Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AZI10_RS08385 Genome accession   NZ_CP019750
Coordinates   1663689..1664939 (-) Length   416 a.a.
NCBI ID   WP_039105136.1    Uniprot ID   A0A0C1PXC1
Organism   Levilactobacillus brevis strain TMW 1.2113     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1658689..1669939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZI10_RS08370 (AZI10_08370) rny 1658894..1660453 (-) 1560 WP_085763328.1 ribonuclease Y -
  AZI10_RS13420 - 1660781..1660933 (+) 153 WP_021742880.1 hypothetical protein -
  AZI10_RS08375 (AZI10_08375) - 1661150..1662412 (+) 1263 WP_085762598.1 ISL3 family transposase -
  AZI10_RS08380 (AZI10_08380) recA 1662462..1663595 (-) 1134 WP_011667973.1 recombinase RecA Machinery gene
  AZI10_RS08385 (AZI10_08385) cinA 1663689..1664939 (-) 1251 WP_039105136.1 competence/damage-inducible protein A Machinery gene
  AZI10_RS08390 (AZI10_08390) pgsA 1664995..1665582 (-) 588 WP_043023203.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AZI10_RS08395 (AZI10_08395) - 1665644..1666549 (-) 906 WP_011668110.1 helix-turn-helix domain-containing protein -
  AZI10_RS08400 (AZI10_08400) yfmH 1666663..1667952 (-) 1290 WP_085763329.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  AZI10_RS08405 (AZI10_08405) yfmF 1667930..1669225 (-) 1296 WP_085763330.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44787.89 Da        Isoelectric Point: 5.4819

>NTDB_id=218243 AZI10_RS08385 WP_039105136.1 1663689..1664939(-) (cinA) [Levilactobacillus brevis strain TMW 1.2113]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDHDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=218243 AZI10_RS08385 WP_039105136.1 1663689..1664939(-) (cinA) [Levilactobacillus brevis strain TMW 1.2113]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGTGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACGAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAGCCCTTAGCAAATCGGACTGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTCATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCATGATGGTGTGGTTAGTGCGGCGACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGTTGGA
TACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGGCAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(259-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0C1PXC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.231

100

0.442

Multiple sequence alignment