Detailed information NTG0178277

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: V471_RS02000
• Genome accession: NZ_CP015283
• Coordinates: 395139..396080 (-)
• Length: 313 a.a.
• NCBI ID: WP_002887018.1
• Uniprot ID: A0AAW6D6G7
• Organism: Streptococcus salivarius strain ATCC 25975
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	396114..397592	395139..396080	flank	34

Gene organization within MGE regions

Location: 395139..397592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V471_RS02000 (V471_02005)	comGA/cglA/cilD	395139..396080 (-)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
V471_RS02005 (V471_02010)	-	396114..397592 (-)	1479	WP_084871058.1	IS1182 family transposase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35283.31 Da
• Isoelectric Point: 5.7041

>NTDB_id=178277 V471_RS02000 WP_002887018.1 395139..396080(-) (comGA/cglA/cilD) [Streptococcus salivarius strain ATCC 25975]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide

• Length: 942 bp

>NTDB_id=178277 V471_RS02000 WP_002887018.1 395139..396080(-) (comGA/cglA/cilD) [Streptococcus salivarius strain ATCC 25975]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTAGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGAGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGTGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGAT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGATCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTTCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTGCGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGTCATTCGTCAACCAGTTGGAACCAGCAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.916	99.361	0.655
comYA	Streptococcus mutans UA159	65.176	100	0.652
comYA	Streptococcus mutans UA140	65.176	100	0.652
comGA/cglA/cilD	Streptococcus pneumoniae D39	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae R6	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	64.63	99.361	0.642
comYA	Streptococcus gordonii str. Challis substr. CH1	62.939	100	0.629
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	60.897	99.681	0.607
comGA	Lactococcus lactis subsp. cremoris KW2	51.447	99.361	0.511
comGA	Latilactobacillus sakei subsp. sakei 23K	41.697	86.581	0.361