Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   BZG42_RS00380 Genome accession   NZ_CP019557
Coordinates   57867..59237 (+) Length   456 a.a.
NCBI ID   WP_328706654.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 52867..64237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS00350 - 52989..53141 (+) 153 WP_155962529.1 hypothetical protein -
  BZG42_RS00355 (BZG42_00330) - 53745..53939 (+) 195 WP_155996076.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  BZG42_RS00360 (BZG42_00335) - 54149..54343 (+) 195 WP_024533168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  BZG42_RS00365 (BZG42_00340) - 54549..54704 (+) 156 WP_155969338.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  BZG42_RS00370 - 55216..55362 (+) 147 WP_155996237.1 hypothetical protein -
  BZG42_RS00375 (BZG42_00350) comA 55708..57861 (+) 2154 WP_155996236.1 peptide cleavage/export ABC transporter ComA Regulator
  BZG42_RS00380 (BZG42_00355) comB 57867..59237 (+) 1371 WP_328706654.1 bacteriocin secretion accessory protein Regulator
  BZG42_RS00385 (BZG42_00360) ruvB 59667..60665 (+) 999 WP_155996235.1 Holliday junction branch migration DNA helicase RuvB -
  BZG42_RS00390 (BZG42_00365) - 60836..61459 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  BZG42_RS00395 (BZG42_00370) comR 61562..62461 (+) 900 WP_155996234.1 helix-turn-helix domain-containing protein Regulator
  BZG42_RS00400 (BZG42_00375) - 62677..63906 (+) 1230 WP_155996233.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50517.15 Da        Isoelectric Point: 5.9213

>NTDB_id=216190 BZG42_RS00380 WP_328706654.1 57867..59237(+) (comB) [Streptococcus sp. DAT741]
MMEHQLLESGEFYHRRYHNAASRVILPSFALLVFLMMFAFFAKKELTVVTRATVEPLHVLSKIQSTSNNPIKMNYLKENQ
EVAVGDVLVEYQSSSEQIQEEGIKKKITLLKEQLSQLELLKKSLESGENQFPQEDKHGYSQTFVDYRNKLLTLESNVEQQ
NTTIAAQNAATSQLQTELGNIVKTSQKALSDYKNLRMAIQSDAEISEDNAGYSLYVGYTTQLSQAAGIAEKTTLKQQMLT
QVDNQISQLENQLATYRVQYAGAGAQQAYATNLDSQSASLKSQYLTKVAQEWTSLTSQLGELEGTLGLQENMRAKTKIVA
NQAGIIHLNSEVEGASMIAEGTIIAHIYPSLAEIKKVKVTAYVSSKDVASLSEGDVIHFSAQASQAGQIRLTSTITSIAT
SATKTEAGNFFKIEAEADLSKAFAEKIRYGLEGKFVVITGEKTYFQYIVDEFLGKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=216190 BZG42_RS00380 WP_328706654.1 57867..59237(+) (comB) [Streptococcus sp. DAT741]
ATGATGGAACATCAGCTATTAGAGAGTGGGGAATTTTACCATCGGCGTTATCATAATGCGGCAAGTAGAGTCATATTGCC
AAGTTTTGCTTTATTAGTCTTTTTGATGATGTTTGCCTTCTTTGCTAAGAAAGAACTGACGGTAGTGACTCGAGCAACTG
TTGAGCCACTTCATGTTTTATCCAAAATTCAATCCACAAGCAACAATCCTATTAAGATGAATTATTTGAAAGAAAATCAG
GAAGTTGCTGTGGGTGATGTTTTGGTTGAATATCAGTCTTCCAGTGAGCAGATTCAAGAAGAAGGTATTAAGAAAAAAAT
TACTCTGTTAAAGGAGCAATTATCTCAGCTTGAACTGTTGAAAAAGAGTTTAGAATCGGGAGAAAACCAGTTTCCTCAAG
AGGATAAGCATGGTTATTCACAAACCTTTGTTGATTATCGAAATAAATTATTGACATTGGAGAGCAATGTAGAGCAGCAG
AATACCACGATTGCTGCTCAGAATGCAGCTACCAGTCAATTGCAGACGGAATTAGGTAATATAGTCAAAACCAGTCAAAA
GGCATTGTCAGATTATAAGAATCTCAGAATGGCCATTCAATCTGACGCTGAAATTTCTGAGGATAATGCAGGTTATTCAC
TCTATGTGGGATATACAACTCAATTATCTCAAGCAGCTGGTATAGCTGAAAAAACAACTCTTAAACAGCAGATGTTAACG
CAGGTAGATAACCAGATTAGTCAATTAGAAAATCAGTTGGCTACTTATCGGGTACAGTATGCTGGGGCGGGAGCTCAACA
AGCCTATGCCACTAATTTAGATAGTCAGTCTGCATCGCTCAAATCCCAATATTTGACCAAGGTTGCCCAAGAGTGGACTT
CTCTAACAAGTCAATTAGGTGAACTTGAAGGGACATTGGGGTTACAAGAAAATATGAGAGCTAAGACAAAGATTGTAGCC
AATCAAGCAGGGATTATTCATCTAAATAGTGAAGTTGAGGGAGCATCTATGATTGCAGAAGGTACGATCATTGCTCACAT
TTATCCGAGTTTGGCTGAGATTAAAAAGGTAAAAGTTACCGCCTATGTATCCTCGAAAGATGTTGCCAGCCTGTCTGAGG
GAGATGTGATTCATTTTTCTGCTCAAGCTAGTCAAGCAGGACAGATTCGCCTGACTTCTACCATCACTTCTATTGCAACC
AGTGCGACCAAGACAGAAGCAGGAAATTTCTTTAAGATTGAAGCGGAGGCAGACTTATCAAAAGCATTTGCTGAGAAAAT
ACGGTATGGATTAGAAGGGAAATTTGTGGTAATTACAGGAGAGAAGACTTATTTTCAGTATATTGTAGATGAATTTTTAG
GGAAAAAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(318-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

51.549

99.123

0.511
  comB Streptococcus pneumoniae Rx1

49.89

99.781

0.498
  comB Streptococcus pneumoniae D39

49.89

99.781

0.498
  comB Streptococcus pneumoniae R6

49.89

99.781

0.498
  comB Streptococcus pneumoniae TIGR4

49.67

99.781

0.496
  comB Streptococcus mitis SK321

49.67

99.781

0.496
  comB Streptococcus mitis NCTC 12261

49.231

99.781

0.491

Multiple sequence alignment