Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CG712_RS06385 Genome accession   NZ_CP022547
Coordinates   1212331..1213602 (+) Length   423 a.a.
NCBI ID   WP_096811771.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1207331..1218602
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS06355 (CG712_06390) - 1207667..1208057 (-) 391 Protein_1212 LytTR family DNA-binding domain-containing protein -
  CG712_RS06360 (CG712_06395) - 1208281..1208586 (+) 306 WP_002949050.1 hypothetical protein -
  CG712_RS06365 (CG712_06400) mutL 1208638..1210581 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL -
  CG712_RS06370 (CG712_06405) - 1210711..1210932 (+) 222 WP_096811769.1 hypothetical protein -
  CG712_RS06375 (CG712_06410) ruvA 1211084..1211674 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  CG712_RS06380 (CG712_06415) - 1211681..1212235 (+) 555 Protein_1217 DNA-3-methyladenine glycosylase I -
  CG712_RS06385 (CG712_06420) cinA 1212331..1213602 (+) 1272 WP_096811771.1 competence/damage-inducible protein A Machinery gene
  CG712_RS06390 (CG712_06425) recA 1213638..1214777 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  CG712_RS06395 (CG712_06430) spx 1214954..1215352 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45958.30 Da        Isoelectric Point: 5.0971

>NTDB_id=240582 CG712_RS06385 WP_096811771.1 1212331..1213602(+) (cinA) [Streptococcus thermophilus strain B59671]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLHSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LDIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=240582 CG712_RS06385 WP_096811771.1 1212331..1213602(+) (cinA) [Streptococcus thermophilus strain B59671]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTCATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.702

99.054

0.74
  cinA Streptococcus mitis NCTC 12261

73.986

99.054

0.733
  cinA Streptococcus pneumoniae TIGR4

72.315

99.054

0.716
  cinA Streptococcus pneumoniae Rx1

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

72.076

99.054

0.714
  cinA Streptococcus pneumoniae D39

71.838

99.054

0.712
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.087

98.345

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment