Detailed information NTG0194054

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: BFM96_RS07755
• Genome accession: NZ_CP016953
• Coordinates: 1657412..1658260 (+)
• Length: 282 a.a.
• NCBI ID: WP_188595277.1
• Uniprot ID: A0A917EEG6
• Organism: Streptococcus himalayensis strain HTS2
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1652412..1663260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFM96_RS07730	-	1652758..1654428 (+)	1671	WP_068992609.1	formate--tetrahydrofolate ligase	-
BFM96_RS07735	-	1654520..1655134 (+)	615	WP_068992612.1	DUF5052 family protein	-
BFM96_RS07740	-	1655131..1655877 (+)	747	WP_068992615.1	hypothetical protein	-
BFM96_RS07745	-	1655871..1656368 (+)	498	WP_068992618.1	GNAT family N-acetyltransferase	-
BFM96_RS07750	-	1656371..1657024 (+)	654	WP_068992621.1	DNA alkylation repair protein	-
BFM96_RS07755	dprA/cilB/dalA	1657412..1658260 (+)	849	WP_188595277.1	DNA-processing protein DprA	Machinery gene
BFM96_RS07760	topA	1658354..1660444 (+)	2091	WP_068994263.1	type I DNA topoisomerase	-
BFM96_RS07765	trmFO	1660659..1662005 (+)	1347	WP_068992624.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
BFM96_RS07770	-	1662095..1662535 (+)	441	WP_068992626.1	MerR family transcriptional regulator	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31317.10 Da
• Isoelectric Point: 6.3473

>NTDB_id=194054 BFM96_RS07755 WP_188595277.1 1657412..1658260(+) (dprA/cilB/dalA) [Streptococcus himalayensis strain HTS2]
MEITNFFIYKLKKAGLSNQEVINVLSYVEIQAKEVSVRNMAIVSKCRNPALFIERYKNQNDELLKEEFEKFPSFSIMDDV
YPWDLSEIYNPPVLLFYQGNLDLLNLPKLAVVGSRDCSQDGAQAVKKIITELQNEIVIVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVYYPKANKKLQKYIGENHLVLSEYGPGEQPLKFHFPERNRIIAGLSRGVVVAEAKMRSGSLITCERAMEE
GRDVFAIPGSIITGKSDGCHHLIQEGAKCITSGSDVLLEFQF

Nucleotide

• Length: 849 bp

>NTDB_id=194054 BFM96_RS07755 WP_188595277.1 1657412..1658260(+) (dprA/cilB/dalA) [Streptococcus himalayensis strain HTS2]
ATGGAAATTACAAATTTTTTTATTTATAAATTGAAAAAAGCAGGCTTGTCCAATCAGGAAGTGATCAATGTTTTGAGCTA
TGTCGAAATTCAGGCAAAAGAAGTCAGTGTTCGAAATATGGCAATTGTCTCCAAGTGCCGCAATCCTGCTCTTTTTATCG
AACGTTACAAAAATCAAAATGACGAGTTATTGAAAGAAGAGTTTGAAAAGTTTCCTTCGTTTTCAATCATGGATGACGTG
TATCCATGGGATTTAAGTGAAATTTATAATCCACCTGTCTTGCTCTTTTATCAAGGAAATCTAGATTTATTGAATTTGCC
CAAACTAGCGGTAGTCGGTAGTCGTGACTGTAGCCAAGACGGAGCACAAGCCGTTAAAAAGATTATTACGGAATTGCAAA
ATGAAATCGTGATTGTCAGTGGGCTTGCTAAAGGCATTGATACAGCTGCCCACATGGCTGCGCTCCAAAATGGGGGACGA
ACTATTGCCGTTATCGGGACAGGATTGGATGTCTATTACCCAAAAGCTAACAAAAAATTGCAAAAGTATATTGGAGAAAA
TCATCTGGTGCTTAGCGAATATGGTCCAGGTGAGCAACCCTTGAAATTCCATTTTCCAGAGCGAAATCGAATTATCGCTG
GCTTGAGCCGCGGGGTCGTTGTGGCAGAGGCTAAAATGCGTTCTGGAAGCCTCATTACCTGTGAGCGAGCGATGGAAGAA
GGGCGAGATGTATTTGCCATTCCAGGATCCATTATCACTGGGAAAAGTGATGGGTGCCATCATTTGATTCAAGAGGGTGC
AAAGTGCATTACATCAGGCTCTGACGTCCTTTTAGAGTTCCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	75.177	100	0.752
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	74.823	100	0.748
dprA/cilB/dalA	Streptococcus pneumoniae D39	74.823	100	0.748
dprA/cilB/dalA	Streptococcus pneumoniae R6	74.823	100	0.748
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	74.823	100	0.748
dprA/cilB/dalA	Streptococcus mitis SK321	74.468	100	0.745
dprA	Streptococcus mutans UA159	66.429	99.291	0.66
dprA	Lactococcus lactis subsp. cremoris KW2	58.929	99.291	0.585
dprA	Legionella pneumophila strain ERS1305867	43.568	85.461	0.372
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362