Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A6P53_RS12240 Genome accession   NZ_CP015516
Coordinates   2739866..2741113 (-) Length   415 a.a.
NCBI ID   WP_063627646.1    Uniprot ID   -
Organism   Enterococcus hirae strain R17     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2734866..2746113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6P53_RS12230 (A6P53_12235) rny 2736594..2738150 (-) 1557 WP_010720620.1 ribonuclease Y -
  A6P53_RS12235 (A6P53_12240) recA 2738720..2739760 (-) 1041 WP_010720621.1 recombinase RecA Machinery gene
  A6P53_RS12240 (A6P53_12245) cinA 2739866..2741113 (-) 1248 WP_063627646.1 competence/damage-inducible protein A Machinery gene
  A6P53_RS12245 (A6P53_12250) pgsA 2741429..2742007 (-) 579 WP_010720623.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A6P53_RS12250 (A6P53_12255) - 2742176..2743066 (-) 891 WP_010720624.1 RodZ domain-containing protein -
  A6P53_RS12255 (A6P53_12260) yfmH 2743297..2744586 (-) 1290 WP_010720625.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  A6P53_RS12260 (A6P53_12265) yfmF 2744579..2745847 (-) 1269 WP_010737266.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45719.05 Da        Isoelectric Point: 4.7334

>NTDB_id=180286 A6P53_RS12240 WP_063627646.1 2739866..2741113(-) (cinA) [Enterococcus hirae strain R17]
MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYQTVVGDNPDRLESLLQLAETRSDLIILCGGLGPTEDDLTKEV
TAKHLGEELIQNTEGYKKLLAFFETTKRKMTENNLQQSQIIDGGIALPNRTGLALGTFYQTADHVYLLLPGPPSELKPMF
IEQARPLLEQNFPSEEMLISKVLRFYGIGESQLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDKHAGNQALLALE
EKVLARVGEYFYGYGDDNSLPKVVVELLKERNQTITAAESLTAGAFQSALGEISGVSQVFSGGFITYSLETKSEFLHIDD
ALLKQHGTVSQECAEQMAIQARNLAKTDYAISFTGVAGPDTLEGQPAGTVWIAVATSEGEVISQKYQFTRDRSHIRSSAV
MQGFDLIRRQLLRKK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=180286 A6P53_RS12240 WP_063627646.1 2739866..2741113(-) (cinA) [Enterococcus hirae strain R17]
ATGAAATCAGAAATCATAGCAGTAGGGACAGAACTTTTATTAGGACAAGTAGTCAACACGAATGCCACGTTTTTATCCGA
ACAGTTAGCAGACCTCGGGATTGATGTGTATTATCAAACGGTGGTTGGTGATAATCCCGACCGCTTAGAATCATTACTCC
AATTAGCAGAAACCAGAAGTGACTTGATCATTTTATGTGGAGGGTTGGGACCGACAGAAGACGACCTGACGAAAGAAGTT
ACTGCGAAACATCTAGGGGAAGAATTGATCCAAAACACCGAAGGCTATAAAAAATTGTTAGCATTTTTTGAAACGACCAA
GCGTAAAATGACTGAAAACAATTTACAACAATCACAAATCATCGATGGGGGGATTGCTTTACCTAATCGCACAGGCTTAG
CATTAGGTACGTTCTATCAAACAGCAGACCATGTCTATCTCTTGTTACCTGGACCACCGAGCGAATTAAAGCCAATGTTC
ATTGAACAAGCTCGCCCATTATTGGAGCAAAACTTTCCATCTGAAGAAATGCTGATCTCAAAAGTTTTACGTTTTTACGG
TATCGGGGAATCCCAACTAGTCACAGAATTAAAAGACTTGATTGAAACACAGATCAACCCAACGATTGCCCCTTACGCAA
AACCTAACGAAGTCACTTTACGATTAACTGTGAAGACCAAAGACAAACATGCAGGAAACCAAGCCTTACTTGCTTTGGAA
GAAAAAGTATTGGCGAGAGTAGGTGAGTACTTCTATGGATATGGTGATGATAATTCATTGCCTAAAGTGGTCGTAGAATT
ATTAAAGGAAAGAAACCAAACAATAACTGCAGCAGAAAGTTTGACTGCTGGAGCCTTTCAATCAGCTTTGGGAGAGATCT
CTGGTGTTTCTCAAGTCTTCTCAGGAGGCTTCATTACCTATTCTTTAGAAACTAAATCAGAATTTTTACACATCGATGAT
GCACTATTGAAGCAGCATGGAACCGTCAGCCAAGAATGTGCAGAACAAATGGCTATCCAAGCACGTAATTTAGCAAAAAC
AGATTATGCGATTTCGTTTACTGGAGTGGCTGGACCAGATACCTTAGAAGGACAGCCAGCTGGAACAGTTTGGATCGCGG
TTGCAACAAGTGAAGGGGAGGTCATTTCGCAGAAATACCAATTTACCAGAGACCGTTCTCATATAAGGAGTAGCGCAGTA
ATGCAAGGATTTGATCTCATTAGAAGACAACTATTAAGAAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-411)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.589

100

0.54
  cinA Streptococcus pneumoniae TIGR4

52.619

100

0.533
  cinA Streptococcus pneumoniae Rx1

52.381

100

0.53
  cinA Streptococcus mitis SK321

52.381

100

0.53
  cinA Streptococcus pneumoniae R6

52.381

100

0.53
  cinA Streptococcus pneumoniae D39

52.381

100

0.53
  cinA Streptococcus mitis NCTC 12261

51.905

100

0.525
  cinA Bacillus subtilis subsp. subtilis str. 168

47.458

99.518

0.472
  cinA Streptococcus suis isolate S10

43.333

100

0.439

Multiple sequence alignment