGTTGTTTCAGCTTTTACGGCTGGGGAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTGGCTGTCAGTCTGACAGGCGTGGCTGGACCAGATTCACTGGAAGGCCATCCAGCAGGGACCG
TTTTTATCGGTTTAGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGTAGCCGGCGAGATGTACGA
AAAATCGCTGTTCTGCACGCCTTTAACCTAGTGCGAAAGACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.698

99.761

0.775
  cinA Streptococcus mitis NCTC 12261

77.218

99.761

0.77
  cinA Streptococcus pneumoniae TIGR4

76.739

99.761

0.766
  cinA Streptococcus pneumoniae Rx1

76.739

99.761

0.766
  cinA Streptococcus pneumoniae R6

76.739

99.761

0.766
  cinA Streptococcus pneumoniae D39

76.499

99.761

0.763
  cinA Streptococcus mutans UA159

74.402

100

0.744
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

100

0.469

Multiple sequence alignment