Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   A7J08_RS00895 Genome accession   NZ_CP017088
Coordinates   145960..146997 (+) Length   345 a.a.
NCBI ID   WP_238600014.1    Uniprot ID   A0A3Q8B4X1
Organism   Streptococcus suis strain SRD478     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 140960..151997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS00880 (A7J08_00875) - 143507..143881 (+) 375 WP_024385120.1 DUF1033 family protein -
  A7J08_RS00885 (A7J08_00880) - 143915..144826 (-) 912 Protein_136 S66 peptidase family protein -
  A7J08_RS00890 (A7J08_00885) comYA 145098..146048 (+) 951 WP_053867353.1 competence type IV pilus ATPase ComGA Machinery gene
  A7J08_RS00895 (A7J08_00890) comYB 145960..146997 (+) 1038 WP_238600014.1 competence type IV pilus assembly protein ComGB Machinery gene
  A7J08_RS00900 (A7J08_00895) comYC 146999..147280 (+) 282 WP_053866667.1 competence type IV pilus major pilin ComGC Machinery gene
  A7J08_RS00905 (A7J08_00900) comGD 147261..147668 (+) 408 WP_053866668.1 competence type IV pilus minor pilin ComGD -
  A7J08_RS00910 (A7J08_00905) comYE 147640..147933 (+) 294 WP_053866669.1 competence type IV pilus minor pilin ComGE Machinery gene
  A7J08_RS00915 (A7J08_00910) comGF/cglF 147920..148354 (+) 435 WP_053866670.1 competence type IV pilus minor pilin ComGF Machinery gene
  A7J08_RS00920 (A7J08_00915) comGG 148332..148745 (+) 414 WP_053866671.1 competence type IV pilus minor pilin ComGG -
  A7J08_RS00925 (A7J08_00920) comYH 148795..149748 (+) 954 WP_053866672.1 class I SAM-dependent methyltransferase Machinery gene
  A7J08_RS00930 (A7J08_00925) - 149798..150985 (+) 1188 WP_053866673.1 acetate kinase -
  A7J08_RS00940 (A7J08_00930) - 151299..151850 (+) 552 WP_053866674.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38867.86 Da        Isoelectric Point: 8.8903

>NTDB_id=195380 A7J08_RS00895 WP_238600014.1 145960..146997(+) (comYB) [Streptococcus suis strain SRD478]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTLVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLCGLSLVAILAGLVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=195380 A7J08_RS00895 WP_238600014.1 145960..146997(+) (comYB) [Streptococcus suis strain SRD478]
ATGAACAAATTGATTGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTTCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTACACTCTGGTCTTGTCAGATGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCAGATTTGCGTTTTTCAGATGCGGTGGTCACGCAGGTGGCACTGGCAGAAGTTCATGGCAACACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAACTGATTGAGGTGGCGACCTACCCGATTATCTTGC
TTGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAATTATCTTCTGCCTCAGTTGGAGGAAGGCAATGCAGCGACGGTG
CTGATCAATCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGATCTTAGCTGGTCTTGTTTGGTT
TCGCAAAACTAACAAAATCAAGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCTAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGAGAGATTGGACAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTTATCTACGCAGCTATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(34-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q8B4X1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.158

99.13

0.626
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment