Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   SPG_0308 Genome accession   CP001015
Coordinates   296481..298586 (+) Length   701 a.a.
NCBI ID   ACF55903.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 291481..303586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_0304 - 292317..292634 (+) 318 ACF55606.1 cell division protein FtsL -
  SPG_0305 pbp2X 292638..294890 (+) 2253 ACF56039.1 penicillin-binding protein 2X -
  SPG_0306 - 294892..295872 (+) 981 ACF56547.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  SPG_0307 - 296084..296200 (+) 117 ACF54867.1 conserved hypothetical protein -
  SPG_0308 clpC 296481..298586 (+) 2106 ACF55903.1 ATP-dependent Clp protease, ATP-binding subunit, putative Regulator
  SPG_0309 luxS 298882..299364 (-) 483 ACF56338.1 S-ribosylhomocysteine lyase -
  SPG_0310 - 299459..300943 (-) 1485 ACF56783.1 conserved hypothetical protein -
  SPG_0311 dexB 301096..302703 (+) 1608 ACF55107.1 glucan 1,6-alpha-glucosidase -
  SPG_0312 - 302862..303035 (+) 174 ACF56199.1 hypothetical protein -
  SPG_0313 - 303258..303383 (+) 126 ACF56330.1 hypothetical protein -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77593.35 Da        Isoelectric Point: 4.7080

>NTDB_id=20325 SPG_0308 ACF55903.1 296481..298586(+) (clpC) [Streptococcus pneumoniae G54]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=20325 SPG_0308 ACF55903.1 296481..298586(+) (clpC) [Streptococcus pneumoniae G54]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGATCTCTATCAACAACACCACAATGTCATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGATCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ATCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTTAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGATGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA lid domain (AAA_lid_9)

(259-354)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

50.078

91.441

0.458
  clpE Streptococcus mutans UA159

49.221

91.583

0.451
  clpE Streptococcus pneumoniae TIGR4

47.95

90.442

0.434
  clpE Streptococcus pneumoniae Rx1

47.95

90.442

0.434
  clpE Streptococcus pneumoniae D39

47.95

90.442

0.434
  clpE Streptococcus pneumoniae R6

47.95

90.442

0.434
  clpC Bacillus subtilis subsp. subtilis str. 168

44.892

92.154

0.414
  clpC Streptococcus pneumoniae Rx1

42.654

90.3

0.385
  clpC Streptococcus pneumoniae D39

42.654

90.3

0.385
  clpC Streptococcus pneumoniae TIGR4

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMD-9

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMG 18311

42.338

90.3

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.112

88.017

0.379
  clpC Streptococcus mutans UA159

41.909

88.16

0.369

Multiple sequence alignment