Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   BFM96_RS02985 Genome accession   NZ_CP016953
Coordinates   600265..601587 (+) Length   440 a.a.
NCBI ID   WP_068990095.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 595265..606587
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS02960 dnaA 595555..596916 (-) 1362 WP_068990083.1 chromosomal replication initiator protein DnaA -
  BFM96_RS02965 spo0J 597144..597911 (-) 768 WP_068990086.1 ParB/RepB/Spo0J family partition protein Regulator
  BFM96_RS02970 htrA 597974..599149 (-) 1176 WP_068990089.1 S1C family serine protease Regulator
  BFM96_RS02975 rlmH 599354..599833 (+) 480 WP_068990092.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BFM96_RS10785 - 600115..600249 (+) 135 WP_083201733.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BFM96_RS02985 comD/comD2 600265..601587 (+) 1323 WP_068990095.1 GHKL domain-containing protein Regulator
  BFM96_RS02990 comE/comE2 601584..602327 (+) 744 WP_068990101.1 competence system response regulator transcription factor ComE Regulator
  BFM96_RS11430 - 602555..602680 (+) 126 WP_262981929.1 hypothetical protein -
  BFM96_RS03005 - 602833..605421 (-) 2589 WP_068990103.1 YfhO family protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51190.64 Da        Isoelectric Point: 5.5424

>NTDB_id=194003 BFM96_RS02985 WP_068990095.1 600265..601587(+) (comD/comD2) [Streptococcus himalayensis strain HTS2]
MNMNILYFVLLFIDILSFTLIYKKICKEKKVNLPFTFLCFGFLLLKDIIGYIGVLAWYSFYVIEPLFIYFYLRKYEKDTK
LIAAFLTMLVYQAALTSETFLSVIISSVTGDDFVTNYSGIYFIAIDLLSLFIILKLIDYFDINIYKFLEPYFREYLRTVT
SFLLGVHLFLNISHWISNFTTFNSFASMITTICFLAFIATLLYLKSIREKFEKEVELEQKKKEQLQLQQYTDEIVDLYNE
IKGFRHDYGGMLVSFQAAIDSQNMAEVERIYQDVLVRANEKLSSDRYTSFDLNNVGDSALRSMLTQTLFKAREHQIELTF
EIKDYVGKLPIQLLDLVRMTSILLNNAVEGAAESIAKTLNVSLVDLEGEVILVIQNSRKDQNLQLNSVYQRNFSTKGEGR
GTGLTTVKEMIDQYEGLVLDTEITKEHFTQVLRIRKVYRL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=194003 BFM96_RS02985 WP_068990095.1 600265..601587(+) (comD/comD2) [Streptococcus himalayensis strain HTS2]
ATAAATATGAATATACTATATTTTGTCTTACTATTTATAGATATTTTATCATTTACATTAATTTATAAAAAAATTTGTAA
AGAGAAGAAAGTAAATCTTCCCTTTACTTTTCTGTGCTTTGGATTTCTATTGCTAAAAGATATTATAGGATATATAGGGG
TGCTAGCTTGGTATTCTTTTTATGTTATTGAACCTCTGTTTATTTACTTTTATTTACGGAAATATGAGAAAGATACGAAA
TTAATTGCTGCTTTTTTAACTATGCTAGTCTATCAGGCAGCATTAACCTCAGAAACCTTCTTGTCAGTAATCATATCATC
AGTGACTGGAGATGATTTTGTAACAAATTATTCTGGCATTTACTTTATTGCAATTGATTTGTTATCATTGTTTATTATTT
TAAAGTTAATTGATTATTTTGACATTAATATCTATAAATTTTTAGAACCGTACTTTAGGGAGTATTTGAGAACAGTAACC
TCTTTTTTACTTGGAGTTCATCTTTTTTTGAACATTTCTCACTGGATTAGTAATTTTACAACTTTCAATAGTTTTGCAAG
TATGATAACCACTATTTGCTTTTTGGCATTTATTGCTACACTCCTATACTTAAAGTCTATTCGTGAAAAATTTGAAAAAG
AAGTGGAGTTGGAGCAAAAAAAGAAAGAGCAGCTACAATTGCAGCAATATACGGATGAAATTGTGGATTTGTATAATGAA
ATTAAAGGTTTTCGCCATGATTATGGAGGGATGCTGGTCAGTTTTCAAGCAGCTATTGACAGTCAAAATATGGCAGAGGT
TGAGCGAATTTATCAAGATGTGTTGGTTCGTGCAAATGAAAAATTGAGTTCTGATAGATACACTTCGTTTGATTTGAATA
ATGTGGGAGATTCAGCTTTGCGAAGTATGCTTACTCAAACCTTGTTCAAGGCACGTGAGCATCAGATTGAGTTGACATTT
GAAATCAAAGATTATGTTGGAAAATTGCCAATTCAACTTCTTGATTTGGTTCGGATGACGAGTATTTTGTTAAATAATGC
GGTTGAAGGTGCGGCAGAAAGTATTGCCAAAACCCTAAATGTTTCCTTGGTTGATTTGGAGGGAGAAGTAATTTTAGTCA
TTCAAAATTCACGCAAGGATCAAAACTTACAATTAAACTCTGTCTATCAACGGAATTTTTCTACCAAAGGTGAAGGTCGT
GGGACTGGTTTGACGACTGTTAAGGAAATGATTGACCAATACGAAGGATTGGTTTTAGATACAGAAATCACAAAAGAGCA
TTTTACACAAGTGTTAAGAATTAGAAAGGTTTATCGATTATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

50

100

0.507
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.737

86.364

0.473
  comD/comD2 Streptococcus pneumoniae TIGR4

42.188

100

0.43
  comD/comD1 Streptococcus pneumoniae D39

42.534

100

0.427
  comD/comD1 Streptococcus pneumoniae Rx1

42.534

100

0.427
  comD/comD1 Streptococcus pneumoniae R6

42.534

100

0.427
  comD Streptococcus mitis NCTC 12261

42.342

100

0.427
  comD Streptococcus mitis SK321

41.425

100

0.423

Multiple sequence alignment