Detailed information NTG0210627

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BTR42_RS03945
• Genome accession: NZ_CP018822
• Coordinates: 729409..731640 (+)
• Length: 743 a.a.
• NCBI ID: WP_077496502.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus DSM 16831
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 724409..736640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BTR42_RS03920 (BTR42_03585)	-	725170..726750 (+)	1581	WP_077496496.1	DEAD/DEAH box helicase	-
BTR42_RS03925 (BTR42_03590)	-	726794..727066 (-)	273	WP_009853764.1	GIY-YIG nuclease family protein	-
BTR42_RS03930 (BTR42_03595)	-	727041..727802 (-)	762	WP_077496498.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BTR42_RS03935 (BTR42_03600)	-	727910..728656 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
BTR42_RS03940 (BTR42_03605)	comEA	728751..729416 (+)	666	WP_077496500.1	helix-hairpin-helix domain-containing protein	Machinery gene
BTR42_RS03945 (BTR42_03610)	comEC/celB	729409..731640 (+)	2232	WP_077496502.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BTR42_RS03950 (BTR42_03615)	holA	731714..732751 (+)	1038	WP_077498002.1	DNA polymerase III subunit delta	-
BTR42_RS03955 (BTR42_03620)	sodA	732840..733448 (+)	609	WP_061458979.1	superoxide dismutase SodA	-
BTR42_RS03960 (BTR42_03625)	-	733600..734325 (+)	726	WP_077496504.1	YebC/PmpR family DNA-binding transcriptional regulator	-
BTR42_RS03965 (BTR42_03630)	queA	734357..735385 (-)	1029	WP_077496506.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
BTR42_RS03970 (BTR42_03635)	-	735561..736061 (+)	501	WP_012961668.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83738.04 Da
• Isoelectric Point: 8.5001

>NTDB_id=210627 BTR42_RS03945 WP_077496502.1 729409..731640(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MIKYFPIKPIQLAFLLTLLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLTCFAVFFLTKSNQTEQAYQAAPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTVVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVHKMTLWEKLHDVRRKAIVSIQQHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=210627 BTR42_RS03945 WP_077496502.1 729409..731640(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTACTCACTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GTTTGTGTTTAACCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCGCCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCTGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGGTTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACCTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTCATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCAACATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTGATTCGGAGTTTAATTCAGT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTAGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGTAAACCAAGTCTTGGTATCTTGGTGCTGCTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGTTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCACCAAGAAACGCTTGAACGCTTCCGAGCTCAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.83	99.865	0.528
comEC/celB	Streptococcus mitis SK321	52.291	99.865	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.279	100	0.513
comEC/celB	Streptococcus pneumoniae Rx1	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae D39	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae R6	50.74	100	0.507
comEC	Lactococcus lactis subsp. cremoris KW2	47.779	100	0.478