Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NX99_RS06510 Genome accession   NZ_CP015282
Coordinates   1454518..1455783 (-) Length   421 a.a.
NCBI ID   WP_084915128.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1449518..1460783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS06500 (NX99_06370) spx 1452771..1453169 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  NX99_RS06505 (NX99_06375) recA 1453338..1454477 (-) 1140 WP_002886327.1 recombinase RecA Machinery gene
  NX99_RS06510 (NX99_06380) cinA 1454518..1455783 (-) 1266 WP_084915128.1 competence/damage-inducible protein A Machinery gene
  NX99_RS06515 (NX99_06385) - 1455880..1456434 (-) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  NX99_RS06520 (NX99_06390) ruvA 1456443..1457033 (-) 591 WP_002886323.1 Holliday junction branch migration protein RuvA -
  NX99_RS06525 (NX99_06395) - 1457191..1457412 (-) 222 WP_002886321.1 hypothetical protein -
  NX99_RS06530 (NX99_06400) mutL 1457543..1459486 (-) 1944 WP_084915129.1 DNA mismatch repair endonuclease MutL -
  NX99_RS06535 (NX99_06405) - 1459536..1459841 (-) 306 WP_004181965.1 hypothetical protein -
  NX99_RS06540 (NX99_06410) - 1460020..1460457 (+) 438 WP_004181975.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45639.83 Da        Isoelectric Point: 5.3184

>NTDB_id=178228 NX99_RS06510 WP_084915128.1 1454518..1455783(-) (cinA) [Streptococcus salivarius strain ATCC 27945]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGIITAQGVTYVVLPGPPSELKPM
VNQELIPALTENHSSLYSRVLRFFGVGESQLVTVLKDFIINQTDPTIAPYAKVGEVTLRLSTKASSQEEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEVFRLLKHHGKTITAAESLTAGLFQASIADFSGASQVFKGGFVTYSIEEKAKM
LDIPLSQLEEHGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDSLEGHLAGTVFIGIADRNQVRSIKVVIGGRSRSDI
RYISTLYAFNLVRQALLQETT

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=178228 NX99_RS06510 WP_084915128.1 1454518..1455783(-) (cinA) [Streptococcus salivarius strain ATCC 27945]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACCGGGCAGATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGATAATGAAAACCGCCTACTTTCAGTTCTTG
ATCAGGCTAGTCAACGTAGTGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACTTAACCAAGCAAACA
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGTCAAGCACAAATTGTTGAGGGAGCTATTCCCTTGCAAAACCCGACAGGTC
TTGCAGTTGGAGGGATTATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAAGAACTTATTCCAGCTCTTACTGAGAATCACTCAAGTCTTTATTCGAGAGTCCTAAGATTCTTCGGCGTTGG
AGAAAGTCAATTAGTGACTGTTCTGAAGGATTTTATTATTAACCAAACAGATCCAACCATAGCTCCATATGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCAACAAAGGCTTCTTCGCAAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAGAAACAA
ATTCGTTCGACTAAAACTCTAGATGGAAAATCCTTATCTGATTTCATTTATGGATATGGAGAGTCTAATAGTTTAGCCTT
TGAAGTTTTTCGCTTGCTTAAGCACCACGGCAAGACTATCACTGCAGCGGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
GTATTGCTGATTTTTCAGGGGCCTCACAAGTATTTAAAGGTGGCTTTGTTACTTATAGCATTGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTGTCGCAACTAGAAGAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCTCG
AGCTAAAACAGATAGCGATTATGGAATTGCACTTACCGGTGTAGCTGGACCAGATTCATTAGAAGGACACCTAGCAGGTA
CGGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGATATT
AGATATATTAGTACCCTATATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGACAACTTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.179

99.525

0.748
  cinA Streptococcus mitis NCTC 12261

74.463

99.525

0.741
  cinA Streptococcus pneumoniae TIGR4

73.747

99.525

0.734
  cinA Streptococcus pneumoniae Rx1

73.508

99.525

0.732
  cinA Streptococcus pneumoniae R6

73.508

99.525

0.732
  cinA Streptococcus pneumoniae D39

73.27

99.525

0.729
  cinA Streptococcus mutans UA159

71.703

99.05

0.71
  cinA Streptococcus suis isolate S10

55.769

98.812

0.551
  cinA Bacillus subtilis subsp. subtilis str. 168

45.368

100

0.454

Multiple sequence alignment