Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CO204_RS10245 Genome accession   NZ_CP023477
Coordinates   2013779..2015035 (-) Length   418 a.a.
NCBI ID   WP_106006865.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2008779..2020035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS10200 (CO204_10145) - 2008970..2009269 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  CO204_RS10205 (CO204_10150) ruvX 2009350..2009769 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  CO204_RS10210 (CO204_10155) - 2009766..2010035 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  CO204_RS10215 (CO204_10160) brsR 2010203..2010637 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  CO204_RS10220 (CO204_10165) brsM 2010650..2011096 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  CO204_RS10225 (CO204_10170) - 2011087..2011299 (-) 213 Protein_1928 hypothetical protein -
  CO204_RS10230 (CO204_10175) - 2011428..2011853 (-) 426 WP_002271571.1 hypothetical protein -
  CO204_RS10235 (CO204_10180) spx 2012105..2012503 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  CO204_RS10240 (CO204_10185) recA 2012588..2013739 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  CO204_RS10245 (CO204_10190) cinA 2013779..2015035 (-) 1257 WP_106006865.1 competence/damage-inducible protein A Machinery gene
  CO204_RS10250 (CO204_10195) - 2015184..2015744 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  CO204_RS10255 (CO204_10200) ruvA 2015826..2016419 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  CO204_RS10260 (CO204_10205) mutL 2016602..2018557 (-) 1956 WP_002268465.1 DNA mismatch repair endonuclease MutL -
  CO204_RS10265 (CO204_10210) - 2018782..2019060 (+) 279 Protein_1936 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45717.57 Da        Isoelectric Point: 6.7668

>NTDB_id=247454 CO204_RS10245 WP_106006865.1 2013779..2015035(-) (cinA) [Streptococcus mutans strain LAR01]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAKKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=247454 CO204_RS10245 WP_106006865.1 2013779..2015035(-) (cinA) [Streptococcus mutans strain LAR01]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTAAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.231

98.325

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment