Detailed information NTG0177455

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: A4H00_RS09525
• Genome accession: NZ_CP015196
• Coordinates: 1937121..1937963 (+)
• Length: 280 a.a.
• NCBI ID: WP_067090206.1
• Uniprot ID: -
• Organism: Streptococcus marmotae strain HTS5
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1932121..1942963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4H00_RS09495	-	1932273..1932509 (+)	237	WP_067090188.1	helix-turn-helix domain-containing protein	-
A4H00_RS09500	-	1932858..1933091 (+)	234	WP_067090192.1	DNA-binding protein	-
A4H00_RS09505	-	1933166..1934673 (+)	1508	Protein_1827	tyrosine-type recombinase/integrase	-
A4H00_RS09510	ylqF	1934764..1935615 (+)	852	WP_067090196.1	ribosome biogenesis GTPase YlqF	-
A4H00_RS09515	-	1935602..1936393 (+)	792	WP_067090199.1	ribonuclease HII	-
A4H00_RS09520	-	1936380..1936934 (+)	555	WP_067090202.1	sugar O-acetyltransferase	-
A4H00_RS09525	dprA	1937121..1937963 (+)	843	WP_067090206.1	DNA-processing protein DprA	Machinery gene
A4H00_RS09530	topA	1938064..1940148 (+)	2085	WP_067090209.1	type I DNA topoisomerase	-
A4H00_RS09535	trmFO	1940449..1941795 (+)	1347	WP_067090212.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
A4H00_RS09540	-	1941885..1942325 (+)	441	WP_067090216.1	MerR family transcriptional regulator	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 30996.69 Da
• Isoelectric Point: 8.5508

>NTDB_id=177455 A4H00_RS09525 WP_067090206.1 1937121..1937963(+) (dprA) [Streptococcus marmotae strain HTS5]
MNNFELFKLKKAGLTNLNLHKVLAYQKDNGSSLSIKTIAQISECKNPVLFVEKYKQLDIKACREEFNRYPSLSILDDAYP
NELKQIYNPPVLLFYQGDIELLNKPKLAIVGARAASQTGTSSVQKIIKELGNHFVIVSGLARGIDTAAHISALKNGGKTI
AVIGSGLGVYYPKENKKLQDYIARHHLLLSEYEPDAQPLKYHFPERNRIIAGLSQGIIVAEAKKRSGSLITCERALEEGR
DVFAIPGSILDGKSDGCHYLIQEGEKCTTSGLDVLSEYQM

Nucleotide

• Length: 843 bp

>NTDB_id=177455 A4H00_RS09525 WP_067090206.1 1937121..1937963(+) (dprA) [Streptococcus marmotae strain HTS5]
ATGAATAACTTTGAATTGTTTAAATTAAAAAAAGCTGGATTGACGAATCTCAATCTTCATAAAGTATTGGCGTATCAAAA
GGATAATGGAAGTTCTTTATCGATTAAGACAATTGCGCAGATTTCAGAATGTAAAAATCCAGTTTTGTTTGTAGAGAAGT
ATAAGCAGTTGGATATAAAAGCTTGCCGTGAAGAGTTCAATCGTTATCCGTCGCTGTCCATTTTGGACGATGCCTATCCA
AATGAATTGAAACAGATTTATAATCCGCCAGTTCTGCTATTTTATCAAGGAGATATCGAACTATTAAACAAGCCTAAGTT
GGCTATTGTAGGAGCAAGAGCAGCTAGTCAGACAGGAACCAGTTCAGTCCAAAAAATTATTAAAGAATTAGGTAATCACT
TTGTTATTGTCAGTGGGTTGGCAAGAGGAATTGACACAGCAGCACATATTTCAGCCTTAAAAAACGGCGGTAAAACAATC
GCTGTTATCGGATCTGGTTTGGGGGTGTATTATCCAAAGGAAAATAAGAAGCTACAAGATTATATCGCTCGGCATCACTT
GCTACTTTCGGAGTATGAACCGGATGCCCAACCGCTTAAATATCATTTTCCAGAGCGAAATCGGATTATTGCGGGCTTAT
CACAAGGCATTATTGTCGCAGAGGCGAAAAAACGTTCTGGAAGTCTCATTACCTGCGAACGGGCCCTAGAAGAAGGACGA
GATGTTTTTGCTATTCCAGGATCCATTTTGGACGGAAAATCTGATGGATGTCATTATCTGATTCAAGAGGGAGAAAAGTG
TACTACATCAGGCTTAGACGTCCTATCAGAATACCAAATGTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.929	100	0.689
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	99.286	0.571
dprA	Legionella pneumophila strain ERS1305867	44.534	88.214	0.393
dprA	Vibrio campbellii strain DS40M4	39.56	97.5	0.386
dprA	Latilactobacillus sakei subsp. sakei 23K	43.83	83.929	0.368
dprA	Glaesserella parasuis strain SC1401	42.437	85	0.361
dprA	Bacillus subtilis subsp. subtilis str. 168	48.325	74.643	0.361