Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   IMCC3135_RS28770 Genome accession   NZ_CP018632
Coordinates   6652307..6653524 (+) Length   405 a.a.
NCBI ID   WP_088920721.1    Uniprot ID   A0A2Z2NXA8
Organism   Granulosicoccus antarcticus IMCC3135     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6647307..6658524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMCC3135_RS28750 (IMCC3135_29090) - 6648005..6649192 (+) 1188 WP_088920717.1 glycosyltransferase -
  IMCC3135_RS35320 (IMCC3135_29095) - 6649465..6649881 (+) 417 WP_088920718.1 pilin -
  IMCC3135_RS35325 (IMCC3135_29100) - 6649958..6650380 (+) 423 WP_088920719.1 pilin -
  IMCC3135_RS28765 (IMCC3135_29105) pilB 6650606..6652303 (+) 1698 WP_088920720.1 type IV-A pilus assembly ATPase PilB Machinery gene
  IMCC3135_RS28770 (IMCC3135_29110) pilC 6652307..6653524 (+) 1218 WP_088920721.1 type II secretion system F family protein Machinery gene
  IMCC3135_RS28775 (IMCC3135_29115) - 6653595..6654518 (+) 924 WP_088920722.1 prepilin peptidase -
  IMCC3135_RS28780 (IMCC3135_29120) coaE 6654565..6655173 (+) 609 WP_157736339.1 dephospho-CoA kinase -
  IMCC3135_RS28785 (IMCC3135_29125) mutT 6655166..6655567 (-) 402 WP_088920724.1 8-oxo-dGTP diphosphatase MutT -
  IMCC3135_RS28790 (IMCC3135_29130) argJ 6655571..6656803 (-) 1233 WP_088922137.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43885.30 Da        Isoelectric Point: 7.9375

>NTDB_id=209192 IMCC3135_RS28770 WP_088920721.1 6652307..6653524(+) (pilC) [Granulosicoccus antarcticus IMCC3135]
MAKSAAKAAIMFEWEGKSTSGHKQKGVISSPNADLVKAKLRRQGIIPSKIRKKRREFGGKQKIEASDIALFARQLTTMMG
AGVPMVQSFEIVANGLDNKSMRDMINGIKSEVESGSNLTNALRKYPDQFDELFCSLTEAGEQSGTLETLLGEIATYKEKS
ETLKKKIKKALFYPVAVLIIAFIVTAILLVFVVPQFEDLFVGMGGDLPAFTKMIVTASEFMQSWWYVLFGGAGAAVWFFA
QAKKRSKPFAEALDRLALKAPVFGDIVVKAATARFARTLATMSKAGVPLVEAMESVAGVAGNSVFEKAILTMKDEAATGQ
RLTTSIESSGLFSNMVVQMVAIGEESGSIDDMLAKVADYYEEEVDNAVDAMTSLMEPMIMAFLGVVIGGLVVGMYLPIFK
MGDAF

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=209192 IMCC3135_RS28770 WP_088920721.1 6652307..6653524(+) (pilC) [Granulosicoccus antarcticus IMCC3135]
ATGGCAAAGTCTGCAGCCAAAGCGGCCATCATGTTCGAATGGGAAGGTAAAAGCACCTCCGGACATAAACAGAAAGGTGT
AATTTCCAGCCCGAATGCCGACTTGGTCAAGGCCAAGCTGCGCCGACAAGGCATTATTCCTTCAAAGATCAGAAAGAAAC
GCCGAGAGTTCGGTGGCAAACAAAAAATCGAGGCCAGTGACATTGCGCTGTTCGCTCGCCAGCTGACGACCATGATGGGC
GCCGGTGTGCCCATGGTGCAGTCTTTCGAAATCGTTGCCAATGGCCTGGACAACAAGTCCATGCGCGATATGATCAACGG
TATCAAGTCAGAGGTTGAATCGGGCAGTAATCTGACCAACGCCTTGCGCAAATATCCGGATCAATTCGATGAATTGTTCT
GTAGCCTGACCGAAGCCGGTGAACAGTCAGGTACGCTGGAGACGCTGCTCGGCGAGATAGCCACGTACAAGGAAAAATCA
GAGACTCTGAAAAAGAAGATCAAGAAAGCACTGTTCTATCCGGTTGCCGTTTTGATCATTGCCTTTATCGTAACCGCCAT
CCTACTGGTATTCGTTGTACCACAGTTCGAGGATCTGTTCGTCGGCATGGGGGGAGATCTTCCGGCCTTTACCAAAATGA
TTGTTACCGCCTCAGAATTCATGCAGAGCTGGTGGTACGTTCTGTTCGGTGGCGCAGGTGCCGCGGTCTGGTTCTTTGCT
CAGGCAAAAAAGCGTTCCAAACCGTTTGCCGAAGCACTCGACAGGCTTGCACTCAAAGCCCCCGTCTTTGGCGACATTGT
CGTCAAGGCCGCCACTGCACGATTCGCCAGAACCCTGGCCACCATGTCGAAAGCGGGTGTACCTCTGGTTGAAGCCATGG
AATCTGTCGCAGGGGTTGCAGGTAACTCGGTATTCGAGAAAGCCATCCTCACCATGAAGGATGAGGCAGCGACCGGTCAA
CGCTTGACCACCTCGATCGAGAGTTCAGGTCTGTTCTCCAATATGGTGGTACAGATGGTCGCCATCGGTGAGGAGTCAGG
TTCTATCGATGACATGCTGGCCAAGGTGGCAGACTACTATGAAGAAGAAGTCGACAATGCAGTCGACGCCATGACCTCTC
TGATGGAACCCATGATCATGGCATTCCTGGGTGTTGTCATCGGTGGCCTGGTCGTCGGCATGTACCTGCCGATCTTCAAG
ATGGGTGATGCGTTCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z2NXA8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

55.309

100

0.553
  pilC Pseudomonas stutzeri DSM 10701

54.591

99.506

0.543
  pilC Acinetobacter baylyi ADP1

54.074

100

0.541
  pilC Legionella pneumophila strain ERS1305867

53.149

98.025

0.521
  pilG Neisseria meningitidis 44/76-A

42.356

98.519

0.417
  pilG Neisseria gonorrhoeae MS11

42.105

98.519

0.415
  pilC Vibrio cholerae strain A1552

38.52

96.79

0.373
  pilC Vibrio campbellii strain DS40M4

37.913

97.037

0.368

Multiple sequence alignment