Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A6F60_RS08280 Genome accession   NZ_CP015338
Coordinates   1695611..1696861 (+) Length   416 a.a.
NCBI ID   WP_011667974.1    Uniprot ID   M5AZ98
Organism   Levilactobacillus brevis strain 100D8     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1690611..1701861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6F60_RS08260 (A6F60_08190) yfmF 1691325..1692620 (+) 1296 WP_082265224.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  A6F60_RS08265 (A6F60_08195) yfmH 1692598..1693887 (+) 1290 WP_021742877.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  A6F60_RS08270 (A6F60_08200) - 1694001..1694906 (+) 906 WP_024855103.1 helix-turn-helix domain-containing protein -
  A6F60_RS08275 (A6F60_08205) pgsA 1694968..1695555 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A6F60_RS08280 (A6F60_08210) cinA 1695611..1696861 (+) 1251 WP_011667974.1 competence/damage-inducible protein A Machinery gene
  A6F60_RS08285 (A6F60_08215) recA 1696955..1698088 (+) 1134 WP_011667973.1 recombinase RecA Machinery gene
  A6F60_RS12720 - 1698171..1698323 (-) 153 WP_011667972.1 hypothetical protein -
  A6F60_RS08290 (A6F60_08220) rny 1698651..1700210 (+) 1560 WP_011667971.1 ribonuclease Y -
  A6F60_RS08295 (A6F60_08225) - 1700342..1701136 (+) 795 WP_011667970.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44778.88 Da        Isoelectric Point: 5.2849

>NTDB_id=178484 A6F60_RS08280 WP_011667974.1 1695611..1696861(+) (cinA) [Levilactobacillus brevis strain 100D8]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=178484 A6F60_RS08280 WP_011667974.1 1695611..1696861(+) (cinA) [Levilactobacillus brevis strain 100D8]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGACGGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGCACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGACAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AZ98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445

Multiple sequence alignment