Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CCE29_RS02610 Genome accession   NZ_CP021426
Coordinates   487672..488913 (-) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain 4B15     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 447942..496829 487672..488913 within 0


Gene organization within MGE regions


Location: 447942..496829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCE29_RS02420 (CCE29_02410) - 448228..448767 (-) 540 WP_014569370.1 HdeD family acid-resistance protein -
  CCE29_RS02425 (CCE29_02415) uvrA 448969..451863 (-) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  CCE29_RS02430 (CCE29_02420) uvrB 452044..454059 (-) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  CCE29_RS02435 (CCE29_02425) - 454330..454977 (-) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  CCE29_RS02440 (CCE29_02430) - 455437..457164 (-) 1728 WP_014569367.1 phospho-sugar mutase -
  CCE29_RS02445 (CCE29_02435) trxB 457416..458363 (-) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  CCE29_RS02450 (CCE29_02440) - 458429..459484 (-) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  CCE29_RS02455 (CCE29_02445) lgt 459495..460322 (-) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  CCE29_RS02460 (CCE29_02450) hprK 460324..461283 (-) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  CCE29_RS02465 (CCE29_02455) - 461550..461885 (-) 336 WP_005684507.1 phage holin family protein -
  CCE29_RS02470 (CCE29_02460) - 461888..462148 (-) 261 WP_005688700.1 hypothetical protein -
  CCE29_RS02475 (CCE29_02465) liaX 462160..463650 (-) 1491 WP_014569364.1 daptomycin-sensing surface protein LiaX -
  CCE29_RS02480 (CCE29_02470) - 464219..464947 (+) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  CCE29_RS02485 (CCE29_02475) - 464944..465822 (+) 879 WP_048653158.1 IS3 family transposase -
  CCE29_RS02490 (CCE29_02480) phoU 466076..466753 (-) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  CCE29_RS02495 (CCE29_02485) pstB 466764..467528 (-) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  CCE29_RS02500 (CCE29_02490) pstB 467538..468356 (-) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  CCE29_RS02505 (CCE29_02495) pstA 468427..469311 (-) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  CCE29_RS02510 (CCE29_02500) pstC 469308..470231 (-) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  CCE29_RS02515 (CCE29_02505) - 470379..471245 (-) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  CCE29_RS02520 (CCE29_02510) pnpS 471335..473002 (-) 1668 WP_014569361.1 two-component system histidine kinase PnpS -
  CCE29_RS02525 (CCE29_02515) - 472995..473699 (-) 705 WP_005688690.1 response regulator transcription factor -
  CCE29_RS02530 (CCE29_02520) - 473696..474793 (-) 1098 WP_014569360.1 PDZ domain-containing protein -
  CCE29_RS15780 - 474849..474986 (-) 138 WP_014569359.1 hypothetical protein -
  CCE29_RS02535 (CCE29_02525) ftsX 475064..475951 (-) 888 WP_005684490.1 permease-like cell division protein FtsX -
  CCE29_RS02540 (CCE29_02530) ftsE 475941..476627 (-) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  CCE29_RS02550 (CCE29_02540) secA 477962..480325 (-) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  CCE29_RS02565 (CCE29_02555) hpf 480908..481465 (-) 558 WP_005684485.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  CCE29_RS02570 (CCE29_02560) - 481657..482175 (-) 519 WP_005688681.1 ComF family protein -
  CCE29_RS02575 (CCE29_02565) - 482334..483599 (-) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  CCE29_RS02580 (CCE29_02570) - 483627..484283 (+) 657 WP_029943817.1 YigZ family protein -
  CCE29_RS02585 (CCE29_02575) rny 484372..485943 (-) 1572 WP_005684479.1 ribonuclease Y -
  CCE29_RS02605 (CCE29_02595) recA 486568..487620 (-) 1053 WP_005688187.1 recombinase RecA Machinery gene
  CCE29_RS02610 (CCE29_02600) cinA 487672..488913 (-) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  CCE29_RS02615 (CCE29_02605) pgsA 489134..489724 (-) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CCE29_RS02620 (CCE29_02610) - 489721..490656 (-) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  CCE29_RS02625 (CCE29_02615) ymfI 490743..491471 (-) 729 WP_014569350.1 elongation factor P 5-aminopentanone reductase -
  CCE29_RS02630 (CCE29_02620) yfmH 491471..492763 (-) 1293 WP_014569349.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  CCE29_RS02635 (CCE29_02625) yfmF 492760..494022 (-) 1263 WP_014569348.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  CCE29_RS02640 (CCE29_02630) - 494031..496331 (-) 2301 WP_014569347.1 DNA translocase FtsK -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=230604 CCE29_RS02610 WP_014569352.1 487672..488913(-) (cinA) [Lacticaseibacillus rhamnosus strain 4B15]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=230604 CCE29_RS02610 WP_014569352.1 487672..488913(-) (cinA) [Lacticaseibacillus rhamnosus strain 4B15]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39

Multiple sequence alignment