Detailed information NTG0020147

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: Spy49_0914
• Genome accession: CP000829
• Coordinates: 910085..910921 (+)
• Length: 278 a.a.
• NCBI ID: ACI61220.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes NZ131
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 905085..915921

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Spy49_0908	-	905603..906007 (+)	405	ACI61214.1	hypothetical protein	-
Spy49_0909c	-	906057..906968 (-)	912	ACI61215.1	hypothetical protein	-
Spy49_0910c	hlyIII	907220..907735 (-)	516	ACI61216.1	Putative hemolysin III	-
Spy49_0911c	-	907732..908172 (-)	441	ACI61217.1	hypothetical protein	-
Spy49_0912	-	908391..909239 (+)	849	ACI61218.1	GTP-binding protein	-
Spy49_0913	rnh	909229..910020 (+)	792	ACI61219.1	Ribonuclease HII	-
Spy49_0914	dprA	910085..910921 (+)	837	ACI61220.1	Putative DNA processing protein	Machinery gene
Spy49_0915	topA	911028..913157 (+)	2130	ACI61221.1	Putative DNA topoisomerase I	-
Spy49_0916c	-	913233..913715 (-)	483	ACI61222.1	Transcriptional regulator, LysR family	-
Spy49_0917c	-	913722..913844 (-)	123	ACI61223.1	Transcriptional regulator, LysR family	-
Spy49_0918	-	914130..914696 (+)	567	ACI61224.1	Regulatory protein	-
Spy49_0919	-	914711..915703 (+)	993	ACI61225.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30987.06 Da
• Isoelectric Point: 9.5635

>NTDB_id=20147 Spy49_0914 ACI61220.1 910085..910921(+) (dprA) [Streptococcus pyogenes NZ131]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRKLQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=20147 Spy49_0914 ACI61220.1 910085..910921(+) (dprA) [Streptococcus pyogenes NZ131]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGAAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367
dprA	Acinetobacter baumannii strain A118	38.202	96.043	0.367
dprA	Acinetobacter baumannii D1279779	37.828	96.043	0.363