Detailed information NTG0214685

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BWQ98_RS04835
• Genome accession: NZ_CP019299
• Coordinates: 905737..907977 (+)
• Length: 746 a.a.
• NCBI ID: WP_127245045.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HKU1-14
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 900737..912977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWQ98_RS04795 (BWQ98_04800)	-	900900..901868 (+)	969	WP_000658183.1	PhoH family protein	-
BWQ98_RS04800 (BWQ98_04805)	-	902048..902548 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
BWQ98_RS04805 (BWQ98_04810)	-	902551..902877 (+)	327	Protein_910	TfoX/Sxy family protein	-
BWQ98_RS11490	ald	903178..904289 (-)	1112	Protein_911	alanine dehydrogenase	-
BWQ98_RS04825 (BWQ98_04830)	-	904466..905035 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
BWQ98_RS04830 (BWQ98_04835)	comEA/celA/cilE	905103..905753 (+)	651	WP_050210310.1	helix-hairpin-helix domain-containing protein	Machinery gene
BWQ98_RS04835 (BWQ98_04840)	comEC/celB	905737..907977 (+)	2241	WP_127245045.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BWQ98_RS04840 (BWQ98_04845)	-	908156..908344 (+)	189	WP_050210312.1	hypothetical protein	-
BWQ98_RS04845 (BWQ98_04850)	-	908376..908963 (+)	588	WP_050210313.1	ABC transporter ATP-binding protein	-
BWQ98_RS04850 (BWQ98_04855)	-	908967..910148 (+)	1182	WP_000655935.1	membrane protein	-
BWQ98_RS04855 (BWQ98_04860)	infC	910455..910985 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
BWQ98_RS04860 (BWQ98_04865)	rpmI	911018..911218 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
BWQ98_RS04865 (BWQ98_04870)	rplT	911270..911629 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
BWQ98_RS04870 (BWQ98_04875)	-	911687..912067 (+)	381	WP_050219036.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84624.17 Da
• Isoelectric Point: 9.2732

>NTDB_id=214685 BWQ98_RS04835 WP_127245045.1 905737..907977(+) (comEC/celB) [Streptococcus pneumoniae strain HKU1-14]
MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCLFFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGMIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLWDITGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKQYPYLEVDVLKAAQHGSKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=214685 BWQ98_RS04835 WP_127245045.1 905737..907977(+) (comEC/celB) [Streptococcus pneumoniae strain HKU1-14]
ATGTTACAGTGGATTAAGAACATCCCCATTCCCCTAATTTACCTGAGTTTTTTGTTACTTTGGTTTTATTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCATGGAAATCAGCAG
GCAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGCCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTCTGCCTGACACTGTTAAGGTCAATGGTGATAGTCTGTCCTTTCGCGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTTTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTAACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGAATGATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTATGGGATATAACTGGGAAAAC
CATTCTCATAGATGTCGGTGGCAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCAATATCCTTACTTAGA
GGTGGATGTATTGAAAGCTGCCCAACATGGCTCTAAAAAGTCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-697)

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae D39	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae R6	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae TIGR4	95.442	100	0.954
comEC/celB	Streptococcus mitis SK321	92.225	100	0.922
comEC/celB	Streptococcus mitis NCTC 12261	91.544	99.866	0.914
comEC	Lactococcus lactis subsp. cremoris KW2	44.355	99.732	0.442