Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BTR42_RS12050 Genome accession   NZ_CP018822
Coordinates   2417301..2418560 (-) Length   419 a.a.
NCBI ID   WP_077497920.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus DSM 16831     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2412301..2423560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTR42_RS12945 (BTR42_11765) - 2413852..2413980 (-) 129 WP_099046295.1 hypothetical protein -
  BTR42_RS12025 (BTR42_11770) - 2414072..2414389 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  BTR42_RS12030 (BTR42_11775) ruvX 2414422..2414841 (-) 420 WP_009855163.1 Holliday junction resolvase RuvX -
  BTR42_RS12035 (BTR42_11780) - 2414838..2415107 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  BTR42_RS12040 (BTR42_11785) spx 2415429..2415827 (-) 399 WP_009855164.1 transcriptional regulator Spx -
  BTR42_RS12045 (BTR42_11790) recA 2416097..2417251 (-) 1155 WP_009855165.1 recombinase RecA Machinery gene
  BTR42_RS12050 (BTR42_11795) cinA 2417301..2418560 (-) 1260 WP_077497920.1 competence/damage-inducible protein A Machinery gene
  BTR42_RS12055 (BTR42_11800) - 2418692..2419882 (-) 1191 WP_077497922.1 MFS transporter -
  BTR42_RS12730 (BTR42_11805) - 2420042..2420215 (-) 174 WP_167367618.1 hypothetical protein -
  BTR42_RS12060 (BTR42_11810) - 2420265..2420729 (-) 465 WP_077497924.1 hypothetical protein -
  BTR42_RS12065 (BTR42_11815) - 2420799..2421206 (-) 408 WP_077497926.1 hypothetical protein -
  BTR42_RS12070 - 2421369..2422210 (+) 842 Protein_2342 helix-turn-helix domain-containing protein -
  BTR42_RS12075 (BTR42_11830) ruvA 2422284..2422877 (-) 594 WP_009855172.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45453.81 Da        Isoelectric Point: 5.0671

>NTDB_id=210664 BTR42_RS12050 WP_077497920.1 2417301..2418560(-) (cinA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNDVTYVVLPGPPSELKPM
VLDSLVPLLSGNHKQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKADDVASAKAKLDALEHK
ILAKKTLNSIPLEQLLYGYGDDNSMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTNADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=210664 BTR42_RS12050 WP_077497920.1 2417301..2418560(-) (cinA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGATGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGACGTGACCTACGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGGAAACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGGCGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTACTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACTATTACAGCGGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTGGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAAATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACACCCAGCAGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.422

99.523

0.721
  cinA Streptococcus mitis SK321

71.053

99.761

0.709
  cinA Streptococcus mitis NCTC 12261

70.813

99.761

0.706
  cinA Streptococcus pneumoniae Rx1

69.856

99.761

0.697
  cinA Streptococcus pneumoniae TIGR4

69.856

99.761

0.697
  cinA Streptococcus pneumoniae R6

69.856

99.761

0.697
  cinA Streptococcus pneumoniae D39

69.617

99.761

0.695
  cinA Streptococcus suis isolate S10

53.606

99.284

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

45.972

100

0.463

Multiple sequence alignment