Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A4V06_RS01150 Genome accession   NZ_CP015410
Coordinates   244174..245418 (-) Length   414 a.a.
NCBI ID   WP_065536143.1    Uniprot ID   -
Organism   Enterococcus faecalis strain KB1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 239174..250418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4V06_RS01125 (A4V06_13790) - 239646..240017 (-) 372 WP_002354866.1 RicAFT regulatory complex protein RicA family protein -
  A4V06_RS01130 (A4V06_13795) - 240105..240902 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  A4V06_RS01135 (A4V06_13800) rny 241062..242618 (-) 1557 WP_002354863.1 ribonuclease Y -
  A4V06_RS01145 (A4V06_13805) recA 243015..244061 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  A4V06_RS01150 (A4V06_13810) cinA 244174..245418 (-) 1245 WP_065536143.1 competence/damage-inducible protein A Machinery gene
  A4V06_RS01155 (A4V06_13815) - 245610..246809 (+) 1200 WP_065536144.1 hypothetical protein -
  A4V06_RS01160 (A4V06_13820) - 246889..247518 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  A4V06_RS01165 (A4V06_13825) - 247577..248002 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  A4V06_RS01170 (A4V06_13830) - 248091..248474 (-) 384 WP_002354850.1 YccF domain-containing protein -
  A4V06_RS01175 (A4V06_13835) - 248638..249429 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45235.37 Da        Isoelectric Point: 4.6698

>NTDB_id=179254 A4V06_RS01150 WP_065536143.1 244174..245418(-) (cinA) [Enterococcus faecalis strain KB1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDVFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAIM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=179254 A4V06_RS01150 WP_065536143.1 244174..245418(-) (cinA) [Enterococcus faecalis strain KB1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTTCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGACCTTTATTGATTGATGTGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCCGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGATTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGATTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437

Multiple sequence alignment