Detailed information NTG0216189

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: BZG42_RS00375
• Genome accession: NZ_CP019557
• Coordinates: 55708..57861 (+)
• Length: 717 a.a.
• NCBI ID: WP_155996236.1
• Uniprot ID: -
• Organism: Streptococcus sp. DAT741
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 50708..62861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZG42_RS00330	-	51792..51935 (+)	144	WP_155962526.1	hypothetical protein	-
BZG42_RS00335 (BZG42_00315)	-	51987..52175 (+)	189	WP_155996238.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00340 (BZG42_00320)	-	52385..52567 (+)	183	WP_024533150.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00345	-	52651..52824 (+)	174	WP_155996079.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00350	-	52989..53141 (+)	153	WP_155962529.1	hypothetical protein	-
BZG42_RS00355 (BZG42_00330)	-	53745..53939 (+)	195	WP_155996076.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00360 (BZG42_00335)	-	54149..54343 (+)	195	WP_024533168.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00365 (BZG42_00340)	-	54549..54704 (+)	156	WP_155969338.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
BZG42_RS00370	-	55216..55362 (+)	147	WP_155996237.1	hypothetical protein	-
BZG42_RS00375 (BZG42_00350)	comA	55708..57861 (+)	2154	WP_155996236.1	peptide cleavage/export ABC transporter ComA	Regulator
BZG42_RS00380 (BZG42_00355)	comB	57867..59237 (+)	1371	WP_328706654.1	bacteriocin secretion accessory protein	Regulator
BZG42_RS00385 (BZG42_00360)	ruvB	59667..60665 (+)	999	WP_155996235.1	Holliday junction branch migration DNA helicase RuvB	-
BZG42_RS00390 (BZG42_00365)	-	60836..61459 (+)	624	WP_155962542.1	HAD-IA family hydrolase	-
BZG42_RS00395 (BZG42_00370)	comR	61562..62461 (+)	900	WP_155996234.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80948.08 Da
• Isoelectric Point: 7.0769

>NTDB_id=216189 BZG42_RS00375 WP_155996236.1 55708..57861(+) (comA) [Streptococcus sp. DAT741]
MKFRKRHYRAQVDTRDCGVAALAMILEYHHSHHSLASLRELAKTTMEGTTAFGLVKVAEDLGLETRAIRADMSLFEVGDL
TYPFIAHVLKDGKLMHYYVVTGADEKTIHIADPDPSVKLTKLTRERFEQEWTGVSLFMAPRPEYQPHKEKKQGLLSFVPL
LAKQKRLIGNIILATLLVTLINIVGSYYLQSIIDTYVPNQMKTTLGVISIGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIILIISVVLFSQNIYLFFIALLSLPIYSV
IIFAFMKPFERMNQEVMETNAVLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVDYLKKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGATLVMDNKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTARVANNRLNEVYLVESEFADQKTVTDLSLV
SGDIDFRDVSYKYGYGADVLSDINLTIKRGEKISFVGVSGSGKTTLAKMIVNFYDPYKGEINLNNVNLNQIDKHALRQHI
NYLPQQPYIFNGTILENLLLGAKEGTTQEDVLRAVEIACIREDIEKMPLNYQTELTSDGSGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLALDKTLIFIVHRLTIAERTERVVVLDKGKIVEQGCHRELLDQQGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=216189 BZG42_RS00375 WP_155996236.1 55708..57861(+) (comA) [Streptococcus sp. DAT741]
