Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   B6N58_RS07980 Genome accession   NZ_CP020614
Coordinates   1771449..1772657 (+) Length   402 a.a.
NCBI ID   WP_349267104.1    Uniprot ID   A0A098GEC2
Organism   Legionella micdadei strain NZ2015     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1766449..1777657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6N58_RS07960 (B6N58_07960) - 1767769..1768329 (-) 561 WP_045099176.1 hypoxanthine-guanine phosphoribosyltransferase -
  B6N58_RS07965 (B6N58_07965) - 1768356..1768682 (-) 327 WP_045099175.1 DUF1820 family protein -
  B6N58_RS07970 (B6N58_07970) - 1768795..1769574 (-) 780 WP_045099174.1 methyltransferase domain-containing protein -
  B6N58_RS07975 (B6N58_07975) pilB 1769740..1771446 (+) 1707 WP_045099173.1 type IV-A pilus assembly ATPase PilB Machinery gene
  B6N58_RS07980 (B6N58_07980) pilC 1771449..1772657 (+) 1209 WP_349267104.1 type II secretion system F family protein Machinery gene
  B6N58_RS07985 (B6N58_07985) - 1772661..1773515 (+) 855 WP_045099172.1 A24 family peptidase -
  B6N58_RS07990 (B6N58_07990) - 1773561..1774703 (+) 1143 WP_045099171.1 hypothetical protein -
  B6N58_RS07995 (B6N58_07995) - 1775043..1775627 (-) 585 WP_045099170.1 hypothetical protein -
  B6N58_RS08000 (B6N58_08000) - 1775697..1776143 (-) 447 WP_045099169.1 hypothetical protein -
  B6N58_RS08005 (B6N58_08005) - 1776380..1777195 (+) 816 WP_045099168.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 45053.59 Da        Isoelectric Point: 9.6685

>NTDB_id=224963 B6N58_RS07980 WP_349267104.1 1771449..1772657(+) (pilC) [Legionella micdadei strain NZ2015]
MMNKTKHCYYWEGINALGEKVHGLMDTTSTAFVKVELHKQGISSRKITKKQSLFLNRKKIRPIELASFCRQTAILLKAGI
PLIRSFDIVAKSQIRLTMKYLIQDIKMQVENGLSFSEALNHYPNIFNELTCNLISVGEKTGNLEPMLETLANYKEKLETI
KRKLKKALIYPATVLFIACLVSFILLFVVVPQFESLFESFGADLPPLTRAVIQISTLSRAIGLPIFLGAISLGYSFFKLR
KYVPELNLFFDRLSLKCPIFGVILTKAIIARFSQTLAVSFAAGLPLFNALDAAEGVIANWIYAKAISQIKEKVYSGQQMN
QAMENTLLFPNLVIQMIAIGEEAGSLEPMLRKIADFYEEDISNAVDRLNHLLEPVIMTILGLIVGILVTAMYLPIFKLGA
VM

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=224963 B6N58_RS07980 WP_349267104.1 1771449..1772657(+) (pilC) [Legionella micdadei strain NZ2015]
ATGATGAATAAAACTAAGCACTGTTATTATTGGGAAGGGATCAATGCATTGGGTGAAAAGGTACATGGTCTCATGGATAC
TACCAGCACCGCTTTCGTGAAAGTCGAGCTTCATAAACAGGGTATCAGTAGTCGAAAGATAACAAAAAAACAGAGTTTAT
TTTTGAATAGAAAAAAAATTCGCCCAATTGAACTCGCTAGTTTTTGTCGCCAGACTGCCATCTTACTTAAAGCGGGAATT
CCTTTAATTCGATCGTTTGATATCGTTGCTAAAAGCCAAATTCGGCTTACAATGAAATACTTGATTCAAGACATAAAAAT
GCAAGTTGAAAATGGATTATCTTTTTCTGAAGCCCTAAATCATTACCCAAACATATTCAATGAATTAACTTGCAATTTAA
TTTCCGTAGGTGAAAAAACCGGCAACCTTGAGCCAATGCTCGAAACTCTCGCGAATTACAAAGAAAAATTAGAAACAATC
AAGAGAAAACTAAAAAAAGCACTCATCTATCCTGCTACCGTTTTATTTATTGCTTGTCTAGTTAGTTTCATACTTTTGTT
CGTTGTTGTTCCCCAATTTGAGTCGTTGTTTGAGAGTTTTGGTGCCGATCTCCCTCCACTTACACGTGCAGTCATTCAAA
TCTCAACATTGAGCAGAGCAATTGGATTACCAATTTTTTTGGGTGCCATTAGCTTAGGCTATAGCTTTTTTAAACTTAGA
AAATATGTGCCAGAATTAAATCTTTTTTTTGATCGGCTTTCCTTAAAATGTCCCATTTTTGGCGTTATCTTAACAAAAGC
AATTATCGCACGTTTTTCTCAAACATTAGCGGTTAGTTTTGCAGCTGGTCTTCCACTTTTTAATGCGCTCGATGCTGCGG
AGGGAGTCATAGCAAACTGGATATATGCTAAAGCGATTAGCCAAATCAAAGAGAAGGTTTATTCAGGACAACAAATGAAT
CAAGCCATGGAAAATACCCTTCTTTTTCCTAATTTAGTAATTCAAATGATTGCTATTGGCGAGGAGGCAGGTTCACTGGA
ACCGATGCTCCGCAAAATAGCTGATTTTTATGAAGAAGACATTAGCAACGCGGTAGATCGCTTAAATCACTTGCTAGAGC
CGGTTATTATGACAATACTAGGGTTAATCGTCGGTATCCTAGTAACAGCCATGTATCTTCCTATCTTTAAACTTGGAGCG
GTGATGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(68-191)

Type II secretion system (T2SS), protein F (T2SSF)

(272-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098GEC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

52.393

98.756

0.517
  pilC Acinetobacter baylyi ADP1

45

99.502

0.448
  pilC Pseudomonas stutzeri DSM 10701

44.332

98.756

0.438
  pilC Acinetobacter baumannii D1279779

43.719

99.005

0.433
  pilG Neisseria gonorrhoeae MS11

38.958

100

0.391
  pilC Vibrio cholerae strain A1552

39.141

98.507

0.386
  pilC Vibrio campbellii strain DS40M4

38.889

98.507

0.383
  pilG Neisseria meningitidis 44/76-A

38.213

100

0.383

Multiple sequence alignment