Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CA924_RS07355 Genome accession   NZ_CP021281
Coordinates   1597128..1598348 (+) Length   406 a.a.
NCBI ID   WP_011213805.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Flint     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1592128..1603348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA924_RS07335 - 1593276..1593845 (-) 570 WP_011213801.1 hypoxanthine-guanine phosphoribosyltransferase -
  CA924_RS07340 - 1593888..1594214 (-) 327 WP_011213802.1 DUF1820 family protein -
  CA924_RS07345 - 1594397..1595140 (-) 744 WP_011213803.1 methyltransferase domain-containing protein -
  CA924_RS07350 pilB 1595399..1597122 (+) 1724 Protein_1415 type IV-A pilus assembly ATPase PilB -
  CA924_RS07355 pilC 1597128..1598348 (+) 1221 WP_011213805.1 type II secretion system F family protein Machinery gene
  CA924_RS07360 pilD 1598394..1599257 (+) 864 WP_011213806.1 A24 family peptidase Machinery gene
  CA924_RS07365 - 1599271..1600476 (-) 1206 WP_011213807.1 cyclic nucleotide-binding domain-containing protein -
  CA924_RS07370 - 1600584..1601177 (-) 594 WP_011213808.1 hypothetical protein -
  CA924_RS07375 - 1601193..1601648 (-) 456 WP_011213809.1 hypothetical protein -
  CA924_RS07380 - 1601782..1602597 (+) 816 WP_011213810.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44671.88 Da        Isoelectric Point: 9.6052

>NTDB_id=229629 CA924_RS07355 WP_011213805.1 1597128..1598348(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Flint]
MDKNSPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGVVYSF
FYAKNHSLEFAQTIDRVMLKLPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFIAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=229629 CA924_RS07355 WP_011213805.1 1597128..1598348(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Flint]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGTTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAGTAAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACAGTGTTTAGCCGTCAATTAGCGACGATGATC
GAGTCTGGAATACCATTAGTGCAAGCGTTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTAGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGCGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTACCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
AGGATTATTAATCTATGTAGTTCCTCAATTTGAATCGTTGTTTAAAGGATTTGGAGCTGATTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAGCTTTGGGTGGGGTTGTCTATAGCTTT
TTTTATGCTAAAAATCATTCTTTGGAGTTTGCACAAACCATTGACAGAGTGATGCTAAAACTCCCTGTAATTGGCCCTAT
TTTAGAGAAAGCAGCAATTGCTCGATTCGCGAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACTGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGAGAAGAAGTTGCAACAGGA
CAGCAAATGTTTATTGCTATGGAAAACACTCATTTATTTCCGAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTAAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

100

100

1
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.827

99.754

0.537
  pilC Acinetobacter baylyi ADP1

53.086

99.754

0.53
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42

98.522

0.414
  pilC Vibrio campbellii strain DS40M4

39.163

100

0.392

Multiple sequence alignment