Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   A6J72_RS00410 Genome accession   NZ_CP020433
Coordinates   74633..75337 (+) Length   234 a.a.
NCBI ID   WP_082311473.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 69633..80337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS00385 (A6J72_00390) - 69982..71199 (+) 1218 WP_318655700.1 multidrug efflux MFS transporter -
  A6J72_RS00390 (A6J72_00395) rpmG 71183..71332 (+) 150 WP_003034401.1 50S ribosomal protein L33 -
  A6J72_RS00395 (A6J72_00400) secG 71372..71605 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  A6J72_RS00400 (A6J72_00405) rnr 71696..74035 (+) 2340 WP_082311472.1 ribonuclease R -
  A6J72_RS00405 (A6J72_00410) smpB 73998..74465 (+) 468 WP_020998589.1 SsrA-binding protein SmpB -
  A6J72_RS00410 (A6J72_00415) comEA/celA/cilE 74633..75337 (+) 705 WP_082311473.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6J72_RS00415 (A6J72_00420) comEC/celB 75321..77555 (+) 2235 WP_082311474.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A6J72_RS00420 (A6J72_00425) - 77633..78346 (+) 714 WP_082311475.1 DUF805 domain-containing protein -
  A6J72_RS00425 (A6J72_00430) - 78786..79772 (+) 987 WP_082311476.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25329.77 Da        Isoelectric Point: 9.6236

>NTDB_id=222971 A6J72_RS00410 WP_082311473.1 74633..75337(+) (comEA/celA/cilE) [Streptococcus intermedius strain FDAARGOS_233]
MLEVIITKIKEYKILVGLSLIGLIIAGFFLMTSKSARQSNVGDIAQEATNAKLERKETSTETKKKQQKEETKSQKNLASA
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVATMGENVTNAASNNGQTLTT
DTDGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDELKNISGVGVKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=222971 A6J72_RS00410 WP_082311473.1 74633..75337(+) (comEA/celA/cilE) [Streptococcus intermedius strain FDAARGOS_233]
ATGTTAGAGGTAATCATCACAAAAATAAAAGAGTATAAAATTTTAGTTGGTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTCTGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGGCCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAAAATCTCAAAAGAATTTAGCGAGTGCA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT
AAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAACTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA
GATACCGATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCTAATTTGTCTGATTTACAGTCTATTTC
TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGAGCTTA
AAAATATATCAGGAGTTGGTGTTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus mitis SK321

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus pneumoniae D39

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus pneumoniae R6

50.644

99.573

0.504
  comEA Streptococcus thermophilus LMD-9

40.664

100

0.419
  comEA Lactococcus lactis subsp. cremoris KW2

36.481

99.573

0.363

Multiple sequence alignment