Detailed information NTG0210626

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: BTR42_RS03940
• Genome accession: NZ_CP018822
• Coordinates: 728751..729416 (+)
• Length: 221 a.a.
• NCBI ID: WP_077496500.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus DSM 16831
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 723751..734416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BTR42_RS03920 (BTR42_03585)	-	725170..726750 (+)	1581	WP_077496496.1	DEAD/DEAH box helicase	-
BTR42_RS03925 (BTR42_03590)	-	726794..727066 (-)	273	WP_009853764.1	GIY-YIG nuclease family protein	-
BTR42_RS03930 (BTR42_03595)	-	727041..727802 (-)	762	WP_077496498.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BTR42_RS03935 (BTR42_03600)	-	727910..728656 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
BTR42_RS03940 (BTR42_03605)	comEA	728751..729416 (+)	666	WP_077496500.1	helix-hairpin-helix domain-containing protein	Machinery gene
BTR42_RS03945 (BTR42_03610)	comEC/celB	729409..731640 (+)	2232	WP_077496502.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BTR42_RS03950 (BTR42_03615)	holA	731714..732751 (+)	1038	WP_077498002.1	DNA polymerase III subunit delta	-
BTR42_RS03955 (BTR42_03620)	sodA	732840..733448 (+)	609	WP_061458979.1	superoxide dismutase SodA	-
BTR42_RS03960 (BTR42_03625)	-	733600..734325 (+)	726	WP_077496504.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 23403.06 Da
• Isoelectric Point: 4.3235

>NTDB_id=210626 BTR42_RS03940 WP_077496500.1 728751..729416(+) (comEA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MIEEIKEKLLENKTLVAVLGTIIVMLIGFFAWSNVTKTTADAQSDLPALSTTFSASSSASDLKTERSSSQTETQKVFVDI
KGAVKNEGVYELSSGSRVTDVVKLAGGFTEDADKKSVNLAEKVTDEAVIYVARVGENVAPATTNSQANGSAQQEESSDKI
NLNTATLAELQTISGIGAKRAQDIIDYRDANGGFSSVDDLANVSGIGEKTLEKLKSEVTVD

Nucleotide

• Length: 666 bp

>NTDB_id=210626 BTR42_RS03940 WP_077496500.1 728751..729416(+) (comEA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGATTGAAGAAATAAAAGAAAAACTTTTGGAGAACAAAACGTTGGTAGCGGTGTTGGGAACAATAATTGTCATGTTAAT
CGGATTTTTTGCTTGGTCAAATGTGACAAAAACAACAGCGGATGCGCAAAGTGACCTACCTGCCCTAAGCACGACTTTTT
CGGCAAGTAGCAGCGCAAGTGATTTAAAAACAGAACGTTCAAGTTCGCAAACTGAAACTCAAAAAGTGTTTGTAGATATC
AAAGGCGCTGTGAAAAATGAGGGGGTTTATGAGCTTTCAAGTGGCAGTCGTGTGACAGATGTGGTCAAATTAGCAGGTGG
TTTTACAGAAGATGCTGATAAGAAGTCGGTGAATTTGGCTGAAAAAGTAACCGATGAAGCGGTGATTTATGTGGCAAGAG
TTGGTGAAAATGTTGCTCCTGCAACGACTAATTCACAAGCAAATGGCAGCGCTCAACAGGAAGAAAGTTCAGATAAAATC
AATCTTAATACCGCAACTTTGGCGGAACTCCAGACGATTTCTGGCATTGGCGCCAAACGTGCCCAAGACATTATTGACTA
CCGTGATGCCAATGGTGGTTTTTCATCAGTTGATGACTTGGCGAATGTGTCTGGTATCGGAGAAAAAACACTAGAAAAAC
TAAAATCTGAGGTGACCGTTGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (157-219)

• SLBB domain (SLBB) (78-131)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	48.069	100	0.507
comEA/celA/cilE	Streptococcus mitis SK321	47.059	100	0.471
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	45.74	100	0.462
comEA/celA/cilE	Streptococcus pneumoniae Rx1	44.843	100	0.452
comEA/celA/cilE	Streptococcus pneumoniae D39	44.843	100	0.452
comEA/celA/cilE	Streptococcus pneumoniae R6	44.843	100	0.452
comEA/celA/cilE	Streptococcus mitis NCTC 12261	44.395	100	0.448
comEA	Latilactobacillus sakei subsp. sakei 23K	37.668	100	0.38
comEA	Staphylococcus aureus MW2	36.036	100	0.362