Detailed information NTG0223216

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: A6J87_RS00160
• Genome accession: NZ_CP020451
• Coordinates: 28619..29326 (-)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 23619..34326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS00135 (A6J87_00135)	yidA	23973..24782 (+)	810	WP_080611392.1	sugar-phosphatase	-
A6J87_RS00140 (A6J87_00140)	-	24784..25998 (+)	1215	WP_080611393.1	aminoacyltransferase	-
A6J87_RS00145 (A6J87_00145)	-	26050..26409 (-)	360	WP_045769141.1	YbaN family protein	-
A6J87_RS00150 (A6J87_00150)	vicX	26468..27280 (-)	813	WP_080612056.1	MBL fold metallo-hydrolase	Regulator
A6J87_RS00155 (A6J87_00155)	vicK	27286..28626 (-)	1341	WP_080611394.1	cell wall metabolism sensor histidine kinase VicK	Regulator
A6J87_RS00160 (A6J87_00160)	vicR	28619..29326 (-)	708	WP_002884978.1	response regulator YycF	Regulator
A6J87_RS00165 (A6J87_00165)	-	29612..30379 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-
A6J87_RS00170 (A6J87_00170)	-	30389..31222 (+)	834	WP_080611395.1	transporter substrate-binding domain-containing protein	-
A6J87_RS00175 (A6J87_00175)	-	31240..31938 (+)	699	WP_080611396.1	amino acid ABC transporter permease	-
A6J87_RS00180 (A6J87_00180)	-	31950..32600 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
A6J87_RS00185 (A6J87_00185)	endA	32677..33558 (-)	882	WP_013990683.1	DNA/RNA non-specific endonuclease	Machinery gene
A6J87_RS00190 (A6J87_00190)	-	33620..33808 (-)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=223216 A6J87_RS00160 WP_002884978.1 28619..29326(-) (vicR) [Streptococcus salivarius strain FDAARGOS_259]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=223216 A6J87_RS00160 WP_002884978.1 28619..29326(-) (vicR) [Streptococcus salivarius strain FDAARGOS_259]
ATGAAAAAAATTCTTGTTGTTGATGATGAAAGACCAATTTCGGATATCATCAAGTTTAATCTGACTAAAGAAGGTTATGA
AGTGGTTACGGCCTTTGATGGTCGTGAAGCATTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGCTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAGATTTCAATTGGGGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAACTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACTCGTGAACATTTGCTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGACA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387