Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   clem_RS06490 Genome accession   NZ_CP016397
Coordinates   1490182..1491231 (-) Length   349 a.a.
NCBI ID   WP_094090887.1    Uniprot ID   A0A222P1Y9
Organism   Legionella clemsonensis strain CDC-D5610     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1485182..1496231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  clem_RS06465 (clem_06570) - 1485472..1485930 (+) 459 WP_094090884.1 hypothetical protein -
  clem_RS06470 (clem_06575) - 1485940..1486527 (+) 588 WP_198333202.1 hypothetical protein -
  clem_RS06475 (clem_06580) - 1486772..1487914 (+) 1143 WP_094090885.1 Fic family protein -
  clem_RS06480 (clem_06585) - 1488174..1489193 (-) 1020 WP_198333205.1 carbonic anhydrase -
  clem_RS06485 (clem_06590) - 1489319..1490176 (-) 858 WP_094090886.1 A24 family peptidase -
  clem_RS06490 (clem_06595) pilC 1490182..1491231 (-) 1050 WP_094090887.1 type II secretion system F family protein Machinery gene
  clem_RS06495 (clem_06600) pilB 1491231..1492931 (-) 1701 WP_094090888.1 type IV-A pilus assembly ATPase PilB Machinery gene
  clem_RS06500 (clem_06605) - 1493034..1493264 (+) 231 WP_094090889.1 hypothetical protein -
  clem_RS06505 (clem_06610) - 1493413..1494150 (+) 738 WP_094090890.1 class I SAM-dependent methyltransferase -
  clem_RS06510 (clem_06615) - 1494320..1494646 (+) 327 WP_094090891.1 DUF1820 family protein -
  clem_RS06515 (clem_06620) - 1494670..1495230 (+) 561 WP_094090892.1 hypoxanthine-guanine phosphoribosyltransferase -
  clem_RS06520 (clem_06625) - 1495399..1496115 (-) 717 WP_232505579.1 murein L,D-transpeptidase family protein -

Sequence

Protein


Download         Length: 349 a.a.        Molecular weight: 38520.74 Da        Isoelectric Point: 9.3911

>NTDB_id=187968 clem_RS06490 WP_094090887.1 1490182..1491231(-) (pilC) [Legionella clemsonensis strain CDC-D5610]
MLNIKKINKHEITIFSRQMATMIAAGLPLIQAFDVIEKGAVNNYLKKLVATIKYDIEASYTFAEALQKHPAYFSSLFCSL
IEAGEKSGALAIMLNKVATYQEKLDTVRKKITRIMAYPLTVLLMALLITVGLLLFVIPQFAVLFNTFGAELPFLTQGVIY
LSHLLQNHGFFILGTSMTLIGGVFYSRKNFPHFSHYWDKALLKLPVLGRFLVQSIIVRFSRTLAVTLSAGLPLMQALHAA
GNVTGNSVYQLASYRIQDAVSYGQSLRLALENAGIFPALVIQMIAIGEESGTLEAMLNKIADYYEGEINNAVESLNILLE
PFIMAILGIVIGTLLLAVYVPIFKLGSIM

Nucleotide


Download         Length: 1050 bp        

>NTDB_id=187968 clem_RS06490 WP_094090887.1 1490182..1491231(-) (pilC) [Legionella clemsonensis strain CDC-D5610]
ATGTTGAATATAAAGAAAATTAATAAACACGAGATTACTATTTTTAGCCGACAAATGGCAACCATGATTGCGGCCGGCCT
CCCTCTAATACAAGCTTTCGATGTTATAGAAAAAGGAGCTGTAAACAATTATTTAAAAAAACTGGTCGCAACAATAAAAT
ACGACATCGAGGCCAGCTATACCTTTGCAGAGGCGCTTCAAAAGCACCCTGCTTACTTTAGTTCATTATTTTGTAGTTTA
ATTGAGGCCGGAGAAAAATCTGGTGCTCTGGCTATAATGCTTAATAAAGTAGCTACTTATCAGGAAAAGCTTGACACAGT
TCGCAAAAAAATTACAAGAATCATGGCTTATCCACTTACAGTCTTGTTGATGGCGCTACTAATTACTGTGGGACTTTTAT
TATTTGTAATTCCGCAATTTGCTGTATTGTTTAATACCTTTGGAGCTGAGCTACCTTTTTTAACGCAAGGGGTTATTTAT
CTTTCTCATCTCTTGCAGAACCATGGGTTTTTCATTCTAGGAACATCGATGACGCTCATAGGAGGAGTTTTTTATTCCAG
AAAAAATTTTCCCCATTTTTCCCATTACTGGGATAAGGCTTTACTGAAGTTACCTGTGTTGGGGAGGTTTTTAGTACAAT
CCATAATTGTCCGTTTTTCACGCACATTAGCCGTGACTCTTTCTGCAGGATTACCCCTAATGCAAGCATTGCATGCTGCT
GGCAATGTAACAGGTAATAGCGTCTATCAATTAGCGAGCTACCGTATTCAAGATGCAGTATCTTATGGGCAATCTTTACG
CTTGGCTCTGGAAAACGCTGGTATTTTTCCTGCCCTGGTTATTCAGATGATTGCAATAGGCGAAGAGTCAGGAACGCTTG
AAGCCATGCTGAATAAAATTGCTGATTATTATGAAGGTGAAATAAATAATGCTGTTGAATCACTTAATATTTTATTAGAG
CCCTTTATCATGGCAATATTAGGTATCGTGATTGGAACCCTCTTACTGGCAGTGTATGTTCCGATTTTTAAACTTGGCTC
AATTATGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(15-138)

Type II secretion system (T2SS), protein F (T2SSF)

(219-341)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A222P1Y9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

52.187

98.281

0.513
  pilC Acinetobacter baylyi ADP1

45.217

98.854

0.447
  pilC Acinetobacter baumannii D1279779

44.348

98.854

0.438
  pilC Pseudomonas stutzeri DSM 10701

43.103

99.713

0.43
  pilC Vibrio campbellii strain DS40M4

38.728

99.14

0.384
  pilG Neisseria meningitidis 44/76-A

36.963

100

0.37
  pilG Neisseria gonorrhoeae MS11

37.391

98.854

0.37
  pilC Vibrio cholerae strain A1552

36.628

98.567

0.361

Multiple sequence alignment