Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SMA_0620 Genome accession   HE613569
Coordinates   621522..622187 (+) Length   221 a.a.
NCBI ID   CCF01911.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 616522..627187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0616 - 617942..619522 (+) 1581 CCF01907.1 Cold-shock DEAD-box protein A -
  SMA_0617 yhbQ 619565..619837 (-) 273 CCF01908.1 COG2827: putative endonuclease containing a URI domain -
  SMA_0618 yabB 619812..620573 (-) 762 CCF01909.1 COG4123: Predicted O-methyltransferase -
  SMA_0619 plsC 620681..621427 (+) 747 CCF01910.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SMA_0620 comEA 621522..622187 (+) 666 CCF01911.1 Late competence protein ComEA, DNA receptor Machinery gene
  SMA_0621 comEC/celB 622180..624411 (+) 2232 CCF01912.1 Late competence protein ComEC, DNA transport Machinery gene
  SMA_0622 yqenN 624459..625520 (+) 1062 CCF01913.1 DNA polymerase III delta subunit -
  SMA_0623 sodA 625609..626217 (+) 609 CCF01914.1 Manganese superoxide dismutase -
  SMA_0624 yebC 626368..627093 (+) 726 CCF01915.1 Hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23661.51 Da        Isoelectric Point: 4.4973

>NTDB_id=20345 SMA_0620 CCF01911.1 621522..622187(+) (comEA) [Streptococcus macedonicus ACA-DC 198]
MIEKIKEKLLENKTLVAMLGTILVMLIGFFAWSNVTKTTVDAQNDLPALSTTFSASSSASDLKTERSSSQTETQKVFVDI
KGAVKNEGVYELSNGRRVTDVVKLAGGFTEDADKKSVNLAEKVTDESMIYVARVGENVAPATTNSQVNGSAQQEESSDKI
NLNTATLAELQTISGIGAKRAQDIIDYRDANGGFSSVDDLANVSGIGEKTLEKLKSEVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=20345 SMA_0620 CCF01911.1 621522..622187(+) (comEA) [Streptococcus macedonicus ACA-DC 198]
ATGATTGAAAAAATAAAAGAAAAACTTTTAGAGAACAAAACGTTGGTAGCGATGTTGGGAACAATACTTGTCATGTTAAT
CGGATTTTTTGCTTGGTCAAACGTGACAAAAACAACAGTGGATGCACAAAATGACTTACCTGCCCTAAGCACGACTTTTT
CGGCAAGTAGCAGCGCAAGTGATTTAAAAACAGAACGTTCAAGTTCGCAAACTGAAACTCAAAAAGTGTTTGTAGATATC
AAAGGTGCTGTGAAAAATGAGGGTGTTTATGAGCTTTCAAACGGTAGGCGTGTGACAGATGTGGTTAAATTAGCAGGTGG
TTTTACAGAAGATGCTGATAAGAAGTCGGTGAATTTGGCTGAAAAAGTAACCGATGAATCAATGATTTATGTGGCAAGAG
TTGGTGAAAATGTTGCTCCTGCAACGACTAATTCACAAGTAAACGGTAGCGCTCAGCAGGAAGAAAGTTCAGATAAAATC
AATCTTAATACCGCAACTTTGGCAGAACTCCAGACGATTTCTGGCATTGGCGCCAAACGTGCCCAAGACATTATTGACTA
TCGTGATGCCAATGGTGGTTTTTCATCAGTTGATGACTTGGCGAATGTGTCTGGCATCGGAGAAAAAACACTAGAAAAGC
TAAAATCTGAGGTGACCGTTGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(78-131)

Helix-hairpin-helix motif (HHH_3)

(157-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

47.639

100

0.502
  comEA/celA/cilE Streptococcus mitis SK321

47.059

100

0.471
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.909

99.548

0.457
  comEA/celA/cilE Streptococcus mitis NCTC 12261

45.455

99.548

0.452
  comEA/celA/cilE Streptococcus pneumoniae Rx1

44.545

99.548

0.443
  comEA/celA/cilE Streptococcus pneumoniae D39

44.545

99.548

0.443
  comEA/celA/cilE Streptococcus pneumoniae R6

44.545

99.548

0.443
  comEA Latilactobacillus sakei subsp. sakei 23K

38.813

99.095

0.385

Multiple sequence alignment