Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   WH25_RS00195 Genome accession   NZ_CP017295
Coordinates   46506..47762 (-) Length   418 a.a.
NCBI ID   WP_046164527.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 41506..52762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS00165 (WH25_00165) - 42964..43275 (-) 312 WP_008809966.1 DUF1292 domain-containing protein -
  WH25_RS00170 (WH25_00170) ruvX 43296..43715 (-) 420 WP_008809967.1 Holliday junction resolvase RuvX -
  WH25_RS00175 (WH25_00175) - 43715..43981 (-) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  WH25_RS00180 (WH25_00180) - 44093..44665 (-) 573 WP_045773038.1 SP0191 family lipoprotein -
  WH25_RS00185 (WH25_00185) spx 44811..45209 (-) 399 WP_046164525.1 transcriptional regulator Spx -
  WH25_RS00190 (WH25_00190) recA 45296..46447 (-) 1152 WP_046164526.1 recombinase RecA Machinery gene
  WH25_RS00195 (WH25_00195) cinA 46506..47762 (-) 1257 WP_046164527.1 competence/damage-inducible protein A Machinery gene
  WH25_RS00200 (WH25_00200) - 48032..48442 (+) 411 WP_046164528.1 helix-turn-helix domain-containing protein -
  WH25_RS00205 (WH25_00205) - 48492..49151 (-) 660 WP_046164529.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS00210 (WH25_00210) - 49156..49710 (-) 555 WP_046164530.1 DNA-3-methyladenine glycosylase I -
  WH25_RS00215 (WH25_00215) - 49714..50286 (-) 573 WP_231108794.1 hypothetical protein -
  WH25_RS00220 (WH25_00220) ruvA 50283..50873 (-) 591 WP_046164532.1 Holliday junction branch migration protein RuvA -
  WH25_RS00225 (WH25_00225) - 51043..51546 (+) 504 WP_046164533.1 helix-turn-helix domain-containing protein -
  WH25_RS00230 (WH25_00230) - 51530..52051 (+) 522 WP_046164534.1 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44853.08 Da        Isoelectric Point: 4.7124

>NTDB_id=197390 WH25_RS00195 WP_046164527.1 46506..47762(-) (cinA) [Streptococcus gordonii strain IE35]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELIFDPQAVEKLDHFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIEKQNDPTIAPYAKTGEVTLRLSTKALSQAEADTKFEAVEKEI
LGHKTFEEQSLSEIFYGYGDDNSLAQVAFDLLKSQEKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSWML
DIPLGDLEKHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEGHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=197390 WH25_RS00195 WP_046164527.1 46506..47762(-) (cinA) [Streptococcus gordonii strain IE35]
ATGAAAGCAGAAATTATTGCTGTGGGCACCGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
GAAACTGGCTAGTCTGGGGATTGATGTCTATTTTCAGACAGCTGTAGGGGACAATGAAAATCGTCTCCTCTCTATCCTAG
AGATTGCAAAAGGACGTAGTAATCTGATTATTCTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTGGGACGTGAGCTCATCTTTGATCCTCAGGCTGTGGAAAAGTTGGATCATTTTTTTGCTAGCCGACC
AGATTATGCCCGAACACCCAACAATGAGCGTCAGGCCCAGTTGGTTGAAGGCTCAACTCCTTTACCAAATGCGACCGGCT
TAGCTGTCGGAGGCTTGTTAGAAGCAGACGGAGTGACCTATGTAGTCTTGCCTGGCCCGCCTAGCGAGCTTAAACCTATG
GTCAATAATGAGCTGGTTCCCCTCTTATCCACAGGTCAGAAATTGTACTCACGGGTGCTGCGTTTCTTTGGTATCGGTGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGAGAAACAGAACGACCCCACAATTGCTCCTTATGCAAAGACAGGGG
AAGTTACCCTGCGACTGTCCACCAAGGCCTTGAGTCAGGCAGAAGCTGACACCAAGTTCGAGGCTGTGGAAAAGGAAATT
TTGGGACATAAGACTTTTGAGGAACAGTCTCTATCAGAGATTTTCTATGGCTACGGGGATGACAATTCCTTGGCACAGGT
GGCTTTCGACTTGCTCAAGAGCCAAGAGAAGACAATTTCAGCAGCAGAGAGCCTGACAGCAGGTCTCTTTCAAGCGACTT
TGGCAGATTTTGCTGGAGCTTCAGCTATTTTTTCAGGCGGCTTCGTCACCTATAGCATGGAGGAAAAGAGCTGGATGCTG
GATATCCCGTTGGGAGACCTTGAGAAGCATGGAGTTGTTTCCGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTAGCTGTTAGTCTGACAGGCGTGGCTGGACCAGATTCACTGGAAGGCCATCCAGCAGGGACCG
TTTTTATCGGTTTAGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGTAGCCGGCGAGATGTACGA
AAAATCGCTGTCCTGCACGCCTTTAACCTAGTGCGAAAGACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

78.177

99.761

0.78
  cinA Streptococcus mitis NCTC 12261

77.698

99.761

0.775
  cinA Streptococcus pneumoniae TIGR4

76.499

99.761

0.763
  cinA Streptococcus pneumoniae Rx1

76.499

99.761

0.763
  cinA Streptococcus pneumoniae R6

76.499

99.761

0.763
  cinA Streptococcus pneumoniae D39

76.259

99.761

0.761
  cinA Streptococcus mutans UA159

75.12

100

0.751
  cinA Streptococcus suis isolate S10

54.197

99.761

0.541
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

100

0.464

Multiple sequence alignment