Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SMA_0621 Genome accession   HE613569
Coordinates   622180..624411 (+) Length   743 a.a.
NCBI ID   CCF01912.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 617180..629411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0616 - 617942..619522 (+) 1581 CCF01907.1 Cold-shock DEAD-box protein A -
  SMA_0617 yhbQ 619565..619837 (-) 273 CCF01908.1 COG2827: putative endonuclease containing a URI domain -
  SMA_0618 yabB 619812..620573 (-) 762 CCF01909.1 COG4123: Predicted O-methyltransferase -
  SMA_0619 plsC 620681..621427 (+) 747 CCF01910.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SMA_0620 comEA 621522..622187 (+) 666 CCF01911.1 Late competence protein ComEA, DNA receptor Machinery gene
  SMA_0621 comEC/celB 622180..624411 (+) 2232 CCF01912.1 Late competence protein ComEC, DNA transport Machinery gene
  SMA_0622 yqenN 624459..625520 (+) 1062 CCF01913.1 DNA polymerase III delta subunit -
  SMA_0623 sodA 625609..626217 (+) 609 CCF01914.1 Manganese superoxide dismutase -
  SMA_0624 yebC 626368..627093 (+) 726 CCF01915.1 Hypothetical protein -
  SMA_0625 queA 627125..628153 (-) 1029 CCF01916.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  SMA_0626 - 628328..628828 (+) 501 Protein_625 Hypothetical protein -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 84044.59 Da        Isoelectric Point: 8.8509

>NTDB_id=20346 SMA_0621 CCF01912.1 622180..624411(+) (comEC/celB) [Streptococcus macedonicus ACA-DC 198]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLVLVFLWQQYGWKAWCQVCLCLSCFAVFFLTKSNQTEQAYQVVPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTIVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWDKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGTFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGYSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFMVMPN
FLLTTGGILSFTYAFILSFIDFNDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKNTKVILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVVLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKHVKIGKVLVSQGSLTKPDFVAKLQAMKTKVRVVTASDVLPIMGSYLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELVATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=20346 SMA_0621 CCF01912.1 622180..624411(+) (comEC/celB) [Streptococcus macedonicus ACA-DC 198]
TTGATTAAGTATTTTCCTATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGTCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GTTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGTAGTGCCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGAGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGATTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGATAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGTATGCAGGTCGGATTTTTTGTGGGGACATTCCGATTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
TATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTATTCTGTTTCGGTGATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTCATGGTTATGCCAAAT
TTTTTACTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTGACTTTAATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGTTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTTTTGGAAACTGTTATCAAGAACACTAAGGT
AATTTTGGGCGGTCCGATTGTTTTTGGGAAACCAAGTCTTGGTATCTTGGTGCTACTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGTTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACAGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGTGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGTAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAGGTGGCGAAACACGTAAAAATTGGTAAAGTGCTGGTGAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTAGTGATGTTTTGCCGATTATGGGAAGTTACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGGTTGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGGCATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTAA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAGACACTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(213-459)

Metallo-beta-lactamase superfamily (Lactamase_B)

(491-697)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

52.022

99.865

0.52
  comEC/celB Streptococcus mitis SK321

51.482

99.865

0.514
  comEC/celB Streptococcus pneumoniae TIGR4

50.471

100

0.505
  comEC/celB Streptococcus pneumoniae Rx1

49.933

100

0.499
  comEC/celB Streptococcus pneumoniae D39

49.933

100

0.499
  comEC/celB Streptococcus pneumoniae R6

49.933

100

0.499
  comEC Lactococcus lactis subsp. cremoris KW2

47.715

100

0.478

Multiple sequence alignment