Detailed information NTG0214684

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: BWQ98_RS04830
• Genome accession: NZ_CP019299
• Coordinates: 905103..905753 (+)
• Length: 216 a.a.
• NCBI ID: WP_050210310.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HKU1-14
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 900103..910753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWQ98_RS04790 (BWQ98_04795)	-	900599..900814 (+)	216	WP_001232081.1	YozE family protein	-
BWQ98_RS04795 (BWQ98_04800)	-	900900..901868 (+)	969	WP_000658183.1	PhoH family protein	-
BWQ98_RS04800 (BWQ98_04805)	-	902048..902548 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
BWQ98_RS04805 (BWQ98_04810)	-	902551..902877 (+)	327	Protein_910	TfoX/Sxy family protein	-
BWQ98_RS11490	ald	903178..904289 (-)	1112	Protein_911	alanine dehydrogenase	-
BWQ98_RS04825 (BWQ98_04830)	-	904466..905035 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
BWQ98_RS04830 (BWQ98_04835)	comEA/celA/cilE	905103..905753 (+)	651	WP_050210310.1	helix-hairpin-helix domain-containing protein	Machinery gene
BWQ98_RS04835 (BWQ98_04840)	comEC/celB	905737..907977 (+)	2241	WP_127245045.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BWQ98_RS04840 (BWQ98_04845)	-	908156..908344 (+)	189	WP_050210312.1	hypothetical protein	-
BWQ98_RS04845 (BWQ98_04850)	-	908376..908963 (+)	588	WP_050210313.1	ABC transporter ATP-binding protein	-
BWQ98_RS04850 (BWQ98_04855)	-	908967..910148 (+)	1182	WP_000655935.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23251.61 Da
• Isoelectric Point: 5.5171

>NTDB_id=214684 BWQ98_RS04830 WP_050210310.1 905103..905753(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain HKU1-14]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLLVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGTKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=214684 BWQ98_RS04830 WP_050210310.1 905103..905753(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain HKU1-14]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCTTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAGCTTAAACAGGTTAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATAGACCATCGTGAGGCAAATGG
GAAATTCAAGTCGATTGATGAACTCAAGAAGGTCTCTGGCATTGGTACTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae D39	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae R6	97.222	100	0.972
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	44.053	100	0.463
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37
comEA	Bacillus subtilis subsp. subtilis str. 168	42.105	87.963	0.37