Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   A6J87_RS00155 Genome accession   NZ_CP020451
Coordinates   27286..28626 (-) Length   446 a.a.
NCBI ID   WP_080611394.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 22286..33626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS00125 (A6J87_00125) - 22459..22845 (-) 387 WP_002884910.1 DUF1934 domain-containing protein -
  A6J87_RS00130 (A6J87_00130) - 22937..23794 (-) 858 WP_073951140.1 GNAT family N-acetyltransferase -
  A6J87_RS00135 (A6J87_00135) yidA 23973..24782 (+) 810 WP_080611392.1 sugar-phosphatase -
  A6J87_RS00140 (A6J87_00140) - 24784..25998 (+) 1215 WP_080611393.1 aminoacyltransferase -
  A6J87_RS00145 (A6J87_00145) - 26050..26409 (-) 360 WP_045769141.1 YbaN family protein -
  A6J87_RS00150 (A6J87_00150) vicX 26468..27280 (-) 813 WP_080612056.1 MBL fold metallo-hydrolase Regulator
  A6J87_RS00155 (A6J87_00155) vicK 27286..28626 (-) 1341 WP_080611394.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A6J87_RS00160 (A6J87_00160) vicR 28619..29326 (-) 708 WP_002884978.1 response regulator YycF Regulator
  A6J87_RS00165 (A6J87_00165) - 29612..30379 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  A6J87_RS00170 (A6J87_00170) - 30389..31222 (+) 834 WP_080611395.1 transporter substrate-binding domain-containing protein -
  A6J87_RS00175 (A6J87_00175) - 31240..31938 (+) 699 WP_080611396.1 amino acid ABC transporter permease -
  A6J87_RS00180 (A6J87_00180) - 31950..32600 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  A6J87_RS00185 (A6J87_00185) endA 32677..33558 (-) 882 WP_013990683.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50956.23 Da        Isoelectric Point: 5.1606

>NTDB_id=223215 A6J87_RS00155 WP_080611394.1 27286..28626(-) (vicK) [Streptococcus salivarius strain FDAARGOS_259]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYNELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=223215 A6J87_RS00155 WP_080611394.1 27286..28626(-) (vicK) [Streptococcus salivarius strain FDAARGOS_259]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTTTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTCAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTT
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTATATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACCTATAATGAATTGTTATCTAAGACTCCTGAGATT
CATTTGTCTCGTCGAGATGCCAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCTCTTATTCGTAAAGAATCTGGTTT
TATCTCAGGTCTGGTTGCCGTCCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGGGAACGTCGACTCTTTGTATCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCTTATCTGGAGGCACTTGATGATGGTGCTCTTGACGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAGCTTGACGTTGAAATGACTAATTTCACGGCCTTCATGACCTATATATTGAATC
GTTTCGATCAGATTAAGAGTCAAGAAACTAATACAGGTAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCGATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCGTTAATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment