Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilG   Type   Machinery gene
Locus tag   A6J88_RS19810 Genome accession   NZ_CP020452
Coordinates   1126115..1127356 (+) Length   413 a.a.
NCBI ID   WP_060974403.1    Uniprot ID   A0A1V0HD61
Organism   Neisseria mucosa strain FDAARGOS_260     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1121115..1132356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J88_RS19785 (A6J88_05700) - 1121593..1122339 (+) 747 WP_240594061.1 hypothetical protein -
  A6J88_RS19795 (A6J88_05710) - 1123202..1123549 (+) 348 WP_240594077.1 YadA C-terminal domain-containing protein -
  A6J88_RS19800 (A6J88_05715) - 1123617..1124084 (+) 468 WP_049226372.1 outer membrane protein assembly factor BamE -
  A6J88_RS19805 (A6J88_05720) pilF 1124364..1126043 (+) 1680 WP_060974402.1 type IV-A pilus assembly ATPase PilB Machinery gene
  A6J88_RS19810 (A6J88_05725) pilG 1126115..1127356 (+) 1242 WP_060974403.1 type II secretion system F family protein Machinery gene
  A6J88_RS19815 (A6J88_05730) pilD 1127358..1128221 (+) 864 WP_080613751.1 prepilin peptidase Machinery gene
  A6J88_RS19820 (A6J88_05735) coaE 1128223..1128852 (+) 630 WP_080613752.1 dephospho-CoA kinase -
  A6J88_RS19825 (A6J88_05740) yacG 1128907..1129101 (+) 195 WP_045074220.1 DNA gyrase inhibitor YacG -
  A6J88_RS19830 (A6J88_05745) ribF 1129203..1130132 (-) 930 WP_080613753.1 bifunctional riboflavin kinase/FAD synthetase -
  A6J88_RS19835 (A6J88_05750) - 1130237..1130629 (-) 393 WP_080613754.1 hypothetical protein -
  A6J88_RS19840 (A6J88_05755) ispH 1130774..1131742 (-) 969 WP_080613755.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  A6J88_RS19845 (A6J88_05760) lspA 1131769..1132287 (-) 519 WP_080613756.1 signal peptidase II -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45807.73 Da        Isoelectric Point: 9.9286

>NTDB_id=223302 A6J88_RS19810 WP_060974403.1 1126115..1127356(+) (pilG) [Neisseria mucosa strain FDAARGOS_260]
MAQAEQKRGLFAQKNKGKRFTFEGKNTNTDQLVRGEVVAKDEEEARKKLQRRGIRPLRISKVKATKKRRITQEDITVFTR
QLATMMKAGLPLMQAFEIVARGHSNPSMTEMLMQVRADVEQGSALGKSFAKYPKYFDRFYCNLIAAGETGGVLESLLDKL
AVYKEKTQAIKKKVKTALTYPISIVVVAVVLIFVMMRWVLPAFKEVYSNMGAELPGMTQTVMSISDFFVEYGWIMIIAAI
GIGFGVYKLHQKSPEFQKRVDAMVLRMPIFGSIIRKATIARWARTTSTLFAAGVPLVEVLDSVSGAAGNILYEEATQDIR
AKVTQGLSLTSSMQSTDMFPNMVIQMAAIGEESGSLDDMLNKAAEFYEEEVDNSVSQLSSLMEPIIMVVLGSIIGTILVA
MYLPLFNLGNVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=223302 A6J88_RS19810 WP_060974403.1 1126115..1127356(+) (pilG) [Neisseria mucosa strain FDAARGOS_260]
ATGGCTCAAGCAGAGCAAAAAAGAGGCTTATTCGCTCAAAAAAATAAAGGCAAACGTTTTACGTTTGAAGGTAAAAATAC
CAATACGGATCAATTAGTCCGAGGCGAAGTAGTCGCCAAAGACGAAGAAGAAGCGCGTAAAAAGCTCCAACGCCGCGGGA
TACGCCCTTTACGTATCAGTAAAGTAAAGGCAACCAAAAAGCGTCGTATTACTCAGGAAGACATTACAGTTTTCACCCGT
CAACTCGCCACCATGATGAAAGCAGGTCTGCCTTTAATGCAGGCTTTTGAAATTGTCGCACGCGGACACTCCAACCCATC
CATGACTGAAATGTTGATGCAAGTCCGTGCAGATGTGGAACAAGGTAGTGCATTAGGTAAATCATTTGCCAAATACCCAA
AATATTTCGACCGTTTTTATTGCAATCTGATTGCGGCTGGCGAGACCGGTGGTGTTTTAGAAAGCCTGTTGGATAAACTT
GCTGTATATAAAGAGAAAACACAAGCCATTAAGAAAAAAGTAAAAACTGCATTGACGTACCCAATTTCTATTGTGGTTGT
TGCGGTTGTACTGATTTTCGTAATGATGCGCTGGGTTTTGCCTGCATTTAAAGAGGTTTACTCCAATATGGGAGCAGAAT
TACCAGGTATGACACAAACAGTCATGAGTATTTCCGACTTTTTTGTGGAATATGGCTGGATCATGATTATTGCAGCAATT
GGCATTGGATTTGGTGTATATAAATTGCATCAGAAATCTCCTGAATTTCAAAAACGTGTAGATGCCATGGTTTTACGTAT
GCCTATTTTTGGCTCTATCATTCGTAAAGCAACTATTGCACGTTGGGCTCGTACTACTTCTACCTTATTTGCCGCAGGTG
TCCCTTTAGTAGAAGTTTTAGATTCTGTATCAGGTGCTGCTGGCAATATACTCTATGAAGAAGCAACGCAAGACATCCGT
GCAAAAGTTACTCAAGGTCTCTCTTTGACTTCAAGTATGCAAAGTACGGATATGTTTCCGAATATGGTTATTCAAATGGC
CGCTATTGGTGAAGAATCTGGATCCCTTGATGATATGCTGAATAAGGCTGCTGAATTTTATGAGGAAGAAGTTGATAACT
CTGTATCACAACTATCTTCTCTGATGGAGCCGATTATTATGGTGGTTTTGGGCTCCATTATCGGTACAATCCTGGTAGCA
ATGTATCTGCCGCTGTTTAACCTCGGTAACGTAGTAGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(78-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0HD61

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilG Neisseria gonorrhoeae MS11

71.921

98.305

0.707
  pilG Neisseria meningitidis 44/76-A

71.429

98.305

0.702
  pilC Legionella pneumophila strain ERS1305867

46.173

98.063

0.453
  pilC Pseudomonas stutzeri DSM 10701

43.704

98.063

0.429
  pilC Acinetobacter baylyi ADP1

44.361

96.61

0.429
  pilC Acinetobacter baumannii D1279779

44.472

96.368

0.429
  pilC Vibrio cholerae strain A1552

38

96.852

0.368

Multiple sequence alignment