Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CA921_RS07195 Genome accession   NZ_CP021283
Coordinates   1587858..1589078 (+) Length   406 a.a.
NCBI ID   WP_027265236.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Allentown     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1582858..1594078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA921_RS07175 - 1584005..1584574 (-) 570 WP_011215552.1 hypoxanthine-guanine phosphoribosyltransferase -
  CA921_RS07180 - 1584617..1584943 (-) 327 WP_011213802.1 DUF1820 family protein -
  CA921_RS07185 - 1585126..1585869 (-) 744 WP_061692569.1 methyltransferase domain-containing protein -
  CA921_RS07190 pilB 1586128..1587852 (+) 1725 WP_027265235.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CA921_RS07195 pilC 1587858..1589078 (+) 1221 WP_027265236.1 type II secretion system F family protein Machinery gene
  CA921_RS07200 pilD 1589124..1589987 (+) 864 WP_061692570.1 prepilin peptidase Machinery gene
  CA921_RS07205 - 1590001..1591206 (-) 1206 WP_061692571.1 cyclic nucleotide-binding domain-containing protein -
  CA921_RS07210 - 1591314..1591907 (-) 594 WP_027265239.1 hypothetical protein -
  CA921_RS07215 - 1591923..1592378 (-) 456 WP_010947256.1 hypothetical protein -
  CA921_RS07220 ppsR 1592512..1593327 (+) 816 WP_010947257.1 posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44711.85 Da        Isoelectric Point: 9.6052

>NTDB_id=229669 CA921_RS07195 WP_027265236.1 1587858..1589078(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Allentown]
MDKNSPTLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVIKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGVVYSF
FYAKNHSLEFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFTAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=229669 CA921_RS07195 WP_027265236.1 1587858..1589078(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Allentown]
ATGGATAAAAATAGCCCAACCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAATAAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACTGTATTTAGCCGCCAATTAGCGACGATGATC
GAGTCAGGAATACCATTAGTACAAGCATTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTGGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGTGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTACCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
GGGATTATTAATCTATGTGGTTCCTCAATTTGAATCATTATTTAAAGGATTTGGAGCTGATTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAGCTTTGGGAGGGGTTGTCTATAGCTTT
TTTTATGCTAAAAATCATTCTTTGGAGTTTGCGCAAACCATTGACAGAGTGATGCTAAAATTCCCTGTAATTGGTCCTAT
TTTAGAGAAAGCAGCAATTGCTAGATTCGCAAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACCGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGAGAAGAAGTTGCAACAGGA
CAGCAAATGTTTACTGCTATGGAAAATACTCATTTATTTCCAAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTGAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTAGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.015

100

0.99
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.58

99.754

0.534
  pilC Acinetobacter baylyi ADP1

52.84

99.754

0.527
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

41.855

98.276

0.411
  pilC Vibrio campbellii strain DS40M4

38.916

100

0.389

Multiple sequence alignment