ATGAAGTTTAGGAAACGGCATTATAGGGCTCAGGTGGATACACGAGATTGTGGTGTAGCCGCTCTTGCAATGATTTTGGA
GTACCATCATTCTCATCATTCTTTGGCAAGTCTTCGAGAACTGGCTAAAACAACCATGGAAGGAACGACAGCTTTTGGAC
TAGTTAAAGTAGCCGAAGACTTGGGGCTTGAAACTCGCGCAATTCGAGCAGATATGTCCTTATTTGAAGTGGGAGATTTA
ACTTATCCCTTCATAGCTCATGTACTGAAAGATGGCAAGCTCATGCACTACTACGTTGTTACGGGTGCGGATGAGAAGAC
CATCCATATTGCAGATCCCGATCCTTCGGTCAAGTTAACCAAGTTAACTCGTGAACGATTTGAACAGGAATGGACAGGGG
TATCCTTATTCATGGCTCCTAGACCGGAATATCAACCTCACAAAGAGAAGAAGCAAGGCTTGTTGTCTTTTGTTCCCTTG
CTGGCAAAGCAAAAGAGATTGATTGGCAATATTATTTTGGCTACTCTTTTGGTGACGCTCATCAATATTGTTGGATCTTA
TTATCTACAATCCATCATTGATACCTATGTTCCAAATCAGATGAAGACAACTTTGGGAGTTATCTCAATTGGTTTAGTTG
TGGTGTATGCCTTGCAACAGTTGTTGTCTTACGCACAAGAGTATCTGCTCATTATACTGGGGCAAAGACTATCTATAGAT
GTTATCCTATCTTATATCAGACATGTATTCCATTTGCCAATGTCTTTTTTTGCAACACGGCGCACAGGGGAAATCGTTTC
TCGCTTTACAGATGCAAACTCTATTATTGATGCTTTGGCAAGTACAATTCTATCTATTTTCTTAGATGTATCCATTATTT
TGATTATTTCGGTTGTCTTATTTAGTCAGAATATTTACTTGTTTTTTATAGCTTTGTTGTCATTGCCGATTTATTCTGTC
ATTATTTTTGCATTTATGAAGCCATTTGAACGCATGAATCAGGAAGTAATGGAAACAAATGCTGTTTTGTCTTCTTCTAT
TATCGAAGACATCAATGGCATTGAAACAATTAAATCATTGACCAGTGAAAAACAACGTTATCAGAAAATTGATAAAGAAT
TTGTAGACTATCTGAAAAAATCTTTTGCCTATAACAAGGCAGAAGGACAACAAAAAGTGTTAAAGCGCTTGGCTCAGCTA
GTGCTGAACGTGGCTATTTTGTGGTTGGGAGCAACTCTCGTCATGGACAATAAGATGACGCTCGGTCAGCTCATCACGTT
CAATACCTTATTGGTCTACTTCACTAATCCTCTGGAAAATATTATCAATCTACAAACAAAACTTCAAACAGCTCGTGTAG
CAAATAATCGTCTCAATGAAGTTTATTTAGTTGAATCTGAGTTTGCGGATCAAAAGACAGTCACTGACTTGTCCCTGGTT
TCAGGAGATATTGATTTTAGAGATGTTAGTTATAAATATGGGTATGGTGCAGATGTCTTGTCAGACATCAATTTGACAAT
CAAGCGTGGTGAGAAGATTTCTTTTGTCGGAGTTTCTGGATCAGGTAAAACAACGCTGGCCAAGATGATAGTAAATTTTT
ATGATCCTTATAAGGGGGAGATTAACTTGAACAACGTAAATCTCAACCAAATTGACAAGCATGCTTTGCGTCAGCACATC
AATTACTTACCACAACAACCCTATATCTTTAATGGAACTATTTTAGAGAATCTCTTGCTAGGTGCCAAAGAGGGGACCAC
TCAGGAGGATGTCTTGCGAGCAGTAGAAATTGCCTGCATCAGAGAAGACATTGAAAAAATGCCTCTGAATTATCAGACGG
AGCTGACATCGGATGGATCAGGTATATCGGGTGGTCAACGCCAGCGCATCGCTCTGGCTCGAGCGTTGTTGACAGATGCT
CCGATTATGATTTTGGATGAGGCTACCAGTAGTTTAGACATCCTGACGGAGAAGCGAATTGTTGATAATTTGCTCGCCTT
GGATAAGACATTGATTTTTATTGTTCATCGTCTAACCATTGCGGAACGAACAGAGCGTGTCGTTGTACTTGATAAGGGAA
AAATTGTGGAACAAGGTTGTCATAGAGAACTACTCGATCAACAGGGATTTTATGCACATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	81.032	100	0.81
comA	Streptococcus pneumoniae Rx1	80.893	100	0.809
comA	Streptococcus pneumoniae D39	80.893	100	0.809
comA	Streptococcus pneumoniae R6	80.893	100	0.809
comA	Streptococcus mitis SK321	80.753	100	0.808
comA	Streptococcus pneumoniae TIGR4	80.614	100	0.806
comA	Streptococcus gordonii str. Challis substr. CH1	77.964	100	0.78
comA/nlmT	Streptococcus mutans UA159	64.017	100	0.64