Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   BZG42_RS00395 Genome accession   NZ_CP019557
Coordinates   61562..62461 (+) Length   299 a.a.
NCBI ID   WP_155996234.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 56562..67461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS00380 (BZG42_00355) comB 57867..59237 (+) 1371 WP_328706654.1 bacteriocin secretion accessory protein Regulator
  BZG42_RS00385 (BZG42_00360) ruvB 59667..60665 (+) 999 WP_155996235.1 Holliday junction branch migration DNA helicase RuvB -
  BZG42_RS00390 (BZG42_00365) - 60836..61459 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  BZG42_RS00395 (BZG42_00370) comR 61562..62461 (+) 900 WP_155996234.1 helix-turn-helix domain-containing protein Regulator
  BZG42_RS00400 (BZG42_00375) - 62677..63906 (+) 1230 WP_155996233.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  BZG42_RS00410 (BZG42_00385) - 64108..65607 (+) 1500 WP_155996232.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35611.68 Da        Isoelectric Point: 4.4665

>NTDB_id=216191 BZG42_RS00395 WP_155996234.1 61562..62461(+) (comR) [Streptococcus sp. DAT741]
MDNKEFGQRVRQLREQAMITREQFCDDEMELSVRQLTRIEAGTCKPTFSKINFIADRLGMGLYELMPDYIKLPERYSKLK
FDVLRTPTYGNEGLVETRNEMIAEIYDEYYDDLPEEEQIAMDAFQSIIDVFETKSTQYGREILDDYFEQVYRKEKYTIND
LLILRLYLEHIRFEETSSQMFQIFLDMVKHFPNQTEAIDPGDLFIFRDIMLTSIGILGTKEQFGYIPVLFDTLDKLMMST
QDFQKKPILNLLKWKYELRIHGNKERAREFYEEAVLFAKMIASPHLAEKLEEEWANDSQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=216191 BZG42_RS00395 WP_155996234.1 61562..62461(+) (comR) [Streptococcus sp. DAT741]
ATGGATAATAAGGAATTTGGTCAGCGTGTACGGCAACTACGAGAACAAGCAATGATAACACGAGAACAGTTTTGTGATGA
TGAAATGGAACTCTCTGTTCGTCAGTTAACTCGGATTGAGGCTGGTACCTGTAAGCCAACATTTTCTAAGATAAATTTTA
TCGCTGATCGTTTGGGGATGGGTCTATATGAACTAATGCCAGATTACATCAAACTACCAGAGAGATATTCAAAATTGAAA
TTTGATGTTCTGCGAACGCCTACATATGGGAATGAGGGATTGGTAGAAACACGCAATGAAATGATTGCGGAGATTTATGA
CGAATACTATGATGATCTGCCAGAAGAAGAACAAATAGCAATGGATGCTTTTCAATCCATTATTGACGTGTTTGAAACTA
AATCTACTCAATATGGTCGTGAAATATTGGATGACTATTTTGAACAAGTATATAGAAAAGAAAAATATACCATCAACGAT
TTATTGATTCTTAGGCTATACCTTGAGCACATAAGGTTCGAGGAAACCTCATCGCAAATGTTTCAGATTTTTTTGGATAT
GGTTAAGCATTTTCCAAATCAAACGGAAGCTATAGATCCGGGTGATTTATTCATATTCCGAGATATTATGCTTACTTCAA
TAGGGATATTAGGAACAAAAGAGCAATTTGGCTATATCCCTGTGTTATTTGATACACTGGATAAACTGATGATGTCTACT
CAAGATTTCCAAAAGAAACCAATTTTGAATCTTCTTAAGTGGAAATATGAACTGCGTATTCATGGGAATAAAGAACGTGC
ACGTGAGTTTTATGAAGAAGCAGTTCTGTTTGCGAAAATGATTGCAAGTCCTCATTTGGCTGAAAAATTAGAGGAGGAGT
GGGCTAACGATAGTCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

60.87

100

0.609
  comR Streptococcus suis 05ZYH33

60.87

100

0.609
  comR Streptococcus suis D9

58.472

100

0.589
  comR Streptococcus mutans UA159

38.127

100

0.381
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.966

96.99

0.378
  comR Streptococcus pyogenes MGAS8232

36.949

98.662

0.365

Multiple sequence alignment