Detailed information NTG0222972

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A6J72_RS00415
• Genome accession: NZ_CP020433
• Coordinates: 75321..77555 (+)
• Length: 744 a.a.
• NCBI ID: WP_082311474.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_233
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 70321..82555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J72_RS00390 (A6J72_00395)	rpmG	71183..71332 (+)	150	WP_003034401.1	50S ribosomal protein L33	-
A6J72_RS00395 (A6J72_00400)	secG	71372..71605 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
A6J72_RS00400 (A6J72_00405)	rnr	71696..74035 (+)	2340	WP_082311472.1	ribonuclease R	-
A6J72_RS00405 (A6J72_00410)	smpB	73998..74465 (+)	468	WP_020998589.1	SsrA-binding protein SmpB	-
A6J72_RS00410 (A6J72_00415)	comEA/celA/cilE	74633..75337 (+)	705	WP_082311473.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6J72_RS00415 (A6J72_00420)	comEC/celB	75321..77555 (+)	2235	WP_082311474.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6J72_RS00420 (A6J72_00425)	-	77633..78346 (+)	714	WP_082311475.1	DUF805 domain-containing protein	-
A6J72_RS00425 (A6J72_00430)	-	78786..79772 (+)	987	WP_082311476.1	Gfo/Idh/MocA family protein	-
A6J72_RS00430 (A6J72_00435)	-	79797..80450 (+)	654	WP_021002684.1	uracil-DNA glycosylase	-
A6J72_RS00435 (A6J72_00440)	-	80477..80947 (+)	471	WP_003072602.1	8-oxo-dGTP diphosphatase	-
A6J72_RS00440 (A6J72_00445)	-	80959..82233 (+)	1275	WP_003072603.1	dihydroorotase	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85337.31 Da
• Isoelectric Point: 10.1265

>NTDB_id=222972 A6J72_RS00415 WP_082311474.1 75321..77555(+) (comEC/celB) [Streptococcus intermedius strain FDAARGOS_233]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSNWLAGVGLIFLLIRLSRIYSLKEWFTTFMILACFAVFFLVRRELADRKIKV
EAPPVRQVAVLPDTIKVNGDSLSFRGKAKGQTYQIYYKLKSKKEKLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSFQPFERLSSWRRKALVFIKRNFPNPMSNYMTGLLFGALDTDFGEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKSLLRLGLTQEIVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLI
MPSFLLTAGGVLSCAYAFIISVLDFKGLTPYKKIIIESIVISLGILPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
IIFLVSPFIKLTQVNFLFECLESSIRWLASMFSRPVVLGKPNPLLLIAMLLVLAILYDIRQNKKWLIFLSLFLSLLFFVA
KFPLQNEITMIDVGKGDSIFMRDWRGSTVLIDVGGREEIRKKESWQERISSSNAERTLIPYLKSRGVDTIDTLVLTNPNS
DYAGDVLEVAKKFSIKKIFIPRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGSQNSSSSKFLQQVRPVIALISTGENNSSKSLSQETIERFDWLNTKIY
RTDKQGAIKFSGWTTWQLETVQQP

Nucleotide

• Length: 2235 bp

>NTDB_id=222972 A6J72_RS00415 WP_082311474.1 75321..77555(+) (comEC/celB) [Streptococcus intermedius strain FDAARGOS_233]
ATGTCACAGTGGATTAAGATATTTCCGATCAAACCAATTTACATTGCTTTCTTACTTGTCTGGTTATATTTTGCAATCTA
TCAAAGTAATTGGTTGGCAGGAGTGGGATTGATCTTTCTGTTAATTCGTCTTTCTCGCATATATTCGCTAAAAGAATGGT
TTACAACTTTCATGATTCTCGCTTGTTTTGCTGTTTTTTTCCTTGTTCGTAGGGAACTGGCGGATCGGAAGATAAAAGTA
GAAGCTCCTCCTGTAAGACAAGTTGCGGTTTTACCTGATACAATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCAAAAGGACAGACATATCAAATTTACTACAAATTGAAATCAAAAAAAGAAAAGTTGGCTTTTCAAAATCTATCCAGCC
TTGTTACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGCCAAGATAGGGTTAGCTTCCAACCGTT
TGAGCGGCTGTCTAGCTGGCGAAGAAAAGCATTGGTTTTCATTAAGAGAAATTTCCCGAATCCAATGAGCAATTATATGA
CAGGGCTTTTGTTCGGAGCTTTGGATACAGATTTTGGTGAAATGAATAACCTTTATTCGAGCTTGGGAATTATTCATTTA
TTTGCATTGTCTGGTATGCAAGTTGGTTTTTTTATGGAAGGGTTTCGTAAGTCACTGTTGAGATTGGGGCTTACGCAGGA
AATAGTTCATAAGTGTCAATATCCATTTTCTTTTTTTTATGCTGGAATGACAGGTTTTTCAGTATCCGTTGTACGGAGTT
TAATCCAGAAATTATTGTCACAACACGGCATTACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGATT
ATGCCCTCCTTTCTTTTAACAGCAGGAGGAGTACTTTCTTGTGCGTATGCTTTTATCATTAGCGTTTTAGATTTTAAAGG
CCTGACTCCTTATAAAAAGATTATTATAGAGAGTATTGTCATTTCGCTTGGCATTTTACCAATTTTAATCTTTTATTTCG
GAGAATTTCAGCCCTGGTCTATTTTATTGACATTTGTTTTTTCGTTGATTTTCGATATAGTGATGTTACCGGGGCTAACG
ATAATTTTTCTTGTTTCCCCTTTCATAAAACTCACTCAAGTTAATTTTCTATTTGAATGCTTAGAAAGTAGCATTCGCTG
GTTAGCAAGTATGTTTAGCAGACCAGTCGTTCTTGGCAAACCTAATCCACTTTTGCTAATCGCTATGTTGCTTGTATTAG
CTATCTTGTATGATATTCGGCAAAATAAAAAATGGCTGATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTTGTAGCT
AAATTTCCTTTACAAAATGAAATCACAATGATTGATGTCGGGAAGGGAGATAGTATTTTTATGCGAGACTGGAGAGGGAG
CACTGTATTGATTGATGTTGGCGGACGTGAAGAAATTAGAAAAAAAGAAAGTTGGCAAGAACGTATAAGTAGTTCAAACG
CAGAGAGAACGCTGATTCCATATCTTAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCAAATTCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAGTTTTCGATAAAGAAAATTTTTATTCCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGGGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAACTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGATCCCAAAATTCATCAAGTTCTAAGTTCTTACAGCAAGTAAGACCAGTGATTGCCCTCATCT
CTACTGGGGAAAACAATTCATCCAAATCGTTAAGTCAAGAAACAATTGAGCGATTCGATTGGTTAAATACAAAGATCTAT
CGAACAGATAAACAGGGAGCTATTAAGTTTTCGGGTTGGACAACATGGCAATTAGAAACTGTTCAGCAACCATAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-175)

• Competence protein (Competence) (216-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.422	100	0.556
comEC/celB	Streptococcus mitis NCTC 12261	55.228	100	0.554
comEC/celB	Streptococcus pneumoniae TIGR4	54.217	100	0.544
comEC/celB	Streptococcus pneumoniae Rx1	53.681	100	0.539
comEC/celB	Streptococcus pneumoniae D39	53.681	100	0.539
comEC/celB	Streptococcus pneumoniae R6	53.681	100	0.539
comEC	Lactococcus lactis subsp. cremoris KW2	46.03	99.866	0.46