Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CFA72_RS04765 Genome accession   NZ_CP022206
Coordinates   894011..894685 (+) Length   224 a.a.
NCBI ID   WP_010922355.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain GURSA1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 889011..899685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFA72_RS04745 (CFA72_04745) pstB 889444..890202 (+) 759 WP_002993892.1 phosphate ABC transporter ATP-binding protein PstB -
  CFA72_RS04750 (CFA72_04750) phoU 890270..890923 (+) 654 WP_002984514.1 phosphate signaling complex protein PhoU -
  CFA72_RS04760 (CFA72_04760) - 891128..893665 (+) 2538 WP_023610002.1 M1 family metallopeptidase -
  CFA72_RS04765 (CFA72_04765) ciaR 894011..894685 (+) 675 WP_010922355.1 response regulator transcription factor Regulator
  CFA72_RS04770 (CFA72_04770) ciaH 894678..895988 (+) 1311 WP_023610011.1 cell wall metabolism sensor histidine kinase WalK Regulator
  CFA72_RS04775 (CFA72_04775) rpsT 896113..896361 (-) 249 WP_172450286.1 30S ribosomal protein S20 -
  CFA72_RS04780 (CFA72_04780) coaA 896415..897335 (-) 921 WP_010922353.1 type I pantothenate kinase -
  CFA72_RS04785 (CFA72_04785) - 897603..898196 (+) 594 WP_010922352.1 class I SAM-dependent methyltransferase -
  CFA72_RS04790 (CFA72_04790) - 898849..899238 (+) 390 WP_002984531.1 cytidine deaminase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25650.86 Da        Isoelectric Point: 4.6480

>NTDB_id=237557 CFA72_RS04765 WP_010922355.1 894011..894685(+) (ciaR) [Streptococcus pyogenes strain GURSA1]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTCFVNRLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=237557 CFA72_RS04765 WP_010922355.1 894011..894685(+) (ciaR) [Streptococcus pyogenes strain GURSA1]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGCTTATCAAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
CATGCAAGTTTTTGATGGCGATGAAGGTTTATACGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGACCTTATGT
TGCCGGAGAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATCATGACAGCT
AAAGAGGGTTTAGATGATAAAGGTCACGGATTTGAATTAGGTGCTGATGATTATCTGACCAAGCCGTTCTATTTAGAAGA
GTTAAAAATGCGAATTCAAGCACTGTTAAAAAGAACAGGGAAATTTGCAGATAAAAATATTAGTTTTGGCAATTTAGTGG
TTGACTTAGCTCGAAAAGAGGTGAAGGTTGAAGGGAAAGTAGTTGAATTACTTGGCAAAGAATTTGATTTGTTGGTGTAT
CTTTTGCAAAATCAAAACGTTATTTTACCAAAGACACAAATTTTTGATCGTTTATGGGGATTCGATAGTGATACTACGAT
TTCGGTTGTTGAAGTTTACATTTCTAAAATAAGAAAAAAATTAAAAGGTACCTGTTTTGTTAACAGGCTTCAAACTTTAA
GAAGCGTAGGGTATATTCTAAAAAACAATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

85.135

99.107

0.844
  ciaR Streptococcus pneumoniae D39

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae R6

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae TIGR4

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae Rx1

84.685

99.107

0.839
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.111

100

0.393
  vicR Streptococcus mutans UA159

35.897

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.47

100

0.371
  covR Streptococcus salivarius strain HSISS4

36.283

100

0.366

Multiple sequence alignment