Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AYR52_RS06825 Genome accession   NZ_CP014623
Coordinates   1482459..1483706 (-) Length   415 a.a.
NCBI ID   WP_068225331.1    Uniprot ID   A0A192H542
Organism   Loigolactobacillus backii strain TMW 1.1988     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1477459..1488706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYR52_RS06810 (AYR52_06810) - 1477848..1478921 (-) 1074 WP_068225328.1 glycosyltransferase family 4 protein -
  AYR52_RS06815 (AYR52_06815) rny 1479323..1480885 (-) 1563 WP_068225329.1 ribonuclease Y -
  AYR52_RS06820 (AYR52_06820) recA 1481185..1482354 (-) 1170 WP_068225330.1 recombinase RecA Machinery gene
  AYR52_RS06825 (AYR52_06825) cinA 1482459..1483706 (-) 1248 WP_068225331.1 competence/damage-inducible protein A Machinery gene
  AYR52_RS06830 (AYR52_06830) pgsA 1484036..1484623 (-) 588 WP_068225332.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AYR52_RS06835 (AYR52_06835) - 1484792..1485796 (-) 1005 WP_068225333.1 helix-turn-helix domain-containing protein -
  AYR52_RS06840 (AYR52_06840) ymfI 1485882..1486610 (-) 729 WP_068225334.1 elongation factor P 5-aminopentanone reductase -
  AYR52_RS06845 (AYR52_06845) yfmH 1486614..1487912 (-) 1299 WP_068225335.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45335.89 Da        Isoelectric Point: 5.8058

>NTDB_id=172820 AYR52_RS06825 WP_068225331.1 1482459..1483706(-) (cinA) [Loigolactobacillus backii strain TMW 1.1988]
MRAEIIAVGTEILLGEITNTTTPFIARQLADLGIDVYYQSVVGDNADRLEQAIQLADTRSDLIILTGGLGPTKDDLTKQT
LAKHVNEKLVINDAAMGVINQYFIRSQRLMTENNRIQAMLPEHSQPLDNPVGMAVGALYQATKHTYMLLPGPPSELIAMF
EQSARPVLVKLYAQNNVLVSRVLRFHGIGESELVTRLADLIDHQTNPTIAPYAKINEVTLRITAEAKQEQLANQMLDQIE
ISIKAQVGNYFYGYGEHNSLPAVVVNLLKQRQLSITAAESLTAGMFQSEIGSIAGASTIFNGGFVTYSLAEKAHLLNIPT
ADLKKFGVVSEETAIAMARQAKAALQTDIGISFTGVAGPDELEGQPAGTVYIGIAYRDQAPEAHLFHFSRTRNLVRQQSV
LTGFDLLLHKLQADK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=172820 AYR52_RS06825 WP_068225331.1 1482459..1483706(-) (cinA) [Loigolactobacillus backii strain TMW 1.1988]
ATGCGTGCAGAAATTATTGCAGTTGGAACGGAAATACTTTTAGGTGAGATTACGAACACAACGACACCCTTTATTGCTCG
ACAATTGGCCGATTTAGGGATTGATGTTTACTATCAGAGCGTTGTTGGTGATAATGCAGATCGTTTGGAACAGGCAATTC
AACTTGCGGATACGCGAAGTGATTTAATTATTTTAACTGGTGGACTAGGACCAACTAAAGATGATTTAACAAAACAAACT
TTAGCGAAGCATGTAAACGAAAAACTAGTTATTAATGATGCGGCAATGGGTGTAATTAATCAGTATTTTATACGATCGCA
GCGCCTGATGACGGAAAATAATCGAATTCAGGCAATGCTACCTGAACATAGTCAGCCATTGGATAATCCCGTCGGTATGG
CCGTTGGTGCACTTTACCAAGCAACTAAGCATACTTATATGTTGTTGCCTGGACCGCCAAGTGAGCTAATTGCAATGTTT
GAACAATCTGCCCGGCCTGTACTAGTAAAACTTTACGCACAGAATAATGTTTTGGTTTCGCGCGTTTTACGATTTCACGG
GATTGGTGAGTCGGAATTAGTTACACGTTTGGCCGATTTAATTGATCACCAGACCAACCCAACCATTGCCCCCTACGCGA
AAATCAACGAAGTAACTTTGCGAATTACCGCCGAAGCAAAGCAGGAACAACTTGCCAATCAAATGCTAGATCAAATTGAA
ATTTCAATTAAGGCTCAGGTTGGTAATTATTTCTATGGTTACGGCGAGCATAATTCTTTGCCGGCCGTCGTAGTAAACTT
ATTAAAGCAGCGCCAGTTGTCGATAACTGCCGCCGAAAGTTTAACTGCCGGCATGTTCCAAAGTGAAATTGGCAGTATTG
CTGGTGCATCGACCATTTTTAATGGTGGCTTTGTAACCTATTCTTTGGCCGAAAAAGCACATTTACTCAATATTCCTACG
GCTGATTTAAAGAAATTCGGCGTTGTGAGCGAAGAAACGGCGATCGCAATGGCCCGGCAAGCTAAGGCCGCATTACAAAC
TGATATTGGTATTTCTTTTACTGGGGTGGCTGGACCTGACGAGCTAGAAGGACAACCAGCCGGAACCGTTTATATTGGCA
TTGCGTATCGTGATCAGGCTCCGGAAGCACACTTATTTCATTTTTCGAGAACACGTAACTTGGTTCGGCAACAAAGTGTT
TTAACTGGTTTTGATTTATTGCTGCATAAGTTGCAAGCTGATAAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(259-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A192H542

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.435

100

0.518
  cinA Streptococcus mitis NCTC 12261

50.355

100

0.513
  cinA Streptococcus mitis SK321

50.237

100

0.511
  cinA Streptococcus pneumoniae D39

49.531

100

0.508
  cinA Streptococcus pneumoniae TIGR4

49.882

100

0.508
  cinA Streptococcus pneumoniae Rx1

49.645

100

0.506
  cinA Streptococcus pneumoniae R6

49.645

100

0.506
  cinA Bacillus subtilis subsp. subtilis str. 168

47.689

99.036

0.472
  cinA Streptococcus suis isolate S10

40.821

99.759

0.407

Multiple sequence alignment