Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BFM96_RS02970 Genome accession   NZ_CP016953
Coordinates   597974..599149 (-) Length   391 a.a.
NCBI ID   WP_068990089.1    Uniprot ID   A0A917A420
Organism   Streptococcus himalayensis strain HTS2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 592974..604149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS02945 - 593295..593666 (-) 372 WP_068990076.1 helix-turn-helix domain-containing protein -
  BFM96_RS02950 - 594071..594262 (-) 192 WP_068990079.1 DUF951 domain-containing protein -
  BFM96_RS02955 dnaN 594262..595398 (-) 1137 WP_068990081.1 DNA polymerase III subunit beta -
  BFM96_RS02960 dnaA 595555..596916 (-) 1362 WP_068990083.1 chromosomal replication initiator protein DnaA -
  BFM96_RS02965 spo0J 597144..597911 (-) 768 WP_068990086.1 ParB/RepB/Spo0J family partition protein Regulator
  BFM96_RS02970 htrA 597974..599149 (-) 1176 WP_068990089.1 S1C family serine protease Regulator
  BFM96_RS02975 rlmH 599354..599833 (+) 480 WP_068990092.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BFM96_RS10785 - 600115..600249 (+) 135 WP_083201733.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BFM96_RS02985 comD/comD2 600265..601587 (+) 1323 WP_068990095.1 GHKL domain-containing protein Regulator
  BFM96_RS02990 comE/comE2 601584..602327 (+) 744 WP_068990101.1 competence system response regulator transcription factor ComE Regulator
  BFM96_RS11430 - 602555..602680 (+) 126 WP_262981929.1 hypothetical protein -

Sequence

Protein


Download         Length: 391 a.a.        Molecular weight: 41335.27 Da        Isoelectric Point: 4.9590

>NTDB_id=194002 BFM96_RS02970 WP_068990089.1 597974..599149(-) (htrA) [Streptococcus himalayensis strain HTS2]
MKHSSNFFKKIMQLLTVLVVGFVGGVAGTYLTNPSPKQSTTTTTTAGKTVPTSYKNTTSTSEAVDKVKNAVVSVITYAET
NKQGFLFGNDNADSSQQVASEGSGVIYKKEGKYAYLVTNTHVINGASKVDIRLADGKKVAGDIVGTDVYSDISVVRISSE
EVDTVAEFGDSDNLTVGETAIAIGSPLGSDYANTVTQGIVSSLNRTVSLRAEDGQAISTQAIQTDTAINPGNSGGPLINI
QGQVIGINSSKIATDGQNSVEGLGFAIPANDVQNIIKQLEENGSVIRPALGIQMIDMSHITSSDLARLNLPDKIRNGVIV
RSAQTGMPAEGKLEKYDVITKIDDQEISSTTDLQSALYKHSIGDEISITLYRNGKEKTVSITLTKSTQDLS

Nucleotide


Download         Length: 1176 bp        

>NTDB_id=194002 BFM96_RS02970 WP_068990089.1 597974..599149(-) (htrA) [Streptococcus himalayensis strain HTS2]
ATGAAACATTCTTCAAATTTCTTCAAAAAAATCATGCAACTACTCACTGTTCTTGTGGTCGGATTTGTCGGAGGAGTGGC
AGGAACCTATCTGACGAATCCATCCCCTAAGCAGTCCACCACAACAACGACTACTGCTGGAAAGACTGTTCCGACTAGTT
ACAAGAATACAACCTCAACGTCAGAAGCTGTGGATAAAGTCAAAAATGCAGTTGTATCTGTCATTACTTATGCTGAAACG
AACAAGCAAGGTTTTCTATTTGGCAATGACAATGCTGATTCTTCCCAACAAGTGGCTAGCGAGGGATCTGGCGTTATTTA
TAAAAAAGAAGGAAAATATGCCTATTTAGTGACCAATACGCACGTTATCAATGGTGCTTCTAAAGTAGATATTCGTCTAG
CAGATGGCAAGAAAGTAGCAGGTGACATCGTTGGAACAGATGTTTATTCAGATATTTCTGTTGTGCGTATTAGCTCTGAG
GAAGTTGATACTGTCGCTGAATTCGGTGATTCAGACAATCTGACTGTCGGAGAAACTGCTATTGCGATTGGAAGCCCCCT
TGGCTCAGATTATGCCAATACCGTTACACAGGGCATTGTCTCTAGTTTAAATAGAACCGTATCCCTAAGAGCAGAAGACG
GACAAGCCATCTCGACACAAGCCATTCAAACCGATACAGCAATCAACCCAGGAAATTCTGGAGGTCCTCTCATCAACATC
CAAGGACAAGTCATTGGAATCAATTCTAGTAAGATTGCAACAGATGGACAAAATTCTGTCGAAGGACTTGGTTTTGCAAT
CCCAGCCAACGATGTTCAAAATATCATCAAACAGTTAGAAGAAAATGGCAGCGTCATCCGTCCAGCACTTGGAATCCAAA
TGATTGATATGAGCCATATTACCAGCTCTGATTTAGCTCGTCTCAATCTTCCTGATAAGATCAGAAATGGAGTCATTGTC
CGCTCTGCTCAAACAGGGATGCCGGCTGAAGGAAAATTAGAGAAATATGATGTCATTACCAAAATTGACGACCAAGAAAT
TTCTTCCACCACTGACCTCCAATCCGCCCTTTACAAGCATAGTATTGGAGATGAGATTTCTATCACCCTTTACCGAAATG
GAAAAGAAAAAACAGTTTCTATCACATTAACCAAATCAACCCAGGACTTATCTTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(102-247)

Peptidase family M50 (Peptidase_M50)

(234-387)

PDZ domain (PDZ_2)

(288-383)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

70.38

100

0.711
  htrA Streptococcus mitis NCTC 12261

69.388

100

0.696
  htrA Streptococcus pneumoniae Rx1

68.622

100

0.688
  htrA Streptococcus pneumoniae D39

68.622

100

0.688
  htrA Streptococcus pneumoniae R6

68.622

100

0.688
  htrA Streptococcus pneumoniae TIGR4

68.622

100

0.688
  htrA Streptococcus mutans UA159

53.283

100

0.54

Multiple sequence alignment