Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GBS_RS10640 Genome accession   NC_004368
Coordinates   2120661..2121920 (-) Length   419 a.a.
NCBI ID   WP_001200977.1    Uniprot ID   Q8E2R9
Organism   Streptococcus agalactiae NEM316     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2115661..2126920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBS_RS10605 (gbs2042) - 2115813..2117354 (-) 1542 WP_000230040.1 membrane protein -
  GBS_RS11905 - 2117400..2117522 (-) 123 WP_001285711.1 hypothetical protein -
  GBS_RS10615 (gbs2043) - 2117604..2117921 (-) 318 WP_000940932.1 DUF1292 domain-containing protein -
  GBS_RS10620 (gbs2044) ruvX 2117947..2118366 (-) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  GBS_RS10625 (gbs2045) - 2118366..2118632 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  GBS_RS10630 spx 2118834..2119232 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  GBS_RS10635 (gbs2047) recA 2119448..2120587 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  GBS_RS10640 (gbs2048) cinA 2120661..2121920 (-) 1260 WP_001200977.1 competence/damage-inducible protein A Machinery gene
  GBS_RS10645 (gbs2049) - 2122009..2122560 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  GBS_RS10650 (gbs2050) ruvA 2122583..2123173 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA -
  GBS_RS10655 (gbs2051) - 2123175..2124407 (-) 1233 WP_000657476.1 MFS transporter -
  GBS_RS10660 (gbs2052) mutL 2124439..2126412 (-) 1974 WP_000034617.1 DNA mismatch repair endonuclease MutL -
  GBS_RS10665 (gbs2053) - 2126638..2126841 (+) 204 WP_000191849.1 cold-shock protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45482.34 Da        Isoelectric Point: 6.3076

>NTDB_id=22482 GBS_RS10640 WP_001200977.1 2120661..2121920(-) (cinA) [Streptococcus agalactiae NEM316]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQLVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASRKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELKPM
VMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVVSHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDLVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=22482 GBS_RS10640 WP_001200977.1 2120661..2121920(-) (cinA) [Streptococcus agalactiae NEM316]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGACAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAATTGGTTATCCTATGTGGTGGACTTGGCCCTACAGAGGATGACTTAACGAAGCAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTAGATTTATTAGCTAGTCGAAAATTGGATCGTTTTTTTGCAAGTCGTCC
TCAGTTTGCTAGAACGCCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAAGCCAATG
GTTATGGAGCAGGTAGTACCTATTTTGTCAAATAATGGCACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATCGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGACCCAACTATAGCACCATATGCAAAGGTTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGGATGAGGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGTTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGTTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTGTCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAACTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGTCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACTTGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E2R9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.703

99.523

0.714
  cinA Streptococcus mitis NCTC 12261

71.463

99.523

0.711
  cinA Streptococcus pneumoniae TIGR4

70.264

99.523

0.699
  cinA Streptococcus pneumoniae Rx1

70.264

99.523

0.699
  cinA Streptococcus pneumoniae R6

70.264

99.523

0.699
  cinA Streptococcus pneumoniae D39

70.024

99.523

0.697
  cinA Streptococcus mutans UA159

68.345

99.523

0.68
  cinA Streptococcus suis isolate S10

54.808

99.284

0.544
  cinA Bacillus subtilis subsp. subtilis str. 168

43.541

99.761

0.434

Multiple sequence alignment