Detailed information NTG0210798

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: BUM80_RS00180
• Genome accession: NZ_CP018838
• Coordinates: 34261..35937 (-)
• Length: 558 a.a.
• NCBI ID: WP_196299874.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11A
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 29261..40937

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS00150 (BUM80_00145)	-	29595..29924 (-)	330	WP_000132572.1	hypothetical protein	-
BUM80_RS00155 (BUM80_00150)	-	30201..30539 (+)	339	WP_000682135.1	LytTR family DNA-binding domain-containing protein	-
BUM80_RS00160 (BUM80_00155)	comE/blpR	30544..31281 (+)	738	WP_001219120.1	LytTR family DNA-binding domain-containing protein	Regulator
BUM80_RS00165 (BUM80_00160)	-	31295..32635 (+)	1341	WP_001017638.1	sensor histidine kinase	-
BUM80_RS00170 (BUM80_00165)	blpC	32677..32832 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
BUM80_RS00175 (BUM80_00170)	-	32889..34250 (-)	1362	WP_001069091.1	bacteriocin secretion accessory protein	-
BUM80_RS00180 (BUM80_00175)	comA/nlmT	34261..35937 (-)	1677	WP_196299874.1	peptide cleavage/export ABC transporter	Regulator
BUM80_RS12070 (BUM80_00180)	comA/nlmT	35831..36418 (-)	588	WP_001810228.1	cysteine peptidase family C39 domain-containing protein	Regulator
BUM80_RS00185 (BUM80_00185)	blpI	36700..36897 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
BUM80_RS00195 (BUM80_00195)	blpJ	37364..37633 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
BUM80_RS00200 (BUM80_00200)	blpU	37702..37932 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
BUM80_RS00205 (BUM80_00205)	-	37935..38054 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
BUM80_RS00210 (BUM80_00210)	-	38351..38515 (+)	165	WP_000727118.1	hypothetical protein	-
BUM80_RS00215 (BUM80_00215)	-	38512..38916 (+)	405	WP_000846944.1	hypothetical protein	-
BUM80_RS00220	-	39114..39918 (+)	805	Protein_39	IS5 family transposase	-
BUM80_RS00225 (BUM80_00230)	blpM	40068..40322 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
BUM80_RS00230 (BUM80_00235)	blpN	40338..40541 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
BUM80_RS00240 (BUM80_00245)	cipB	40785..40934 (+)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator

Sequence

Protein

• Length: 558 a.a.
• Molecular weight: 62923.20 Da
• Isoelectric Point: 6.7844

>NTDB_id=210798 BUM80_RS00180 WP_196299874.1 34261..35937(-) (comA/nlmT) [Streptococcus pneumoniae strain 11A]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1677 bp

>NTDB_id=210798 BUM80_RS00180 WP_196299874.1 34261..35937(-) (comA/nlmT) [Streptococcus pneumoniae strain 11A]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (341-490)

• ABC transporter transmembrane region (ABC_membrane) (10-279)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.89	99.821	0.728
comA	Streptococcus mitis NCTC 12261	67.204	100	0.672
comA	Streptococcus pneumoniae D39	66.846	100	0.668
comA	Streptococcus pneumoniae R6	66.846	100	0.668
comA	Streptococcus pneumoniae Rx1	66.846	100	0.668
comA	Streptococcus mitis SK321	66.667	100	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.547	100	0.667
comA	Streptococcus pneumoniae TIGR4	66.487	100	0.665