Detailed information NTG0223217

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: A6J87_RS00185
• Genome accession: NZ_CP020451
• Coordinates: 32677..33558 (-)
• Length: 293 a.a.
• NCBI ID: WP_013990683.1
• Uniprot ID: A0AB33ZCG3
• Organism: Streptococcus salivarius strain FDAARGOS_259
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 27677..38558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J87_RS00160 (A6J87_00160)	vicR	28619..29326 (-)	708	WP_002884978.1	response regulator YycF	Regulator
A6J87_RS00165 (A6J87_00165)	-	29612..30379 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-
A6J87_RS00170 (A6J87_00170)	-	30389..31222 (+)	834	WP_080611395.1	transporter substrate-binding domain-containing protein	-
A6J87_RS00175 (A6J87_00175)	-	31240..31938 (+)	699	WP_080611396.1	amino acid ABC transporter permease	-
A6J87_RS00180 (A6J87_00180)	-	31950..32600 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
A6J87_RS00185 (A6J87_00185)	endA	32677..33558 (-)	882	WP_013990683.1	DNA/RNA non-specific endonuclease	Machinery gene
A6J87_RS00190 (A6J87_00190)	-	33620..33808 (-)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
A6J87_RS00195 (A6J87_00195)	murA	33810..35081 (-)	1272	WP_064525319.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
A6J87_RS00200 (A6J87_00200)	-	35149..35385 (-)	237	WP_004182616.1	DUF1146 family protein	-
A6J87_RS00205 (A6J87_00205)	-	35656..36759 (-)	1104	WP_004182617.1	glycosyl hydrolase family 8	-
A6J87_RS00210 (A6J87_00210)	-	36768..38078 (-)	1311	WP_004182618.1	glycosyltransferase	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31476.06 Da
• Isoelectric Point: 10.2177

>NTDB_id=223217 A6J87_RS00185 WP_013990683.1 32677..33558(-) (endA) [Streptococcus salivarius strain FDAARGOS_259]
MAKRKTSLTNKQKRQLVSLLIAVLIAVLGYIGTSNKLSPNNPIKQVASLVSGKSNNSAKSNGSTSGQSTPQEQLAETVMT
SSVKSQLGNAIEWNGAGAYIVNGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVHNLSGEYSHAVDRGHLLGYALVGGLKGFDASTSNPENIAVQTAWANQANSETSTGQNYYESLVRKAQDKNKRVR
YRVTLIYEGDNLIPSGSHLEAKSADGSLEFNVFVPNVQQGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=223217 A6J87_RS00185 WP_013990683.1 32677..33558(-) (endA) [Streptococcus salivarius strain FDAARGOS_259]
ATGGCAAAAAGAAAGACATCTTTAACAAATAAACAGAAACGTCAGCTAGTCTCGTTACTAATAGCGGTTTTGATTGCAGT
TTTAGGTTACATTGGAACGAGTAATAAGCTCTCACCTAACAATCCAATCAAGCAGGTAGCTAGTCTAGTCTCGGGAAAAT
CCAATAACTCCGCCAAATCAAACGGCTCAACAAGTGGGCAGTCTACGCCACAAGAGCAACTCGCAGAGACGGTGATGACT
AGCTCTGTCAAGAGTCAACTAGGAAACGCCATAGAATGGAATGGGGCTGGTGCCTATATTGTTAACGGTAATAAAACCAA
TCTTAATGCTAAGGTATCTAGCCAACCCTACGCTAATAACCAAGTTAAAACGGTTCAAGGACAAACGGTTCCTACAGTTG
CGAATGCCTTGTTAAGTAAAGCGACCAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGCTCAACTTCTTGGACACCA
GCTGGATGGCATCAAGTTCACAATCTTTCAGGAGAGTATAGCCATGCCGTAGACCGAGGCCATTTGTTAGGTTATGCACT
TGTAGGTGGTCTCAAAGGATTTGATGCCTCGACTTCAAATCCAGAAAATATTGCCGTTCAAACTGCTTGGGCTAACCAAG
CTAATAGCGAAACTTCCACAGGCCAAAACTATTATGAAAGCCTGGTACGAAAAGCTCAAGATAAAAATAAACGTGTCCGT
TATCGCGTTACCCTCATTTATGAAGGAGATAACCTGATTCCATCAGGATCACATCTTGAAGCCAAGTCAGCAGATGGCTC
GCTTGAGTTCAACGTCTTCGTTCCAAATGTCCAACAGGGAATTACCCTAGATTATTATTCAGGGAAAGTAACGGTGAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.356	86.348	0.608
endA	Streptococcus pneumoniae D39	70.356	86.348	0.608
endA	Streptococcus pneumoniae R6	70.356	86.348	0.608
endA	Streptococcus pneumoniae TIGR4	70.356	86.348	0.608